10 27 2025

Hi, This Week in Medicine, we will be discussing New England Journal of Medicine Hypertonic Saline or Carbocisteine in Bronchiectasis Aspirin in Patients with Chronic Coronary Syndrome Receiving Oral Anticoagulation Common Diseases in Clinical Cohorts — Not Always What They Seem Sotatercept for Pulmonary Arterial Hypertension within the First Year after Diagnosis  Journal of  American Medical AssociationBioresorbable vs Metallic Occluders for Transcatheter Atrial Septal Defect Closure Annals of Internal MedicineTrends in Cancer Incidence in Younger and Older Adults: An International Comparative Analysis  British Medical JournalSodium-glucose cotransporter-2 inhibitors and risk of autoimmune rheumatic diseases JAMA oncology Risk Factors for Valvulopathy Among Childhood Cancer Survivors Gastroenterology Dietary Fiber Modulates the Window of Susceptibility to Clostridioides difficile Infection  Clinical Gastroenterology Prevalence and Pathophysiology of Loose Stools and Their Impact on Clinical Severity and Quality of Life in Women With Fecal Incontinence Clinical Infectious DiseasesPhase 1 Evaluation of VH4524184, a Third-Generation Integrase Strand Transfer Inhibitor With an Enhanced Resistance Profile  Journal of Clinical Rheumatology A Novel Scoring System for Diagnosing Systemic Lupus Erythematosus–Related Cytopenias: Insights From a Cohort Study  CirculationRedefining the Genetic Architecture of Hypertrophic Cardiomyopathy: Role of Intermediate-Effect Variants Journals of the American College of CardiologyTrade-Off Between Bleeding and Ischemic Events From Left Ventricular Assist Devices: A EUROMACS Registry Analysis JAMA CardiologyAge-Stratified Effect of Rivaroxaban Monotherapy for Atrial Fibrillation in Stable Coronary Artery DiseaseA Post Hoc Analysis of the AFIRE Randomized Clinical Trial  Journal of Clinical Endocrinology & MetabolismUsing a Composite Summary of Daily Sex Hormones to Gauge Time Until Menopause: A Focus on Pregnanediol Glucuronide (PDG)  Diabetes careDifferential Effect of GLP-1 Receptor Agonists and SGLT2 Inhibitors on Lower-Extremity Amputation Outcomes in Type 2 Diabetes: A Nationwide Retrospective Cohort Study  NeurologySoccer Heading Exposure–Dependent Microstructural Injury at Depths of Sulci in Adult Amateur Players  ChestEffect of Ventilator Mode on Ventilator-Free Days in Critically Ill Adults Clinical Journal of American Society of NephrologyComparative Effectiveness of Lubiprostone and Stool Softeners on Risk of Kidney Outcomes in Patients with CKDKidney International reportsRandomized Trial of Dapagliflozin in Patients With Nondiabetic Stage 4 CKD