The Nupsala Podcast

In this episode of the Nupsala Podcast, host Meg Brady, BSc (Hons), RVN, PGCert, is joined by Andy Green, BVetMed MRCVS, veterinary surgeon and founder of Andy Green Consulting, for an in-depth conversation on building healthier, more effective workplace cultures within the veterinary profession. Together, they explore the critical role of communication in practice life, and how understanding individual personality profiles can transform team dynamics, reduce conflict, and improve collaboration. Drawing on real-world experience, Andy shares practical insights into why communication breakdowns occur- and what teams can do to address them.   This episode covers: How different personality profiles influence communication and teamwork Common causes of communication breakdown in veterinary practices and how to overcome them The key characteristics of a healthy, supportive workplace culture The impact and risks of blame culture within clinical teams An overview of personality profiling tools and how they can be applied in practice Strategies for maintaining autonomy, clarity, and structure in high-pressure environments Whether you’re part of a clinical team, a practice leader, or simply interested in improving workplace culture, this episode offers practical, actionable insights to help create more cohesive and resilient veterinary teams. Disclaimer: This podcast is intended for veterinary professionals. While members of the public are welcome to listen, please note that discussions are designed with a clinical audience in mind and may include technical or treatment-related content. Intro music by Lunar Year.

In this episode of the Nupsala Podcast, we’re joined by Dr Jason Lowe, equine veterinarian and Chief Veterinary Officer at Contura, to take a deep dive into his 2024 paper examining the histologic and cytologic response of normal equine joints following injection with 2.5% injectable polyacrylamide hydrogel (iPAAG). With over 30 years of global clinical experience, Dr Lowe walks us through the rationale, design and key findings of this in vivo safety study, explaining what a low-level macrophage-driven foreign body response actually means in practice, and why it should not be confused with fibrosis, granuloma formation, or adverse inflammatory reactions. The discussion explores: How iPAAG integrates into the synovium and restores joint biomechanics Why a transient macrophage response is part of normal tissue integration What scanning electron microscopy revealed about gel behaviour and stability Practical clinical takeaways around case selection, dosing, timelines for response, and managing post-injection flares How this work fits into a broader shift towards viewing the synovium as the key organ of the joint Dr Lowe also looks ahead to emerging research into macrophage phenotypes, transcriptomics, and how restoring joint biomechanics may influence downstream inflammatory pathways in osteoarthritis. This episode is essential listening for equine vets using (or considering) iPAAG as part of long-term osteoarthritis management, and for anyone interested in the evolving science behind synovial-focused therapies. References mentioned: Lowe, J., Clifford, L. de, Julian, A., & Koene, M. (2024). Histologic and cytologic changes in normal equine joints after injection with 2.5% injectable polyacrylamide hydrogel reveal low-level macrophage-driven foreign body response. Journal of the American Veterinary Medical Association, 262(5), 649–647. Tnibar, A. et al. (2015) International multi-centre prospective study on the efficacy of an intraarticular polyacrylamide hydrogel in horses with osteoarthritis: a 24 months follow-up. Acta veterinaria scandinavica. [Online] 57 (1). Menarim, B. C., MacLeod, J. N., & Dahlgren, L. A. (2021). Bone marrow mononuclear cells for joint therapy: The role of macrophages in inflammation resolution and tissue repair. World journal of stem cells, 13(7), 825–840.

In this episode of the Nupsala Podcast, we’re joined by Ross Allan BVMS PGCertSAS MRCVS, RCVS Advanced Practitioner in Small Animal Surgery and Clinical Director of Referrals at Pets’n’Vets, Glasgow. Ross shares his approach to managing canine osteoarthritis in first-opinion practice, with a focus on intra-articular diagnostics and therapies, collaborative team-based care, and realistic long-term management for osteoarthritic patients. He introduces the Joint Organ Concept, which views the joint as a living system of interacting tissues, helping clinicians better understand disease progression and treatment effects. The episode also covers Ross’s work with the Veterinary Osteoarthritis Alliance (VOA) and the RCVS Knowledge Cruciate Registry, a free quality-improvement initiative using real-world data to improve outcomes for dogs undergoing cruciate surgery. Links mentioned: RCVS Knowledge Cruciate Registry: https://ccr.rcvsknowledge.org/ Veterinary Osteoarthritis Alliance: https://vet-oa.com/ VOACON tickets: https://vet-oa.com/voacon-2026/

