10 30 2023

Hi, This Week in Medicine, we will be discussing

NEJM

 Patisiran Treatment in Patients with Transthyretin Cardiac Amyloidosis

Automated Insulin Delivery in Women with Pregnancy Complicated by Type 1 Diabetes

Phase 3 Trial of Nemolizumab in Patients with Prurigo Nodularis

Convalescent Plasma for Covid-19–Induced ARDS in Mechanically Ventilated Patients

JAMA

 Pharmacy e-Prescription Dispensing Before and After CancelRx Implementation

Defining Usual Oral Temperature Ranges in Outpatients Using an Unsupervised Learning Algorithm

Cardiac Arrest Survival at Emergency Medical Service Agencies in Catchment Areas With Primarily Black and Hispanic Populations

Annals of Internal Medicine

Association Between Vascular 18F-Fluorodeoxyglucose Uptake at Diagnosis and Change in Aortic Dimensions in Giant Cell Arteritis

Lancet

Intermediate endpoints as surrogates for outcomes in cancer immunotherapy: a systematic review and meta-analysis of phase 3 trials

Journal of Clinical Oncology

Allogeneic Hematopoietic Cell Transplantation Improves Outcome in Myelodysplastic Syndrome Across High-Risk Genetic Subgroups: Genetic Analysis of the Blood and Marrow Transplant Clinical Trials Network 1102 Study

Clinical Gastroenterology

Blood Test Increases Colorectal Cancer Screening in Persons Who Declined Colonoscopy and Fecal Immunochemical Test

Hepatology

Tropifexor plus cenicriviroc combination versus monotherapy in nonalcoholic steatohepatitis: Results from the phase 2b TANDEM study

Clinical Infectious Diseases

Sustained Viral Suppression With Dolutegravir Monotherapy Over 192 Weeks in Patients Starting Combination Antiretroviral Therapy During Primary Human Immunodeficiency Virus Infection (EARLY-SIMPLIFIED): A Randomized, Controlled, Multi-site, Noninferiority Trial 

Journal of infectious Diseases

Interference Between Enteric Viruses and Live-Attenuated Rotavirus Vaccine Virus in Journal of Clinical Rheumatology 

Clinical Characteristics and Prognostic Value of Ro52/SSA Antibodies in Idiopathic Inflammatory Myopathies

Arthritis and Rheumatology

Bone Loss in Inflammatory Rheumatic Musculoskeletal Disease Patients Treated With Low-Dose Glucocorticoids and Prevention by Anti-Osteoporosis Medications

Circulation

Blood Pressure and Oxygen Targets on Kidney Injury After Cardiac Arrest

ACC Latest-in-Cardiology 

Performance of the ACC/AHA Pooled Cohort Cardiovascular Risk Equations in Clinical Practice |

Journal of Clinical Endocrinology & Metabolism

Heart Rate Variability and Incident Type 2 Diabetes in General Population

New Findings on Presentation and Outcome of Patients With Adrenocortical Cancer: Results From a National Cohort Study

Neurology:

Randomized Trial Comparing Low- vs High-Dose IV Dexamethasone for Patients With Moderate to Severe Migraine

Chest

The Effect of Inhaled Corticosteroids on Pneumonia Risk in Patients With COPD-Bronchiectasis Overlap

Lifestyle, Genetic Susceptibility, and the Risk of Idiopathic Pulmonary Fibrosis

Cell-Free DNA Fragmentomes in the Diagnostic Evaluation of Patients With Symptoms Suggestive of Lung Cancer

 The American Journal of Respiratory and Critical Care Medicine

Sleep Apnea Physiological Burdens and Cardiovascular Morbidity and Mortality

  Clinical Journal of American Society of Nephrology

Anti-PLA2R Antibody Levels and Clinical Risk Factors for Treatment Nonresponse in Membranous Nephropathy

  Kidney International

Implications of Complete Proteinuria Remission at any Time in Focal Segmental Glomerulosclerosis: Sparsentan DUET Trial