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The Ultimate Asset

PODCAST · health

The Ultimate Asset

Welcome to The Ultimate Asset, powered by Velocity Health. In this podcast, Dr. Sandeep “Dr. Deep” Palakodeti sits down with world-class physicians, health coaches, and high-performing executives to dive deep into what it really takes to feel, look, and perform at your best. These conversations are rooted in the belief that truly transformative healthcare is about diving into the core of who we are as individuals, from our biology to our history, our culture, and our aspirations for the future.

  1. 16

    The ROI of High Performance: Connecting Health, Wealth, and Longevity

    Is it possible to build a "Unicorn" company without destroying your physical health in the process?In this episode of The Ultimate Asset, Dr. Sandeep Palakodeti and Brock Reichert sit down with global entrepreneur and investor Danny Cortenraede. Danny has built a career at the intersection of sports, tech, and capital—scaling the world's largest soccer community, 433, and now leading InStudio Ventures, where he invests in premium assets like the NFL, NBA, and Formula One.Danny shares his "Ultimate Asset" philosophy: treating your health with the same due diligence, investment, and risk management strategies used for a billion-dollar startup. We dive into why the "smart money" is moving toward deep-tech health and how technologies like Springbok Analytics are democratizing elite performance tools for the general public.In this episode, we cover:The "Jockey" vs. The "Horse": Why the personality and resilience of a founder are more important than the business model when identifying a "Unicorn".Energy vs. Time Management: How elite performers manage physical energy to avoid "redlining" in high-pressure global environments.Deep-Tech Longevity: A deep dive into Springbok Analytics and how AI-mapped muscle data is revolutionizing injury prevention and recovery.The "Boring" Work of High Performance: Why non-negotiable anchor habits—like consistent sleep, morning sunlight, and structured recovery—are the true drivers of peak performance.The Athlete’s Transition: What executives can learn from the locker room about mental resilience and maintaining discipline after the "scoreboard" stops watching.Rapid-Fire Investment Logic: Danny’s take on the highest ROI longevity habits and the one wearable he’d bring to a deserted island.Whether you are a founder navigating hustle culture or a high-performer looking to ensure your physical "payout" at age 80 is as high as your financial one, this conversation provides the playbook for building a sustainable, high-impact life.Resources Mentioned:Danny Cortenraede Website: https://dannycortenraede.com/InStudio Ventures: https://instudioventures.com/Danny Cortenraede IG: https://www.instagram.com/dannycortenraede/Connect with Velocity Health:The Ultimate Asset Book: https://a.co/d/03lj4BhIAccelerate Newsletter: http://www.velocityhealthclinic.com/newsletterInstagram: https://www.instagram.com/velocity_health/Twitter/X: https://x.com/join_velocityPrecision Medicine Consults: https://velocityhealthclinic.com/book-your-private-consultation/Disclaimer: This podcast is for educational and informational purposes only and does not constitute medical or investment advice.

  2. 15

    The Leaky Gums Epidemic: How Oral Pathogens Drive Alzheimer's and Heart Disease

    Can your mouth predict your risk for Alzheimer’s, heart disease, or colorectal cancer?In this episode of The Ultimate Asset, Dr. Sandeep Palakodeti sits down with functional dentist Dr. Ilon Choai—known to his followers as Gator—to bridge the critical gap between oral health and systemic medicine.Dr. Ilon explains why the traditional "drill, bill, and fill" model is failing patients and how the mouth serves as the true start of the gut. We explore the "leaky gums" theory and the dangerous translocation of pathogens like P. gingivalis from the mouth to the brain and heart.In this episode, we cover:Salivary Diagnostics: How PCR testing can quantify your risk for chronic disease before symptoms appear.The Nitric Oxide Trap: Why using antiseptic mouthwash could be driving up your blood pressure by nuking beneficial bacteria.The Future of Oral Care: The science of Hydroxyapatite, a NASA-inspired, non-toxic alternative to fluoride that remineralizes enamel through biomimicry.The Oral-Gut Axis: Understanding how oral dysbiosis mirrors leaky gut and systemic inflammation.Rapid-Fire Dental Truths: Dr. Ilon’s take on tongue scraping, the "smell test" for flossing, and why some cavities can actually be reversed without a drill.Whether you are a clinician looking to break out of your medical silo or a high-performer wanting to optimize your longevity, this conversation provides the framework to turn oral health into a proactive pillar of your wellness strategy.Resources Mentioned:Ilon X: https://x.com/thenobsdentistIlon IG: https://www.instagram.com/thenobsdentistNOBS toothpaste: https://nobsroutines.com/Connect with Velocity Health:* Accelerate Newsletter: http://www.velocityhealthclinic.com/newsletter* Instagram: https://www.instagram.com/velocity_health/* Twitter/X: https://x.com/join_velocity* Precision Medicine Consults: https://velocityhealthclinic.com/book-your-private-consultation/Disclaimer: This podcast is for educational and informational purposes only and does not constitute medical or dental advice. Functional dentistry and oral microbiome treatments are specialized clinical approaches that should be managed under the supervision of a licensed dental professional. Always consult with your dentist or physician regarding oral health, systemic inflammation, and cardiovascular risk management.Hashtags:#FunctionalDentistry #OralMicrobiome #Longevity #SystemicHealth #TheUltimateAsset #NitricOxide #DentalHealth #Biohacking #PrecisionMedicine #OralHealth