Meg Brady, Nupsala Account Manager, is joined by Dr Simon Constable, Advanced Practitioner in Equine Orthopaedic and Soft Tissue Surgery and owner of Simon Constable Equine Vets in the northwest of England. Simon shares his real-world experience using undifferentiated equine umbilical mesenchymal stem cells across both soft-tissue and early-onset joint cases.   He talks through how he selects cases, why timing and diagnostics matter, and how he manages owner expectations in disciplines where competition schedules and performance pressure can shape clinical decisions.   Simon also discusses client communication, insurance hurdles, alternatives to steroids in laminitis-prone ponies, and some of the more memorable cases he’s worked on, including a Horse of the Year Show winner.   Simon is not endorsed by or affiliated with Nupsala or Equicord.

In this Pain Awareness Month special, Meg Brady (RVN, BSc, PGCert, EQ.Sci) speaks with Dr. Matt Gurney, internationally respected anaesthetist, co-founder of the Zero Pain Philosophy, and past president of the European College of Veterinary Anaesthesia and Analgesia.   Matt shares his journey into anaesthesia and analgesia, the inspiration behind the Zero Pain Philosophy, and how his team supports vets, nurses, and physios worldwide in improving pain management. He discusses practical tools for acute and chronic pain, including the Glasgow Pain Scale, Feline Grimace Scale, LOAD, and the Canine Brief Pain Inventory, and explains how caregiver-reported outcomes can shape effective treatment plans.   This episode also highlights the role of community, clinical audits, and checklists in improving standards of care, and why vets should embrace a multimodal, evidence-informed approach to pain management in practice. References discussed: www.zeropainphilosophy.com Animal Pain – www.animalpain.org/en/home-en/ University of Glasgow - www.gla.ac.uk/research/impact/painassessmenttools/ Modified Canine Brief Pain Inventory - www.edwebcontent.ed.ac.uk/sites/default/files/atoms/files/modified_canine_brief_pain_inventory_1.3.17_edinburgh.pdf www.knowledge.rcvs.org.uk/home/ Brown DC, Boston RC, Coyne JC, et al. (2013). Ability of the canine brief pain inventory to detect response to treatment in dogs with osteoarthritis. J Am Vet Med Assoc. 233. P1278–83.

In this Pain Awareness Month special, Amber Weinrich (RVN, Nupsala Account Manager) speaks with Meg Brady (RVN, Nupsala Senior Account Manager) about recognising pain in dogs and how subtle behaviour changes can be key indicators. They explore how pain influences behaviour, how vets and owners can work together to detect it, and which clinical tools are available to support diagnosis and monitoring. Meg discusses the link between pain and problem behaviours, the "ladder of aggression," and concepts such as trigger stacking, central sensitisation, and owner perception of pain in younger vs. older dogs. This episode highlights the importance of asking the right questions, using structured assessment tools, and revisiting pain as a possible underlying cause when behavioural modifications are unsuccessful.   References discussed: Mills, D. S. et al. (2020). Pain and Problem Behavior in Cats and Dogs. Animals (Basel). 10. 2. P318. Shepherd, K. Ladder of aggression. In BSAVA Manual of Canine and Feline Behavioral Medicine; Horwitz, D.F., Mills, D.S., Eds.; BSAVA: Gloucester, UK, 2009; Chapter 2 p13–16. DogMA (Liverpool University) https://www.liverpool.ac.uk/life-course-and-medical-sciences/research/dogma/ Brown DC, Boston RC, Coyne JC, et al. (2013). Ability of the canine brief pain inventory to detect response to treatment in dogs with osteoarthritis. J Am Vet Med Assoc. 233. P1278–83. Demirtas, A. et al. (2023). Dog owners' recognition of pain-related behavioral changes in their dogs. Journal of Veterinary Behavior. 62. P39-46 Mills, DS, Coutts, FM & McPeake, KJ. (2024). Behavior Problems Associated with Pain and Paresthesia. Veterinary Clinics of North America: Small Animal Practice. 54. 1. P55-69 Mondino, A. et al. (2023). Development and validation of a sleep questionnaire, SNoRE 3.0, to evaluate sleep in companion dogs. Scientific reports. [Online] 13 (1), 13340–13340. Walton MB, Cowderoy E, Lascelles D, et al. (2013). Evaluation of construct and criterion validity for the ’Liverpool Osteoarthritis in Dogs’ (LOAD) clinical metrology instrument and comparison to two other instruments. PLoS One. 8. e58125.

