RNA Metabolism: Changing Paradigms in Neurodegeneration

Peter Heutnik, Deutsches Zentrum für Neurodegenerative Erkrankungen e.V. (DZNE), Standort Tübingen, Tübingen - GERMANY - speaks on "CAGEseq expression profiling for genetically distinct forms of frontotemporal dementia(FTD) reveals common and distinct molecular pathways - RNA Metabolism: Changing Paradigms in Neurodegeneration” This seminar has been recorded at Area Science Park Trieste by ICGEB Trieste

Michael Strong, Dean, Schulich School of Medicine & Dentistry, Distinguished University Professor, Western University, Rix Clinical Skills Learning Building, London - CANADA speaks on miRNA modulation of NEFL mRNA stability in ALS - RNA Metabolism: Changing Paradigms in Neurodegeneration” This seminar has been recorded at Area Science Park Trieste by ICGEB Trieste

Davide Trotti, Department of Neuroscience & Farber Institute for Neuroscience, Thomas Jefferson University, Philadelphia - USA speaks on "Neuronal toxicity of the ALS/FTD-linked GGGGCC repeat expansions within the C9ORF72 gene - RNA Metabolism: Changing Paradigms in Neurodegeneration” This seminar has been recorded at Area Science Park Trieste by ICGEB Trieste

Robert Baloh, Cedars-Sinai, Director, Neuromuscular Medicine, ALS Program, Neurodegenerative Diseases Laboratory, Advanced Health Sciences Pavilion Los Angeles - USA speaks on "Cellular and animal models to understand C9ORF72 repeat expansion in ALS and FTLD - RNA Metabolism: Changing Paradigms in Neurodegeneration” This seminar has been recorded at Area Science Park Trieste by ICGEB Trieste

Stuart Pickering-Brown, Professor of Neurogenetics and MRC Senior Research Fellow, Institute of Brain, Behaviour and Mental Health, University of Manchester, Manchester - UK speaks on "Cellular modeling of the C9orf72 repeat expansion - RNA Metabolism: Changing Paradigms in Neurodegeneration” This seminar has been recorded at Area Science Park Trieste by ICGEB Trieste

Boris Rogelj, Department of Biotechnology B3, Jozef Stefan Institute, Ljubljana - SLOVENIA speaks on "RNA-binding proteins that bind ALS- and FTLD-associated hexanucleotide repeat expansion mutation. This seminar has been recorded at Area Science Park Trieste by ICGEB Trieste

Dina Morshedi, National Institute of Genetic Engineering and Biotechnology, Department of Industrial & Environmental Biotechnology, Tehran - IRAN. This seminar has been recorded at Area Science Park Trieste by ICGEB Trieste

Tatyana Shelkovnikova, School of Biosciences, Sir Martin Evans Building, Cardiff - UK speaks on "Multistep process of FUS aggregation in the cell cytoplasm involves RNA-dependent and RNA-independent mechanisms- RNA Metabolism: Changing Paradigms in Neurodegeneration” This seminar has been recorded at Area Science Park Trieste by ICGEB Trieste

Patrizia Longone, Laboratory Head, Fondazione Santa Lucia - Molecular Neurobiology, Rome - ITALY speaks on "Activity-dependent expression of heterogeneous nuclear ribonucleoprotein (hnRNP) mRNAs in neurons: regulated translation at the synapse - RNA Metabolism: Changing Paradigms in Neurodegeneration” This seminar has been recorded at Area Science Park Trieste by ICGEB Trieste

Clotilde Lagier-Tourenne, Assistant Investigator, Ludwig Institute for Cancer Research, Assistant Professor, Department of Neurosciences, University of California, San Diego, La Jolla - USA - speaks on "Targeted degradation of sense and antisense C9orf72 RNA foci as therapy for ALS and frontotemporal degeneration - RNA Metabolism: Changing Paradigms in Neurodegeneration” This seminar has been recorded at Area Science Park Trieste by ICGEB Trieste

Kevin Talbot, Nuffield Department of Clinical Neurosciences, Medical Sciences Division, John Radcliffe Hospital, University of Oxford - UK speaks on Physiological models of TDP-43 related amyotrophic lateral sclerosis - RNA Metabolism: Changing Paradigms in Neurodegeneration" This seminar has been recorded at Area Science Park Trieste by ICGEB Trieste