  3. 14

    The Science of Ovarian Longevity: How Your Hormones Control Aging with Dr. Brittany Busse MD

    Most women are told that the symptoms of menopause and systemic fatigue are "just part of the journey." In this episode of The Ultimate Asset, Dr. Brittany Busse and Hallie Abrams return to debunk the reactive medical model that ignores the unique biological timeline of women and reveal how prioritizing ovarian health can transform your longevity.We move past the "15-minute doctor visit" to explore how the ovaries act as the "canary in the coal mine" for a woman’s entire body. Dr. Bussey explains why the traditional system is designed for you not to participate and how a whole-person, digital-first approach is the key to breaking the cycle of "pills and diseases."In this episode, we deep-dive into:The Ovarian Longevity Mystery: Why the ovary is the only organ that "wears out" decades before the rest of the body—and the "mind-blowing" research suggesting that extending ovarian health could extend the health-span of every other organ.The Estrobolome & Gut Health: We break down the specific microbiome responsible for estrogen balance. Learn how the "deconjugation of estrogens" in the gut leads to skin rashes, thyroid issues, and heightened menopausal symptoms.Escaping the "Medication Spiral": Why the current healthcare system often leads to a cycle of taking one medication to treat the side effects of another, and how to reclaim your agency as a patient.The Research Gap: A candid look at why women were historically excluded from medical research due to hormonal "fluctuations" and how that data gap still affects your care today.The Digital Health Revolution: Why a virtual, collaborative medical experience often provides more comprehensive care than traditional in-person specialist visits.Personalized Data vs. General Advice: Why understanding your specific parameters is the only way to move from "surviving" to "thriving" during the hormonal transition.Ready to stop guessing? Join our research newsletter, Accelerate, to get the latest scientific deep dives on longevity delivered to your inbox: http://www.velocityhealthclinic.com/newsletterResources Mentioned:https://velocityhealthclinic.com/hallie-abrams/https://www.instagram.com/thewardrobeconsultant/Connect with Velocity Health:Instagram: https://www.instagram.com/velocity_health/Twitter/X: https://x.com/join_velocityPrecision Medicine Consults: https://velocityhealthclinic.com/book-your-private-consultation/Disclaimer: This podcast is for educational and informational purposes only and does not constitute medical advice. Hormone Replacement Therapy (HRT) and precision medicine protocols are regulated medical treatments that require professional supervision and a valid prescription. Always consult with a qualified medical professional regarding menopause transition, hormonal optimization, and metabolic health treatment.

