PODCAST · science
Futures in Biotech (Audio)
by TWiT
Explore the world of cloning, protein folding, genome mapping, and more with the most important researchers in the field.Although the show is no longer in production at TWiT, you can enjoy episodes from the TWiT Archives.
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94
FiB 95: So Long and Thanks for All the FiBs
We bring back all the co-hosts, panelists, and subject matter experts for a touchy feeling - warm and fuzzy feel good farewell. FiB is moving to: Microbe TV Host: Marc Pelletier Guests: George Farr, Ph.D., Mark Griswold, Jasen Buch, Vincent Racaniello, Ph.D, Andre Nantel, Ph.D, David Thomas, Justin Sanchez, Ph.D, and Dave Brodbeck, Ph.D Thanks to Phil Pelletier and Will Hall for the great themes. Thanks to CacheFly for providing the bandwidth for this netcast.
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93
FiB 94: Getting DNA Right-s
We navigate the waters of Biotechnology. Gene patents, how do you get them and why are they there? And once you have them, how are you going to finance your company and move forward? Eileen Smith Ewing is a shareholder of GreenbergTraurig, Boston, MA; Chair, Committee on Biotechnology; & Chair, Life Sciences Division, American Bar Association Hosts: Marc Pelletier and Denise Howell Guest: Eileen Smith Ewing Thanks to Phil Pelletier and Will Hall for the great themes. Thanks to CacheFly for providing the bandwidth for this netcast.
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92
FiB 93: Snyder's Omics
The technologies that our guest has developed are playing an important role in changing the world, not like the car, the microwave and the cell phone, but as in Drs. Flox, McCoy, and Crusher. Host: Marc Pelletier Co-Host: Andre Nantel, Ph.D Guest: Dr. Michael Snyder Thanks to Phil Pelletier and Will Hall for the great themes. Thanks to CacheFly for providing the bandwidth for this netcast.
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91
FiB 92: Foldit - Crowd Sourcing God's Work
Dr. David Baker explains how the game Foldit uses crowdsourcing to intelligently design artificial proteins never seen before in nature. Host: Marc Pelletier Co-Host: Markus Veolter Guest: Dr. David Baker Thanks to Phil Pelletier and Will Hall for the great themes. Thanks to CacheFly for providing the bandwidth for this netcast.
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90
FiB 91: 6 PhDs Piled High and Deep
In this episode of Futures in Biotech, we talk about the Frontiers of Biotechnology - where the line between science and sci-fi are beginning to blur. Host: Marc Pelletier Guests: George Farr, Ph.D., Mark Gerstein, David Thomas, Justin Sanchez, Ph.D, and Simon Melov, PhD Thanks to Phil Pelletier and Will Hall for the great themes. Thanks to CacheFly for providing the bandwidth for this netcast.
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89
FiB 90: In-Silico Models of Organ Morphogenesis
In this episode of Futures in Biotech, Dr. Celeste Nelson, from Princeton University, explores the fundamental mechanisms of organ morphogenesis. Host: Marc Pelletier Co-Host: Andre Nantel, Ph.D Guest: Dr. Celeste Nelson, Ph.D. Thanks to Phil Pelletier and Will Hall for the great themes. Thanks to CacheFly for providing the bandwidth for this netcast. Sponsor: Ford Technology
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88
FiB 89: Towards Curing Malaria With Dr. Elizabeth Winzeler
Dr. Elizabeth Winzeler describes her approaches to drug discovery in an effort to tackle Malaria. Host: Marc Pelletier Guest: Dr. Elizabeth Winzeler, Ph.D. Thanks to Phil Pelletier and Will Hall for the great themes. Thanks to CacheFly for providing the bandwidth for this netcast. Sponsor: Ford
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87
FiB 88: Cogito, Ergo Sum... Multitasking?