The Nupsala Podcast | Episode 1 HorStem Welcome to the very first episode of The Nupsala Podcast! In this episode, we sit down with Almudena Pradera, founder of Equicord, to explore the science behind Horstem, a cutting-edge veterinary stem cell therapy derived from umbilical cord tissue. Disclaimer: This podcast is intended for veterinary professionals. While members of the public are welcome to listen, please note that the discussions are designed with a clinical audience in mind and may include technical or treatment-related content. If you’re a horse owner with questions or concerns, we always recommend speaking directly with your own veterinary surgeon, who knows your animal best. For more information, contact a member of our sales team or reach out to customer services at: [email protected] Or visit www.equicord.com to learn more about Equicord and their work.

In this episode, Greg McGarrell sits down with Dr. Mark Bowen, an equine internal medicine specialist, to explore a groundbreaking approach to managing equine asthma. Moving beyond traditional treatments like clenbuterol and corticosteroids, Mark shares how a biologic derived from the horse’s own blood is offering a promising alternative — especially for competition horses where drug regulations are tight. They discuss the origins of equine asthma as a diagnosis, the limitations of conventional therapies, and how biologics might serve as a safer, drug-free anti-inflammatory option. With real-world examples, delivery protocols, and an honest look at what science can and can’t yet explain, this episode dives deep into the future of respiratory care in horses. Whether you treat performance horses, manage yard favourites, or simply want a glimpse of where respiratory medicine is heading, this conversation delivers practical insight—and plenty to think about. Have a question or referral? Contact Dr Bowen at [email protected] or +44 (0)115 647 0660. Editors Note: A small correction to this podcast is that Ciclesonide has a 120 hour urine detection time not 72 hours as discussed.

With Julie Burns (Endometriosis UK Friendly Employer Scheme Manager), Harriet Tims (Operations Manager at Nupsala), and Kelly Masters (Clinical Support at MSK Vets). In this special episode of The Nupsala Podcast, we take a step away from our usual animal healthcare focus to highlight a human health issue that deserves far greater attention: Endometriosis. Earlier this year, Nupsala became an Endometriosis Friendly Employer, and this conversation is part of our ongoing commitment to creating a more inclusive, supportive, and understanding workplace for women’s health needs. Even if you’ve never experienced Endometriosis yourself, your awareness and understanding can make a real difference in fostering a culture of openness, compassion, and support. With 1 in 10 women living with Endometriosis, many continue to endure it without adequate recognition, treatment, or workplace support. For more information on Endometriosis or on becoming a Endometriosis Friendly Employer please visit: https://www.endometriosis-uk.org   Together with our guests, we discuss: ✔ Busting common myths and misconceptions about endometriosis 
✔ Effective management and treatment approaches
 ✔ How workplaces can better support employees with endometriosis
 ✔ What it means to be an Endometriosis Friendly Employer
 ✔ Practical steps to improve policies, culture, and awareness around women’s health   Check out the Women and Equalities Committee’s report on Women’s Reproductive Health Conditions: https://committees.parliament.uk/publications/45909/documents/228040/default/   To stay updated on new episodes, CPD opportunities, and upcoming events, follow us on our social channels: LinkedIn: https://www.linkedin.com/company/nupsala-uk FaceBook: https://www.facebook.com/nupsala-veterinary-services Instagram: https://www.instagram.com/nupsalaveterinaryservices   For more information, professional resources or any of your wholesale needs, visit www.nupsala.com.   Disclaimer: This podcast is intended primarily for professionals and workplace leaders. While everyone is welcome to listen, please note that the discussions may include health-related and organisational content designed with a professional audience in mind. Music Credit: Intro Music by Lunar Year