  4. 13

    The Systems Approach to Women’s Health: HRT, Gut Health, and Reversing "Skinny Fat"

    Most women are told that the symptoms of perimenopause and aging are "just part of the journey." In this episode of The Ultimate Asset, Dr. Brittany Busse and Hallie Abrams debunk the reactive, "cookie-cutter" medical model and reveal how high-performance medicine can restore vibrancy at any age.We move past the "Dr. Google" rabbit hole to explore how hormones, gut health, and muscle mass are deeply interconnected. Dr. Busse explains why a one-size-fits-all protocol fails and how individualized data, from GI mapping to DEXA scans, is the key to proactive health management.In this episode, we deep-dive into:The HRT Revolution: The critical difference between synthetic birth control and bioidentical Estradiol and Progesterone. We discuss the "Hormonal Chaos" of perimenopause and how to safely navigate hormone replacement therapy (HRT).The Gut-Autoimmune Axis: Why "anti-thyroid" antibodies often start in the gut. We break down short-chain fatty acids (like Butyrate) and why the type of fiber you take determines your cholesterol and estrogen clearance.The "Skinny Fat" Epidemic: Why your weight might be fine, but your Appendicular Lean Mass Index (ALMI) is dangerously low. We explain how muscle acts as an "insulin sponge" to reverse insulin resistance and metabolic dysfunction.Preventative Vaginal Health: A candid conversation on why vaginal estrogen is the "preventative eye cream" for your pelvic health, preventing UTIs and tissue breakdown.Axial Loading for Bone Density: Why heavy lifting (squats, deadlifts, and the Smith machine) is non-negotiable for women over 40 to protect against fractures.Precision Fat Loss: A medical perspective on 3rd-generation peptides like Retatrutide and how to use them without sacrificing hard-earned muscle mass.Sleep & Cortisol: How to manage the 3:00 AM wake-up call and why Melatonin might be ruining your sleep architecture.Ready to stop guessing? Join our research newsletter, Accelerate, to get the latest scientific deep dives on longevity delivered to your inbox: www.velocityhealthclinic.com/newsletterResources Mentioned:* https://velocityhealthclinic.com/hallie-abrams/* https://www.instagram.com/thewardrobeconsultant/Connect with Velocity Health:* Instagram: https://www.instagram.com/velocity_health/* Twitter/X: https://x.com/join_velocity* Precision Medicine Consults: https://velocityhealthclinic.com/book-your-private-consultation/Disclaimer: This podcast is for educational and informational purposes only and does not constitute medical advice. Hormone Replacement Therapy (HRT) and peptides are regulated medical treatments that require professional supervision and a valid prescription. Always consult with a qualified medical professional regarding menopause transition, hormonal optimization, and metabolic health treatment.

  5. 12

    How Psilocybin Healed My Traumatic Brain Injury: Ex-NHL Pro Kyle Quincey

    Can "Original Medicine" solve the Traumatic Brain Injury (TBI) crisis facing our athletes and veterans?In this episode of The Ultimate Asset, we sit down with Kyle Quincey, a 13-year NHL veteran (Detroit Red Wings, LA Kings, Colorado Avalanche) who walked away from the game with 20+ concussions and a crumbling sense of identity.Kyle pulls back the curtain on the "old school" NHL culture, where survival meant a lethal cocktail of alcohol, anti-inflammatories and Ambien provided by the team. He shares his raw journey from the brink of despair to finding profound healing through a high-dose psilocybin "hero journey" that changed his brain and his life forever.Now the founder of Do Good Ranch in Crawford, Colorado, Kyle is recreating the "locker room" for veterans, first responders, and elite performers using nature, sunlight, community, and sacred medicine.In this episode, we discuss:The NHL Medical Myth: Why "Little Caesar's pizza and diners" was the standard for elite performance nutrition.Playing Through Pain: What it’s really like to play in the NHL with one leg and a broken face.The TBI Epidemic: Why athletes and Special Forces operators face the same "loss of purpose" after service.The Science of Psilocybin: How a 6-hour journey acted like a "mechanic under the hood" for Kyle’s brain.Do Good Ranch: The "personal use" model of Colorado Prop 122 and why nature is the ultimate teacher.About Kyle Quincey: Kyle Quincey is a 13-year NHL veteran who played for teams including the Detroit Red Wings and Colorado Avalanche. Following his retirement, he dedicated his life to brain health advocacy and founded the Do Good Ranch, a retreat center focused on healing TBI for the "brotherhood" of heroesResources Mentioned:Do Good Ranch: dogoodranch.comColorado Prop 122 (Natural Medicines Act)Kylequincey.com Connect with Velocity Health:Accelerate Newsletter: www.velocityhealthclinic.com/newsletterInstagram: https://www.instagram.com/velocity_health/Twitter/X: https://x.com/join_velocityPrecision Medicine Consults:   https://velocityhealthclinic.com/book-your-private-consultation/Disclaimer: This podcast is for educational and informational purposes only. Psychedelic substances are illegal in many jurisdictions. Always consult with a medical professional regarding Traumatic Brain Injury and mental health treatment.#NHL #KyleQuincey #TBI #BrainHealth #Psilocybin #VeteranHealth #DoGoodRanch #TheUltimateAsset #CTE #PsychedelicMedicine #ColoradoHealth