How understanding our mind will shape our futures with Dr. Adam Gazzaley. Host: Marc Pelletier Co-Host: Dave Brodbeck, Ph.D Guest: Adam Gazzaley Thanks to Phil Pelletier and Will Hall for the great themes. Thanks to CacheFly for providing the bandwidth for this netcast. Sponsor: Ford
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86
FiB 87: Anti-Matter Message in a Magnetic Bottle
We talk with Jeffrey Hangst about the successful trapping of anti-hydrogen to hopefully answer some of our most important questions about the universe. Host: Marc Pelletier Guest: Jeffrey Hangst Thanks to Phil Pelletier and Will Hall for the great themes. Thanks to CacheFly for providing the bandwidth for this netcast.
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85
FiB 86: Biomasses for the Masses
Changing an Amish farm in Ohio into an energy source solution for modern times. Host: Marc Pelletier Guests: Jon Griswold, Matthew J. Griswold, CFA, and Mark Griswold Thanks to Phil Pelletier and Will Hall for the great themes. Thanks to CacheFly for providing the bandwidth for this netcast.
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84
FiB 85: Modeling Life With the World's Most Powerful Computer System
Dr. Vijay Pande, Stanford's Director of Folding@Home, details how the world's most powerful system models Alzheimer's and other human diseases. Host: Marc Pelletier Guest: Vijay S. Pande Thanks to Phil Pelletier and Will Hall for the great themes. Thanks to CacheFly for providing the bandwidth for this netcast.
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83
FiB 84: Biotech - Hot in Cleveland
Baiju Shah, President & CEO of BioEnterprise, explains how to transform a regional economy into a thriving biotechnological innovation center. Host: Marc Pelletier Guest: Baiju Shah, J.D. Thanks to Phil Pelletier and Will Hall for the great themes. Thanks to CacheFly for providing the bandwidth for this netcast.
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82
FiB 83: Bioinformatics: Essential Gene Names Skewed in a Network of Blame
Dr. Mark Gerstein from Yale University explains the essence of life through network theory. Here you can find an important podcast: Biological Network Analysis Host: Marc Pelletier Guest: Mark Gerstein Thanks to Phil Pelletier and Will Hall for the great themes. Thanks to CacheFly for providing the bandwidth for this netcast.
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81
FiB 82: Bionic Brain Symbionts: The Next Phage of Human Slurry
We discuss everything from symbiotic devices to human proteome phage to the race between transcription and translation, genetics gone wild. Host: Marc Pelletier Guests: Andre Nantel, Ph.D and Justin Sanchez, Ph.D Thanks to Phil Pelletier and Will Hall for the great themes. Thanks to CacheFly for providing the bandwidth for this netcast.
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80
FiB 81: Worm Research: The Buck Starts Here
Dr. Gordon Lithgow bridges the science of protein folding and life extension. Host: Marc Pelletier Co-Host: Simon Melov, PhD Guest: Gordon Lithgow, Ph.D. Thanks to Phil Pelletier and Will Hall for the great themes. Thanks to CacheFly for providing the bandwidth for this netcast.
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79
FiB 80: Light Up the Brain
Using optogenetics to study learning and cognition. Host: Marc Pelletier Co-Host: Dave Brodbeck, Ph.D Guest: Dr. Ann M. Graybiel Thanks to Phil Pelletier and Will Hall for the great themes. Thanks to CacheFly for providing the bandwidth for this netcast.
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78
FiB 79: Oceans 20
The Test Run, the technology that will transition us into the next era of medicine. Host: Marc Pelletier Co-Host: Mark Gerstein Guest: Dr. Tommy Nilsson Thanks to Phil Pelletier and Will Hall for the great themes. Thanks to CacheFly for providing the bandwidth for this netcast.
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77
FiB 78: TWiV Infects FiB
It's a science mashup. FiB and TWiV together for one big show. Hosts: Marc Pelletier and Vincent Racaniello, Ph.D Guests: Dickson D. Despommier, Ph.D., Alan Dove, Ph.D, and Richard Condit, Ph.D Thanks to Phil Pelletier and Will Hall for the great themes. Thanks to CacheFly for providing the bandwidth for this netcast.