The Nupsala Podcast Bitesized: Mesenchymal Stem Cells in the Chronic OA Patient (Autologous or Xenogenic) with Greg McGarrell (CEO of Nupsala) & Russell Chandler (Veterinary Orthopaedic Surgeon, dual MSc) In this bite-sized episode, Russell and Greg explore the role of Mesenchymal Stem Cells in the chronic osteoarthritic patient, including their rationale for selecting autologous versus xenogeneic sources. This episode was recorded live at VOACON 2025 and is an excerpt from The Nupsala Podcast Episode 4 - The Current Landscape of Intra-Articular Therapy in Small Animals (Watch Full Episode). – Watch or listen to the all episodes of The Nupsala Podcast on YouTube, Spotify, Apple Podcasts, and Amazon Podcasts. Simply search The Nupsala Podcast in your preferred streaming platform. For further information and professional advice, please visit www.nupsala.com To stay updated on new episodes, CPD opportunities, and upcoming events, follow us on our social channels: LinkedIn Facebook Instagram Disclaimer: This podcast is intended for veterinary professionals. While members of the public are welcome to listen, please note that the discussions are designed with a clinical audience in mind and may include technical or treatment-related content. Intro Music by Lunar Year.

The Nupsala Podcast Bite Sized: Polyacrylamide Hydrogels with Greg McGarrell (CEO of Nupsala) & Russell Chandler (Veterinary Orthopaedic Surgeon, dual MSc) This episode was recorded live at VOACON 2025 and is an excerpt from The Nupsala Podcast Episode 4 – The Current Landscape of Intra-Articular Therapy in Small Animals. In this bite-sized episode, Russel and Greg discuss the use of Polyacrylamide Hydrogels and the importance of regenerating the synovial membrane. – Watch or listen to the full episode on YouTube, Spotify, Apple Podcasts, and Amazon Podcasts. For further information and professional advice, please visit www.nupsala.com To stay updated on new episodes, CPD opportunities, and upcoming events, follow us on our social channels: LinkedIn Facebook  Instagram Disclaimer: This podcast is intended for veterinary professionals. While members of the public are welcome to listen, please note that the discussions are designed with a clinical audience in mind and may include technical or treatment-related content. Intro Music by Lunar Year.

The Nupsala Podcast Episode 4: The Current Landscape of Intra-Articular Therapy in Small Animals with Greg McGarrell (CEO of Nupsala) & Russell Chandler (Veterinary Orthopaedic Surgeon, dual MSc) This episode was recorded live at VOACON 2025. Russell Chandler and Greg McGarrell discuss intra-articular medications and orthobiologics in the management of canine osteoarthritis, drawing comparisons with current applications in equine veterinary medicine. This is the full version of Episode 4 of the Nupsala Podcast. If you prefer shorter content, you can find bite-sized clips focusing on polacrylamide hydrogels and stem cells on our podcast channels. For further information and professional advice, please visit www.nupsala.com To stay updated on new episodes, CPD opportunities, and upcoming events, follow us on our social channels: LinkedIn Facebook  Instagram Disclaimer: This podcast is intended for veterinary professionals. While members of the public are welcome to listen, please note that the discussions are designed with a clinical audience in mind and may include technical or treatment-related content. Intro Music by Lunar Year.

In this episode of the Nupsala Podcast, we’re joined by Dr. Alexandra Keller, Veterinary Specialist in Chiropractic at the Veterinary Orthopaedic Team Frankfurt, and Meg Brady, Senior Account Manager at Nupsala. Together, they explore how regenerative medicine is being used in clinical practice to support canine musculoskeletal health. From stem cell therapy to platelet-rich plasma (PRP), this conversation delves into the practical applications, challenges, and real-world outcomes of regenerative techniques. Whether you're a vet, therapist, or simply passionate about canine rehabilitation, this episode offers valuable insight into an evolving and exciting area of veterinary care. For more information and advice, visit www.nupsala.com

In this episode, Dr. Lauren Davis (VetRelieve CEO and canine sleep expert) joins Meg Brady to explore the often overlooked connection between sleep and pain in animals. They unpack the science behind canine sleep, its role in recovery, and practical strategies for veterinary professionals and pet owners. VetRest Duo and advice are available at www.Nupsala.com   For more information, contact a member of our sales team or reach out to customer services at: www.vetrelieve.co.uk to learn more about VetRelieve and their work.  Intro music by Lunar Years.