  6. 11

    Does EMF Impact Athletic Performance? NFL Injuries & Quantum Biology Explained

    Is an "invisible pathogen" causing the surge in NFL soft-tissue injuries? In this episode of The Ultimate Asset, we sit down with Peter Cowan, the author of the viral thread exploring the 49ers' injury cluster, and Pratik Patel, former Director of Performance Nutrition and Assistant Strength Coach for the New York Giants.We move past the "conspiracy theorist" labels to discuss the biologically defensible mechanisms of how electromagnetic fields (EMF), "dirty electricity," and artificial light environments impact human physiology at the top of performance. From voltage-gated calcium channels to mitochondrial water production, we explore why recovery is more than just sleep and nutrition, it’s about your Quantum Environment.In this episode, we discuss:The 49ers Substation Mystery: The expansion of the Santa Clara substation and its proximity to elite training facilities.The Mechanistic Proof: How EMF triggers voltage-gated calcium channels (VGCCs), leading to oxidative stress and impaired collagen repair.Inside the NFL Locker Room: Pratik Patel shares what elite athletes are actually asking about; from grounding and red light to ozone therapy and EMF shielding.The "Dirty Electricity" Problem: Why high-frequency transients in the ground might be the "straw that breaks the camel's back" for an athlete's Achilles or ACL.Circadian Lighting: Why 5000K LEDs are the #1 environmental pollutant in most modern homes and facilities.The Top 3 Injured Teams: A new analysis of man-games missed in 2025 and their proximity to major power substations.About Our Guests: Peter Cowan is a quantum biology practitioner and founder of Sunlight Is Life. Pratik Patel spent over a decade in collegiate and elite sports (NFL/Giants) and is the founder of Blueprxnt.Connect with Our Guests:Peter Cowan: SunlightIsLife.com | Twitter: @living_energyPratik Patel: [Blueprxnt] | Twitter: @PratikXPatelConnect with Velocity Health:Accelerate Newsletter: http://www.velocityhealthclinic.com/newsletterInstagram:https://www.instagram.com/velocity_health/Twitter/X: https://x.com/join_velocityPrecision Medicine Consults: https://velocityhealthclinic.com/book-your-private-consultation/Disclaimer: This podcast is for informational purposes only and does not claim a definitive causal link between specific substations and injuries. It is an exploration of biological plausibility and the need for further research in environmental health.#NFL #49ers #EMF #QuantumBiology #Longevity #Biohacking #SportsMedicine #Mitochondria #CircadianRhythm #TheUltimateAsset

  7. 10

    Beyond "Sick Care": Precision Medicine and the Future of Longevity with Dr. Brian Cornblatt