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76
FiB 77: How The Environment and A Single Protein Influence Evolution
How the environment and a single protein influence evolution. Host: Marc Pelletier Guests: Dr. Susan Lindquist and Daniel Jarosz, Ph.D. Thanks to Phil Pelletier and Will Hall for the great themes. Thanks to CacheFly for providing the bandwidth for this netcast.
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75
FiB 76: It's Time To Proteo Me
How mass spectrometry has become one of the most important technologies in our move toward personalized medicine. Hosts: Marc Pelletier and Vincent Racaniello, Ph.D Guest: Ruedi Aebersold Sponsored by: Synergy 1. Thanks to Phil Pelletier and Will Hall for the great themes. Thanks to CacheFly for providing the bandwidth for this netcast.
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74
FiB 75: It's Time To Start the Human Proteome
The move to the Human Proteome is the next big transition in modern medicine. Host: Marc Pelletier Guests: Dr. John Bergeron and Dr. Tommy Nilsson Sponsored by: Synergy 1. Thanks to Phil Pelletier and Will Hall for the great themes. Thanks to CacheFly for providing the bandwidth for this netcast.
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73
FiB 74: Cancer and Aging: Rival Demons with Dr. Judith Campisi
Dr. Judith Campisi's scientific investigations are at the nexus between cancer and aging. She seeks to better understand how cellular senescence contributes to the pathophysiology of aging. Host: Marc Pelletier Guests: Simon Melov, PhD and Dr. Judith Campisi, Ph.D. Sponsored by: Synergy 1. Thanks to Phil Pelletier and Will Hall for the great themes. Thanks to CacheFly for providing the bandwidth for this netcast.
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72
FiB 73: The New Science of Aging
We will discuss the biotech of life extension with the scientist that discovered the Sirtuan family of genes. Host: Marc Pelletier Guest: Simon Melov, PhD Thanks to Phil Pelletier and Will Hall for the great themes. Thanks to CacheFly for providing the bandwidth for this netcast.
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71
FiB 72: A Four Billion Year Old Social Network
How controlling bacterial behavior may lead to a new class of urgently needed antibiotics. Host: Marc Pelletier Guest: Dr. Bonnie Bassler Sponsored by: Synergy 1. Thanks to Phil Pelletier and Will Hall for the great themes. Thanks to CacheFly for providing the bandwidth for this netcast.
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70
FiB 71: Genomics, Proteomics, Cellular Immunity, and Anti-Matter
The '1000 Genome Project', 'Billion Dollar Human Proteome', viral killing proteins, and capturing anti-matter. Hosts: Marc Pelletier, Vincent Racaniello, Ph.D, and Andre Nantel, Ph.D Co-Host: George Farr, Ph.D. Guest: Mark Gerstein Sponsored by: Synergy 1. Thanks to Phil Pelletier and Will Hall for the great themes. Thanks to CacheFly for providing the bandwidth for this netcast.
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69
FiB 70: SBIR Funding: The Business of Science
How to fund the development of your own technology through SBIR funding. Host: Marc Pelletier Guest: Lisa Kurek For a free audiobook, visit Audible.com/biotech. Thanks to Phil Pelletier and Will Hall for the great themes. Thanks to CacheFly for providing the bandwidth for this netcast.
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68
FiB 69: The Power of Yeast Genetics
Looking at one of the most powerful genetic model systems, Saccharomyces cerevisiae, with Malcolm Whiteway, Ph.D NRC-CNRC Group leader for Biotechnology Research institute, National Research Council of Canada, Montreal. Hosts: Marc Pelletier and Vincent Racaniello, Ph.D Guest: Malcolm Whiteway, Ph.D For a free audiobook, visit Audible.com/biotech. Thanks to Phil Pelletier and Will Hall for the great themes. Thanks to CacheFly for providing the bandwidth for this netcast.
