012 Treatment Without Transplant: What Older Myeloma Patients Need to Know

Welcome to The Myeloma Minutes.   This episode explores the standard treatment for older or transplant-ineligible patients with myeloma, focusing on the DRD regimen, its side effects, and supportive care options. 📌Key points: The DRD combo (Daratumumab, Lenalidomide, Dexamethasone) can keep myeloma controlled for years—even in older patients. Steroids are powerful but often reduced or stopped early to improve quality of life. You may start with a dozen pills—but many are temporary and can be stopped as treatment progresses. This podcast is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional for personalised medical guidance regarding your health concerns   ABOUT YOUR HOSTS Dr. Jam Kothari Dr Jam Kothari (@myeloma_medic) is an Oxford based blood cancer doctor, specialising in the treatment of multiple myeloma and associated conditions. He has been a consultant for a decade, and leads the provision of myeloma care for Oxford and neighbouring areas. He lectures regionally and nationally and leads clinical trials investigating the use of new treatments for myeloma. He is a strong believer in patient based, holistic care, delivered with warmth, clarity and integrity.   Dr. Sally Moore Dr Sally Moore is a Bristol based consultant who specialises in treating patients living with multiple myeloma and other plasma cell disorders. She oversees the delivery of clinical research studies for myeloma patients and has academic interests in how to maximise quality of life for patients and improve outcomes in older, less fit patients.  She frequently contributes to myeloma related educational events for fellow doctors and healthcare professionals at a local, regional and national level and is an active member of the UK Myeloma Research Alliance and an executive member of the UK Myeloma Society.