    Is the modern medical system designed to keep you sick?In this powerful episode of The Ultimate Asset, Dr. Deep is joined by Dr. Brian Cornblatt, a PhD researcher and leader in the field of genomic longevity. Dr. Cornblatt shares his extraordinary transition from a Johns Hopkins pediatric oncology researcher to a pioneer in precision medicine. His journey was sparked by diagnosing his own father with metastatic cancer and later uncovering his own medical misdiagnosis.Dr. Cornblatt pulls no punches on the "Sick Care" model, revealing a shocking 25-year trend in colorectal cancer and why standard protocols are failing the younger generation. We travel (virtually) to the new Quantum Longevity AI center in the Bahamas to explore the futuristic therapies currently unavailable in the U.S.In this episode, we discuss:The Johns Hopkins Data: Why colorectal cancer in patients under 50 has jumped from 10% to over 50% in just two decades.The Power of Sulforaphane: The science behind broccoli sprouts and how they supported Dr. Cornblatt’s father’s 30-year survival story.Precision vs. Allopathic Medicine: Why treating every tumor with the same drug is outdated and how full genomic screening changes the game.Limb Salvage & Regenerative Care: How Quantum is using exosomes, red light therapy, and oxygenation to reverse diabetic ulcers and prevent amputations.The 12,000-Year Rule: Why our genetics haven't caught up to modern "factory farm" food and how to eat for your DNA.The Bahamas Frontier: Understanding the LARTA Act and why the Bahamas is becoming the global destination for regenerative medicine.About Dr. Brian Cornblatt: Dr. Cornblatt is the Director of Precision and Personalized Medicine at Quantum Longevity AI. With a background in molecular research from Johns Hopkins and a career dedicated to translational science, he is at the forefront of integrating AI with human biology to extend both lifespan and "love span."Resources Mentioned:Quantum Longevity AI (Bahamas)Clinicaltrials.gov (Search: Avmacol / Dr. Brian Cornblatt)The Vogelgram (Genetic Mapping of Cancer)Whole30 Nutrition ProgramConnect with Velocity Health:Accelerate Newsletter: www.velocityhealthclinic.com/newsletterWebsite:https://www.velocityhealthclinic.comInstagram: https://www.instagram.com/velocity_health/Twitter/X: https://x.com/join_velocityPrecision Medicine Consults: https://velocityhealthclinic.com/book-your-private-consultation/Disclaimer: This video is for educational purposes only and does not constitute medical advice. Consult with a qualified healthcare provider before beginning new treatments.

  8. 9

    The Peptide King: Optimizing Immunity, Recovery, and Mitochondrial Health // Anthony Castore

    In this episode of The Ultimate Asset, host Brock Reichert is joined by Anthony Castore, known in the industry as "The Peptide King." Anthony is the first non-physician fellow of the SSRP (Seeds Scientific Research and Performance) Institute and creator of the CASTORE Method.Together, they demystify the complex world of peptides, moving beyond the buzzwords to explain how these signaling molecules actually work within the body. From navigating the "flu season" with immune-modulating protocols to recovering from injuries for elite athletic performance, this episode covers the foundational pillars of cellular medicine.Anthony also opens up about a personal medical emergency caused by improper peptide stacking, offering a cautionary tale on why foundational health (Redox) must come before biohacking. Whether you are an athlete training for a race like Leadville 100 or simply looking to improve your health span, this conversation provides actionable insights into metabolic optimization.Key Topics & TakeawaysPeptides 101: Understanding peptides as "signaling molecules" (CEOs giving directions to interns) rather than magic bulletsThe CASTORE Method: A breakdown of Anthony’s coaching pyramid: Coaching, Advanced Scientific Targeted Optimization, Recovery, and Exercise.The Importance of Redox: Why you must optimize your body's "soil" (oxidative stress modulation) before planting the "seeds" (peptides).Cautionary Tales: Anthony shares his personal horror story of hospitalization due to peptide overloading and signal noise.Immune System Optimization:Why Thymosin Alpha-1 is the "OG" of immune modulation.Protocols for flu season, including the surprising benefits of low-dose nicotine and ketone monoesters.Injury Recovery & Joint Health: The differences between TB-500 and Thymosin Beta-4, and the use of BPC-157 and Pentosan Polysulfate for cartilage regeneration.Mitochondrial Health: Deep dive into SS-31 for repairing the "scaffolding" of energy production.Featured Peptides & Supplements MentionedImmune & Repair: Thymosin Alpha-1, BPC-157, LL-37.Mitochondrial: SS-31, MOT-c.Injury/Joints: Thymosin Beta-4 (vs. TB-500 fragments), Pentosan Polysulfate.Supplements: Ketone Monoesters (KE4/Kinetic Pro), Phospholipids/Plasmalogens.Connect with Anthony CastoreCommunity: https://www.skool.com/castore-built-to-adapt-7414Instagram: @AnthonyCastoreThis podcast is for informational purposes only and does not constitute medical advice. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition or new health protocol.

