1 20 2025

Hi, This Week in Medicine, we will be discussing

New England Journal of Medicine

Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis

APOL1 Bi- and Monoallelic Variants and Chronic Kidney Disease in West Africans

Fracture Prevention with Infrequent Zoledronate in Women 50 to 60 Years of Age

Survival with Trastuzumab Emtansine in Residual HER2-Positive Breast Cancer

 Journal of  American Medical Association

Intra-Arterial Tenecteplase Following Endovascular Reperfusion for Large Vessel Occlusion Acute Ischemic Stroke: The POST-TNK Randomized Clinical Trial

Intra-Arterial Urokinase After Endovascular Reperfusion for Acute Ischemic Stroke: The POST-UK Randomized Clinical Trial

 Annals of Internal Medicine

Inequities in Distance to Lung Cancer Screening Programs

  British Medical Journal

Time to nursing home admission and death in people with dementia

  Lancet

Efficacy, safety, and target engagement of dazukibart, an IFNβ specific monoclonal antibody, in adults with dermatomyositis: a multicentre, double-blind, randomised, placebo-controlled, phase 2 trial

  Journal of Clinical Oncology

Association of Participation in Medicare's Oncology Care Model With Spending, Utilization, and Quality Outcomes Among Commercially Insured and Medicare Advantage Members

  journal of Hepatology

Effect of pemvidutide, a GLP-1/glucagon dual receptor agonist, on MASLD: A randomized, double-blind, placebo-controlled study

Neuropilin-1 is a novel host factor modulating the entry of hepatitis B virus

 Gastroenterology

Unveiling Cancer-Related Metaplastic Cells in Both Helicobacter pylori Infection and Autoimmune Gastritis

  Clinical Gastroenterology

 Satisfaction With and Adherence to Off-Label Corticosteroids in Adolescents and Adults With Eosinophilic Esophagitis: Results of a Web-Based Survey in the United States

Meta-Analysis of Endoscopic Full-Thickness Resection Versus Endoscopic Submucosal Dissection for Complex Colorectal Lesions

 Rheumatology 

Altered Protein Structures and Neoepitopes in Lupus Neutrophils From Dysregulated Splicing of Messenger RNA

  Journal of Clinical Rheumatology 

Nationwide Analysis of Variables Associated With Sarcoid Inpatient Mortality

    Circulation

Sickle Trait and Alpha Thalassemia Increase NOS-Dependent Vasodilation of Human Arteries Through Disruption of Endothelial Hemoglobin-eNOS Interactions

 Journals of the American College of Cardiology

Drug-Coated Balloon Angioplasty of the Side Branch During Provisional Stenting: The Multicenter Randomized DCB-BIF Trial

Aspirin and Hemocompatibility After LVAD Implantation in Patients With Atherosclerotic Vascular Disease

A Secondary Analysis From the ARIES-HM3 Randomized Clinical Trial

  Journal of Clinical Endocrinology & Metabolism

Regional Adiposity and Insulin Sensitivity—Interactions With Menopause and HIV in Middle-Aged Black African Women

  Diabetes care

Combination SGLT2 Inhibitor and Glucagon Receptor Antagonist Therapy in Type 1 Diabetes: A Randomized Clinical Trial 

Here are the  articles   from  Chest

Clinical Characteristics and Prognosis of Patients With Severe Pneumonia With Pneumocystis jirovecii Colonization

Here are the  articles   from The American Journal of Respiratory and Critical Care Medicine

Proteomic Risk Score of Increased Respiratory Susceptibility: A Multicohort Study.

 Clinical Journal of American Society of Nephrology

Surrogate End Points in Apolipoprotein L1–Associated Kidney Disease: Evaluation in Three Cohorts

Medication Burden and Adverse Cardiovascular Events and Death in Patients Treated with Maintenance Hemodialysis: A Nationwide Cohort Study

Kidney International reports

Outcome of Patients Transplanted for C3 Glomerulopathy and Primary Immune Complex-Mediated Membranoproliferative Glomerulonephritis