#007 - Understanding mechanisms of neonatal pathologies: From Gut to Inflammation

Dr. Steve McElroy, a neonatologist and physician scientist, discusses his research on injury and repair mechanisms in the immature intestine, specifically focusing on necrotizing enterocolitis (NEC) and spontaneous intestinal perforation in premature infants. He shares his journey from initially not wanting to pursue science to becoming a physician scientist, and how mentorship played a crucial role in his career. Dr. McElroy also talks about his pioneering work on Paneth cells and the Paneth cell ablation NEC model. He highlights the importance of listening, asking questions, and being open to new research directions. Finally, he discusses the impact of his leadership role as a division chief on his research and mentorship activities. He emphasizes the importance of mentorship, celebrating small victories, and persisting through challenges. Dr. McElroy also shares insights into his current research on chorioamnionitis and its impact on neonatal health. He highlights the need for creative think time and the value of understanding mechanisms in basic science. The conversation concludes with a discussion on building a supportive and fun lab environment.