  9. 8

    VO2 Max vs. Zone 2: Why You Need Sprinting for Longevity

    When was the last time you ran as fast as you possibly could? For most adults over 30, the answer is "not in the last year." In this mini-episode of The Ultimate Asset, Dr. Deep and Brock Reichert break down the science of Sprint Interval Training (SIT) and why it is a non-negotiable pillar of high-performance medicine. While "Zone 2" cardio is essential for building an aerobic base, you cannot maximize your VO2 Max (one of the highest correlates to overall longevity) without pushing into Zone 5.*In this episode, you’ll discover:** The Sprinting Ladder: Brock’s routine for layering distances (100m to 400m) to push through the "death zone."* VO2 Max & Longevity: Why this metric is the ultimate indicator of cardiac output, mitochondrial health, and vascular efficiency.* The Secret Hypertrophy Benefit: How explosive force recruits fast-twitch fibers and releases growth hormone.* RPE (Rate of Perceived Exertion): Why an 8 or 9 out of 10 is the "sweet spot" for training without snapping a hamstring.* The Mental High: The role of BDNF (Brain-Derived Neurotrophic Factor) in reducing anxiety and depression through high-intensity work.* Programming for Executives: How to balance 3 hours of Zone 2 with high-intensity intervals for maximum efficiency.* What is a good VO2 Max? Dr. Deep explains what to expect during a clinical VO2 Max test and why you should aim for the "elite" category relative to your age group.*Connect with Velocity Health:** Website: https://www.velocityhealthclinic.com* Instagram: https://www.instagram.com/velocity_health/* Twitter/X: https://x.com/join_velocity* Precision Medicine Consults: https://velocityhealthclinic.com/book-your-private-consultation/Disclaimer: This video is for educational purposes only. High-intensity sprinting carries an injury risk. Please consult with a physician and ensure a proper warm-up before attempting RPE 8+ efforts.#VO2Max #Sprinting #Longevity #Zone2Cardio #HighPerformanceMedicine #TheUltimateAsset #FitnessScience #Biohacking #IntervalTraining #HealthOptimization

  10. 7

    Reversing Vascular Plaque: The Truth About Cholesterol with Lipidologist Dr. William Cromwell

    Heart disease is the #1 killer in the world, but are we measuring the right markers?In this episode of The Ultimate Asset, Dr. Deep sits down with Dr. William Cromwell, a world-renowned lipidologist and Chief Medical Officer of Precision Health Reports. With over three decades of experience, Dr. Cromwell breaks down why the traditional "calculated LDL" economy is failing patients and why we must look at the actual ApoB particle count to understand vascular risk.We explore the "perfect storm" of cardiometabolic disease—the intersection of insulin resistance, systemic inflammation, and atherogenic lipoproteins. Dr. Cromwell also reveals the LPIR score, a groundbreaking biomarker that can predict type 2 diabetes up to 20 years before blood sugar levels ever rise.*In this episode, we discuss:** The Cholesterol Economy: Why LDL-C is an outdated surrogate and how ApoB provides the true "bottle count" of risk.* Atherosclerosis 101: How particles penetrate the subendothelial layer and transform into foam cells.* The LPIR Score: Why this NMR-derived metric is the most powerful predictor of insulin resistance and incident diabetes.* Imaging Over Labs: Why a CAC score of zero can be a "false negative" and how CCTA or Carotid Ultrasound find the plaque that matters.* Lipoprotein(a): The genetic "poor hand" and why you only need to test it once in a lifetime.* Statin Intolerance: Creative ways to manage risk through combination therapy and the "Rule of Sixes."* The MVX & GlycA Scores: New ways to discriminate mortality risk independent of age or existing vascular disease.About Dr. William Cromwell: Dr. Cromwell is an Associate Professor of Lipidology at Wake Forest and a leading thinker in personalized medicine. His work focuses on integrating clinical history with advanced biomarkers to create highly individualized risk assessments.*Resources Mentioned:** Precision Health Reports: precisionhealthreports.com* MESA Study (Multi-Ethnic Study of Atherosclerosis)* Framingham Heart Study* CIMT vs. B-mode Ultrasound*Connect with Velocity Health:** Website: https://www.velocityhealthclinic.com* Instagram: https://www.instagram.com/velocity_health/* Twitter/X: https://x.com/join_velocity* Precision Medicine Consults: https://velocityhealthclinic.com/book-your-private-consultation/Disclaimer: This video is for educational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider regarding your specific health concerns.#HeartHealth #Lipidology #ApoB #InsulinResistance #Longevity #PrecisionMedicine #DrWilliamCromwell #Cholesterol #Biohacking #DiabetesPrevention #TheUltimateAsset

