#001: "Should I be taking a probiotic?"

Zach and Brandon discuss the evidence for and against using probiotics as treatment for medical diseases and the mechanisms that may confer health benefits to individuals without disease. Subjective: 0:45 - Brandon’s experience at the Metabolic Health Summit 10:19 - Introduction to probiotics 21:38 - Zach and Brandon’s probiotic protocol for themselves 24:25 - Introduction to the microbiome Objective: 32:25 - Probiotics as treatment and prevention for type II diabetes and obesity 45:08 - Treating digestive diseases with probiotics 55:20 - Using probiotics to treat and prevent allergic rhinitis and eczema 57:08 - Probiotics and depression 1:01:06 - Short-chain fatty acid (SCFA) effects on inflammation and innate immunity 1:18:00 - SCFAs and the gut-brain axis 1:24:34 - Insulin and satiety regulation through SCFAs 1:30:45 - Mitigating antibiotic side effects 1:32:30 - What to look for: strains, dosage, viability, timing 1:40:10 - Safety concerns and side effects Assessment/Plan: 1:43:50 - Conclusion, using probiotics for treatment and healthy individuals