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67
FiB 68: Rats Will Inherit the Earth
How studying mammalian biological history can help us better understand ourselves. Host: Marc Pelletier Guest: Darin Croft, Ph.D For a free audiobook, visit Audible.com/biotech. Thanks to Phil Pelletier and Will Hall for the great themes. Thanks to CacheFly for providing the bandwidth for this netcast.
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66
FiB 67: Triceratopping Egg Mountain
Dinosaur hunting with the man who inspired Jurassic Park, Dr. Jack Horner, curator of Paleontology at the Museum of the Rockies and Montana State University Regents' Professor of Paleontology. Host: Marc Pelletier Guest: Dr. Jack Horner For a free audiobook, visit Audible.com/biotech. Thanks to Phil Pelletier and Will Hall for the great themes. Thanks to CacheFly for providing the bandwidth for this netcast.
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65
FiB 66: The Homebrew Genomics Club
A first hand account on the genesis of the Human Genome Project with our guest, Dr. David Botstein, Director of the Lewis-Sigler Institute for Integrative Genomics at Princeton University. Hosts: Marc Pelletier and Andre Nantel, Ph.D Guest: Dr. David Botstein For a free audiobook, visit Audible.com/biotech. Thanks to Phil Pelletier and Will Hall for the great themes. Thanks to CacheFly for providing the bandwidth for this netcast.
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64
FiB 65: Tackling Genetic Disease
Progress in molecular biology and the latest strategies for tackling genetic disease. Our guest is David Thomas, professor and chair, Department of Biochemistry, McGill University; Canada Research Chair in Molecular Genetics. Hosts: Marc Pelletier and Dave Brodbeck, Ph.D Guest: David Thomas For a free audiobook, visit Audible.com/biotech. Thanks to Phil Pelletier and Will Hall for the great themes. Thanks to CacheFly for providing the bandwidth for this netcast.
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63
FiB 64: The Future Is Viral
Five scientists, George Farr, Mark Griswold, Dave Brodbeck, Vincent Racaniello and David Thomas, discuss their hopes and aspirations for biotechnology in a post-genomics era. Host: Marc Pelletier Guests: George Farr, Ph.D., Mark Griswold, Dave Brodbeck, Ph.D, Vincent Racaniello, Ph.D, and David Thomas For a free audiobook, visit Audible.com/biotech. Thanks to Phil Pelletier and Will Hall for the great themes. Thanks to CacheFly for providing the bandwidth for this netcast.
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62
FiB 63: How to Use a Mouse
Nobel Laureate Dr. Mario Capecchi teaches us how to use a mouse to dissect the human genome and understand disease. Our guest is Mario Capecchi, Ph.D., distinguished Professor of Human Genetics and Biology at the University of Utah and investigator with the Howard Hughes Medical Institute Host: Marc Pelletier Guest: Mario Capecchi, Ph.D. For a free audiobook, visit Audible.com/biotech. Thanks to Phil Pelletier and Will Hall for the great themes. Thanks to CacheFly for providing the bandwidth for this netcast.
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61
FiB 62: X-Ray Crystallography
Dr. Alexander McPherson explains X-ray crystallography, a technique that will produce a true atomic anatomy of the human body. Books referenced in this episode: Crystallization of Biological Macromolecules, COLD SPRING HARBOR LABS. Introduction to Macromolecular Crystallography, WILEY BLACKWELL. Host: Marc Pelletier Co-Host: George Farr, Ph.D. Guest: Dr. Alexander McPherson Thanks to Phil Pelletier and Will Hall for the great themes. Thanks to CacheFly for providing the bandwidth for this netcast.
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60
FiB 61: One Heart Beat Away
Tackling problems of the heart with biotechnology. Our guest is Julian Stelzer, Assistant Professor of Physiology and Biophysics, Case Western Reserve University Host: Marc Pelletier Guest: Julian E. Stelzer, PhD For a free audiobook, visit Audible.com/biotech. Thanks to Phil Pelletier and Will Hall for the great themes. Thanks to CacheFly for providing the bandwidth for this netcast.
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59
FiB 60: Do You Come to This Cave Often?