  11. 6

    Reversing Heart Disease: The Science of LDL and Lipoprotein(a) with Dr. Steven Nissen

    Heart disease remains the #1 killer worldwide, but are we doing enough to prevent it?In this episode of The Ultimate Asset, Dr. Deep sits down with Dr. Steven Nissen, Chief Academic Officer of the Heart and Vascular Institute at the Cleveland Clinic and one of the most influential cardiologists in medical history. Dr. Nissen has led the landmark trials that changed the way the FDA approves drugs and how we treat cholesterol today.We dive deep into the "Lower for Longer" philosophy, the truth about statin denialism, and the groundbreaking new therapies for Lipoprotein(a)—a genetic risk factor that traditional tests often miss.In this episode, we discuss:* The Traverse Trial: The real impact of Testosterone Replacement Therapy (TRT) on heart health.* Vioxx & Avandia: The "Good Trouble" Dr. Nissen got into while exposing dangerous drug side effects and forcing FDA transparency.* The Reversal & Asteroid Trials: Can you actually regress coronary plaque? The data on intensive LDL lowering.* Lipoprotein(a) Explained: Why this "noxious particle" is 3-6x more atherogenic than standard LDL and how new RNA-interference drugs are aiming for a 95% reduction.* Statin Denialism: Addressing the "Internet cults" and why evidence-based medicine remains the gold standard for saving lives.* The 77-Year-Old Work Ethic: Dr. Nissen shares his personal health "stack" for longevity, including his take on supplements vs. pharmaceutical prevention.*About Dr. Steven Nissen:* Dr. Nissen is a world-renowned cardiologist, researcher, and patient advocate. His work has been instrumental in establishing the requirement for cardiovascular outcome trials (CVOT) for new medications, ensuring patient safety across the globe.Resources Mentioned:* The Traverse Trial (TRT Safety)* The Reversal Trial (Plaque Regression)* The SPORT Trial (Dietary Supplements vs. Statins)* Clinicaltrials.govConnect with Velocity Health:Website: www.velocityhealthclinic.comInstagram: https://www.instagram.com/velocity_health/Twitter/X: https://x.com/join_velocityPrecision Medicine Consults: https://velocityhealthclinic.com/book-your-private-consultation/Disclaimer: This video is for educational purposes only and does not constitute medical advice. Always consult with your physician before starting new medications or supplements.#HeartHealth #Cardiology #DrStevenNissen #LDL #LipoproteinA #Statins #Longevity #PrecisionMedicine #ClevelandClinic #HeartDiseasePrevention

  12. 5

    The Future of Women’s Health: Precision Medicine, HRT Myths & “Love Span” - Dr. Busse, Dr. Chambers

