10 21 2025

Hi, This Week in Medicine, we will be discussing New England Journal of Medicine Sentinel-Lymph-Node Biopsy Alone or with Lymphadenectomy in Cervical Cancer A Phase 3 Trial of Telitacicept for Systemic Lupus Erythematosus Long-Term Safety and Efficacy of Gene Therapy for Adenosine Deaminase Deficiency Mass Administration of Azithromycin to Infants in Mali to Reduce Mortality  Journal of  American Medical AssociationIntra-Arterial Alteplase After Successful Endovascular Reperfusion in Acute StrokeThe PEARL Randomized Clinical TrialAnnals of Internal MedicineEffectiveness of Recombinant Herpes Zoster Vaccine in the U.S. Medicare Population, 2018 to 2019, by Immunocompetence and Prior Receipt of Live Zoster Vaccine British Medical JournalSodium-glucose cotransporter-2 inhibitors and risk of autoimmune rheumatic diseases: population based cohort study  LancetThe global, regional, and national burden of cancer, 1990–2023, with forecasts to 2050: a systematic analysis for the Global Burden of Disease Study 2023 JAMA oncology Pathogenic Variants, Family History, and Cumulative Risk of Breast Cancer in US Women  Gastroenterology Efficacy of ACupuncTure in Irritable bOwel syNdrome (ACTION): A Multicenter Randomized Controlled Trial  Clinical GastroenterologySafety and Efficacy of Endoscopic Submucosal Dissection for Rectal Neoplasms Extending to the Dentate Line: A Systematic Review and Meta-analysis  Clinical Infectious DiseasesDolutegravir/Lamivudine for Maintenance of Virological Suppression in Persons With Historical Suspected or Confirmed Resistance to Lamivudine: Week 48 Results of a Single-Arm, Open-Label, Multicenter, Phase IIa Clinical Trial  Journal of Clinical Rheumatology Knowledge and Behaviors in Reproductive Health Among Mexican Women With Autoimmune Rheumatic Diseases: Cross-sectional Study  CirculationContemporary Burden of Cardiovascular Disease in Pregnancy: Insights From a Real-World Pregnancy Electronic Health Record Cohort  Journals of the American College of CardiologyClonal Hematopoiesis and Cardiovascular Outcomes in Older Women JAMA CardiologyEfficacy and Tolerability of Finerenone According to the Use and Dosage of DiureticsA Prespecified Analysis of the FINEARTS-HF Randomized Clinical Trial Journal of Clinical Endocrinology & MetabolismEvaluation of Aldosterone Suppression by Cinnarizine, a Putative Cav1.3 Inhibitor  ChestThe Association Between Mechanical Power Within the First 24 Hours and ICU Mortality in Mechanically Ventilated Adult Patients With Acute Hypoxemic Respiratory Failure The American Journal of Respiratory and Critical Care MedicineOne-Year Change in Quantitative Computed Tomography Is Associated with Meaningful Outcomes in Fibrotic Lung Disease Clinical Journal of American Society of NephrologyThe Association of Long COVID and CKD: Findings from the National Clinical Cohort Collaborative Kidney International reportsEffects of Combination Treatment on Renal Endothelial Function in Type 2 Diabetes Mellitus