Primate face recognition, new cure for HVC, genetic base change, neanderthals and humans, and more. Host: Marc Pelletier Guests: Dave Brodbeck, Ph.D, Andre Nantel, Ph.D, Vincent Racaniello, Ph.D, and George Farr, Ph.D. For a free audiobook, visit Audible.com/biotech. Thanks to Phil Pelletier and Will Hall for the great themes. Thanks to CacheFly for providing the bandwidth for this netcast.
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58
FiB 59: No Room for Failure
A first hand account of the Apollo Missions from the floor of Mission Control from Michael Vucelic, former Apollo system manager for NASA and Rockwell. Host: Marc Pelletier Guest: Michael Vucelic For a free audiobook, visit Audible.com/biotech. Thanks to Phil Pelletier and Will Hall for the great themes. Thanks to CacheFly for providing the bandwidth for this netcast.
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57
FiB 58: Vertical Farms and Much, Much More With Dick Despommier
Feeding the world with indoor vertical farming. Our guest is Dickson D. Despommier, Ph.D., Professor of Microbiology, College of Physicians and Surgeons, Columbia University, New York, NY. Host of This Week in Virology; Host of This Week in Parasitism. Hosts: Marc Pelletier and Vincent Racaniello, Ph.D Guest: Dickson D. Despommier, Ph.D. For a free audiobook, visit Audible.com/biotech. Thanks to Phil Pelletier and Will Hall for the great themes. Thanks to CacheFly for providing the bandwidth for this netcast.
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56
FiB 57: Mechanisms of Non-Mendelian Inheritance in Evolution
How prion proteins can act in non-mendelian inheritance, or evolution without DNA. Our guests are Susan Lindquist, Ph.D., professor of biology at MIT and investigator of the Howard Hughes Medical Institute, Simon Alberti, group leader at the Max Planck Institute of Molecular Cell Biology and Genetics, and Randal Halfmann, a grad student in Dr. Lindquist's lab at MIT Host: Marc Pelletier Co-Host: George Farr, Ph.D. Guests: Dr. Susan Lindquist and Simon Alberti For a free audiobook, visit Audible.com/biotech. Thanks to Phil Pelletier and Will Hall for the great themes. Thanks to CacheFly for providing the bandwidth for this netcast.
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55
FiB 56: New Antiviral Strategies with Karla Kirkegaard
A look into RNA viruses and more with Dr. Karla Kirkegaard, professor and chair of the Department of Microbiology and Immunology at the Stanford University School of Medicine. Hosts: Marc Pelletier and Vincent Racaniello, Ph.D Guest: Dr. Karla Kirkegaard For a free audiobook, visit Audible.com/biotech. Thanks to Phil Pelletier and Will Hall for the great themes. Thanks to CacheFly for providing the bandwidth for this netcast.
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54
FiB 55: Ultra Low Power Bioelectronics, Part 2
Dr. Rahul Sarpeshkar, Ph.D., associate professor, of electrical engineering and computer science at the Massachusetts Institute of Technology, talks about how to improve electronic systems using biologically inspired design. Host: Marc Pelletier Guests: Justin Sanchez, Ph.D and Rahul Sarpeshkar, Ph.D. Thanks to Phil Pelletier and Will Hall for the great themes. Thanks to CacheFly for providing the bandwidth for this netcast.
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53
FiB 54: Personal Genome Project - Leo's Genome?
The Personal Genome Project: making personal genome sequencing more affordable, accessible, and useful. Our guest is Dr. George Church, Professor of Genetics at Harvard Medical School and Director of the Center for Computational Genetics. Hosts: Marc Pelletier and Leo Laporte Guest: Dr. George Church For a free audiobook, visit Audible.com/biotech. Thanks to Phil Pelletier and Will Hall for the great themes. Thanks to CacheFly for providing the bandwidth for this netcast.