Abraham Acevedo Arozena, MRC Harwell, Harwell Science and Innovation Campus, Oxfordshire - UK speaks on "Missense mutations in mouse Tardbp differentially affect TDP43 functions - RNA Metabolism: Changing Paradigms in Neurodegeneration". This seminar has been recorded at Area Science Park Trieste by ICGEB Trieste

Bettina Schmid, German Center for Neurodegenerative Diseases(DZNE), Munich - GERMANY speaks on "In vivo function of TDP-43 in zebrafish - RNA Metabolism: Changing Paradigms in Neurodegeneration".This seminar has been recorded at Area Science Park Trieste by ICGEB Trieste

Lionel Muller-Igaz Principal Investigator (CONICET), Neuronal Physiopathology Laboratory, Physiology Departament, School of Medicine, University of Buenos Aires, Buenos Aires - ARGENTINA speaks on "Reversible behavioral phenotypes in a conditional mouse model of TDP-43 proteinopathies - RNA Metabolism: Changing Paradigms in Neurodegeneration".This seminar has been recorded at Area Science Park Trieste by ICGEB Trieste

Eva So, Kings’ College, Department of Clinical Neuroscience, Institute of Psychiatry, DeCreso, London - UK speaks on "An emerging role of FUS at the neuromuscular junction: implications for ALS and FTD pathogenesis". This seminar has been recorded at Area Science Park Trieste by ICGEB Trieste

Lorenzo Errichelli, Selargius (CA) ITALY speaks on "Role of 3’UTR of FUS in Amyotrophic Lateral Sclerosis disease".This seminar has been recorded at ICTP Trieste by ICGEB Trieste

Emanuele Buratti, Molecular Pathology Group Leader, ICGEB Trieste - ITALY speaks on "New insights on TDP-43 structural and splicing processes - RNA Metabolism: Changing Paradigms in Neurodegeneration". This seminar has been recorded at Area Science Park Trieste by ICGEB Trieste

Dorothee Dormann, Ludwig Maximilians Universität München, Adolf Butenandt Institute, Metabolic Biochemistry, Munich - GERMANY speaks on "RNA-binding proteins with prion-like domains in neurodegenerative diseases “RNA Metabolism: Changing Paradigms in Neurodegeneration” This seminar has been recorded at Area Science Park Trieste by ICGEB Trieste

Philipp Kahle, Functional Neurogenetics, Department of Neurodegeneration, Hertie Institute for Clinical Brain Research and German Center for Neurodegenerative Diseases, Faculty of Medicine, University of Tübingen - GERMANY speaks on "UBE2E ubiquitin-conjugating enzymes and ubiquitin isopeptidase Y regulate TDP-43 ubiquitinylation - RNA Metabolism: Changing Paradigms in Neurodegeneration”. This seminar has been recorded at Area Science Park Trieste by ICGEB Trieste

Francisco E. Baralle, Molecular Pathology Group, ICGEB Trieste - ITALY speaks on "New insights in TDP-43 aggregation processes - RNA Metabolism: Changing Paradigms in Neurodegeneration”. This seminar has been recorded at Area Science Park Trieste by ICGEB Trieste

Vincenzo Silani, Istituto Auxologico Italiano, U.O. Neurologia – Stroke Unit e Laboratorio Neuroscienze, Milano - ITALY speaks on "From TARDBP and FUS/TLS to C9orf72 in ALS/FTD: further changing paradigms in the genotype-phenotype correlation - RNA Metabolism: Changing Paradigms in Neurodegeneration". This seminar has been recorded at Area Science Park Trieste by ICGEB Trieste

Antonella Alberici, A.O. Spedali Civili di Brescia, U.O. Neurologia 2, Brescia, - ITALY speaks on "Clinical and neuroimaging phenotypes in monogenic FTLD - RNA Metabolism: Changing Paradigms in Neurodegeneration". This seminar has been recorded at Area Science Park Trieste by ICGEB Trieste

Aaron Gitler, Department of Genetics, Stanford University School of Medicine, Stanford - USA speaks on "RNA-binding proteins with prion-like domains in neurodegenerative diseases - RNA Metabolism: Changing Paradigms in Neurodegeneration".This seminar has been recorded at Area Science Park Trieste by ICGEB Trieste