    In this power-packed episode for Women’s Health Month, Dr. Sandeep Palakodeti sits down with precision medicine experts Dr. Brittany Busse &Dr. Ashley Chambers to dismantle the "one-size-fits-all" approach to female physiology. They explore why women have been historically excluded from medical research and how the modern medical system often dismisses women's symptoms as "histrionics" or "anxiety."The doctors dive deep into the complexities of the perimenopause transition, the truth behind the controversial Women's Health Initiative (WHI) study, and why "women are not just men without penises". From the "Bean Diet" for estrogen metabolism to the nuances of bioidentical hormone replacement therapy (BHRT), this episode provides a roadmap for women to reclaim their health span and vitality.*Chapters** 00:00 Introduction to Women's Health and Precision Medicine* 02:30 The Importance of Understanding Women's Unique Health Needs* 08:58 Research Gaps in Women's Health* 11:19 Clinical Practice: Recognizing Women's Health Issues* 17:24 Hormonal Management and Therapy* 20:51 Family Planning and Fertility Optimization* 28:02 Navigating Perimenopause Symptoms* 35:03 Hormone Replacement Therapy: Myths and Realities* 39:52 Understanding Estrogen Replacement Therapy* 42:40 Bioidentical vs. Synthetic Hormones* 44:37 The Role of Testosterone in Women's Health* 51:35 Monitoring Hormone Therapy Effectiveness* 55:19 The Future of Women's Health and Medicine*Key Topics & Takeaways** The Gender Data Gap: Why the 1977 FDA rule excluding women from research created a 20-year dearth of data that still affects clinical care today.* Cardiovascular Health in Women: Why a Coronary Artery Calcium (CAC) score of zero might be a false sense of security for perimenopausal women. The role of CCTA (Coronary Computed Tomography Angiography) in finding soft, unstable plaque.* The Hormone Journey: Perimenopause: Recognizing the first sign—the feeling of "not feeling like myself"—which can start 10 years before menopause. Estrogen Receptors: How estrogen impacts every tissue, from the brain and heart to bones and skin.* Hormone Replacement Therapy (HRT) Debunked: Unpacking the flaws of the WHI study and why bioidentical transdermal patches are the modern gold standard. The "Wild West" of testosterone pellets: Why women should run from providers who "put pellets in everybody".* The "Bean Diet": How soluble fiber (legumes) prevents the enterohepatic circulation of excess hormones and toxins.*Featured Resources & Mentions** The Women's Health Initiative (WHI): A critical look at the study that scared a generation away from HRT.* Menopause Society Guidelines: Current standards for birth control vs. HRT in the 40s and 50s.* Lisa Moscone: Research on the female brain and estrogen withdrawal.* The "Bean Diet" (Unique Hammond/Karen Hurd): A nutritional strategy for hormone clearance.*Connect with Velocity Health:** Website: https://www.velocityhealthclinic.com* Instagram: https://www.instagram.com/velocity_health/* Twitter/X: https://x.com/join_velocityDisclaimer: This video is for educational purposes only and does not constitute medical advice. Hormone therapy and medical diagnostics should only be pursued under the supervision of a qualified physician.

  13. 4

    3. Testosterone: From Rooster Testicles to Modern Therapy // Dr. Dan Fosselman

    Join Dr. Deep, Brock Reichert, and Dr. Dan Fossilman as they delve into the fascinating world of testosterone optimization therapy. Did you know testosterone was once isolated from rooster testicles? Discover the shocking history and modern insights in our latest episode! This episode explores the decline in testosterone levels, the impact of lifestyle on hormone health, and the myths surrounding testosterone replacement therapy. Is low testosterone a real epidemic or just clever marketing? Uncover the truth with our expert panel! From crushed animal testicles to cutting-edge therapy—explore the wild journey of testosterone! Tune in for an engaging discussion that challenges conventional wisdom and offers practical advice for optimizing health.To connect and work with us: Velocityhealthclinic.comCitations:https://academic.oup.com/jcem/article-abstract/92/1/196/2598434https://www.sciencedirect.com/science/article/abs/pii/S2405456920300626#Testosterone #HealthOptimization #Podcast

  14. 3

    2. Unlocking Your Best Sleep // Dr. Sahil Chopra

    The episode of the Ultimate Asset is all about optimal sleep. Is tracking sleep the REAL way to measure biologic age? What should we try in order to fix our sleep? and How do we know if we are even tracking our sleep properly? Find out this and more as we talk with world-renowned sleep expert Sahil Chopra, Co-founder of Empower Sleep. To learn more about Velocity Health, visit http://VelocityHealthClinic.com To learn more about Empower Sleep, visit http://Empowersleep.com

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    1. How to Protect Your Brain // Dr. Marc Rothman

    In the premiere episode of The Ultimate Asset, Dr. Sandeep “Dr. Deep” Palakodeti, Morgan Koth, and Brock Reichert tackle one of the most pressing health concerns of our time: brain health and dementia prevention.The team shares personal stories about loved ones who have experienced mental decline, discusses the fear of growing older, and breaks down the science behind Alzheimer’s. They’re joined by nationally respected geriatrician Dr. Marc Rothman, who shares a refreshingly hopeful approach to navigating dementia and provides insight on how to protect your brain from decline.

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ABOUT THIS SHOW

Welcome to The Ultimate Asset, powered by Velocity Health. In this podcast, Dr. Sandeep “Dr. Deep” Palakodeti sits down with world-class physicians, health coaches, and high-performing executives to dive deep into what it really takes to feel, look, and perform at your best. These conversations are rooted in the belief that truly transformative healthcare is about diving into the core of who we are as individuals, from our biology to our history, our culture, and our aspirations for the future.

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Velocity Health

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