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52
FiB 53: Project Genome 10K - Mapping Life's Greatest Journey
Project Genome 10k, and how sequencing ten thousand vertebrate genomes will tell us about our past, present, and future. Our guest is Dr. David Haussler, professor of biomolecular engineering, University of California at Santa Cruz, director of the Center for Biomolecular Science & Engineering, and investigator at the Howard Hughes Medical Institute Host: Marc Pelletier Guest: Dr. David Haussler For a free audiobook, visit Audible.com/biotech. Thanks to Phil Pelletier and Will Hall for the great themes. Thanks to CacheFly for providing the bandwidth for this netcast.
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51
FiB 52: Ultra Low Power Bioelectronics, Part 1
Bio-inspired and biomedical electronics, circuit modeling of biology, and more. Our guest is Rahul Sarpeshkar, Ph.D., associate professor of electrical engineering and computer science at the Massachusetts Institute of Technology and author of Ultra Low Power Bioelectronics: Fundamentals, Biomedical Applications, and Bio-inspired Systems Host: Marc Pelletier Guests: Justin Sanchez, Ph.D, Mark Griswold, and Rahul Sarpeshkar, Ph.D. For a free audiobook, visit Audible.com/biotech. Thanks to Phil Pelletier and Will Hall for the great themes. Thanks to CacheFly for providing the bandwidth for this netcast.
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50
FiB 51: MRI Engineering Made Easy
How to build an MRI, and how it works. Host: Marc Pelletier Guest: Mark Griswold For a free audiobook, visit Audible.com/biotech. Thanks to Phil Pelletier and Will Hall for the great themes. Thanks to CacheFly for providing the bandwidth for this netcast.
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49
FiB 50: More Biotech Stories
Marc and some the FiB regulars cover important stories in the biotechnology realm. Host: Marc Pelletier Guests: George Farr, Ph.D., Dave Brodbeck, Ph.D, Justin Sanchez, Ph.D, and Vincent Racaniello, Ph.D For a free audiobook, visit Audible.com/biotech. Thanks to Phil Pelletier and Will Hall for the great themes. Thanks to CacheFly for providing the bandwidth for this netcast.
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48
FiB 49: Brain-Machine Interfaces
Dr. Justin Sanchez, Assistant Professor of Pediatrics, Neuroscience, and Biomedical Engineering, and Biomedical Engineering at the University of Florida, walks us through the technology of brain machine interfaces. Hosts: Marc Pelletier and Dr. Kiki Sanford Guest: Justin Sanchez, Ph.D For a free audiobook, visit Audible.com/biotech. Thanks to Phil Pelletier and Will Hall for the great themes. Thanks to CacheFly for providing the bandwidth for this netcast.
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47
FiB 48: Sequencing an Ocean's Genome
Dr. Delong discusses the use of metagenomics to understand microbial life in the Pacific Ocean. Hosts: Marc Pelletier and Andre Nantel, Ph.D Guest: Edward Delong, Ph.D. For a free audiobook, visit Audible.com/biotech. Thanks to Phil Pelletier and Will Hall for the great themes. Thanks to CacheFly for providing the bandwidth for this netcast.
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46
FiB 47: Genetic Engineering in the 21st Century
Dr. Oliver Smithies discusses the present and future of genetic engineering Host: Marc Pelletier Guests: Andre Nantel, Ph.D and Dr. Oliver Smithies For a free audiobook, visit Audible.com/biotech. Thanks to Phil Pelletier and Will Hall for the great themes. Thanks to CacheFly for providing the bandwidth for this netcast.
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45
FiB 46: Towards Computers That Think
An interview with Dr. Terrence Sejnowski about theoretical and computational biology and neurobiology. Audible pick: This Is Your Brain on Music: The Science of a Human Obsession, Abridged, By Daniel J. Levitin, Narrated by Edward Herrman. For a free audiobook, visit Audible.com/biotech. Hosts: Marc Pelletier and Dave Brodbeck, Ph.D Guest: Terrence Sejnowski Thanks to Phil Pelletier and Will Hall for the great themes. Thanks to CacheFly for providing the bandwidth for this netcast.
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