100% of Nothing is Nothing with Raymond Cohen episode artwork

EPISODE · Feb 24, 2026 · 1H 3M

100% of Nothing is Nothing with Raymond Cohen

from The Crux of Medtech · host Crux of Medtech

Raymond Cohen has spent 40+ years in medtech, never at a big company but always building. After taking Axonics from whiteboard to $500M in revenue and a Boston Scientific exit, he's now chairman of multiple high-growth ventures.In this episode, he breaks down what actually makes a company acquirable, why founders need to get over their fear of dilution, and the immigrant work ethic that's driven his entire career.Key Topics:Why Boston Scientific is outpacing every other strategic acquirer right nowThe "go big or go home" fundraising philosophy behind Spyro Medical's $67M Series AWhat "having the goods" actually means and why most founders don't know if they have themRaymond's criteria for joining a board: clinical problem, addressable market, and the right peopleHow LSI is filling the gap JP Morgan left for private medtech companiesRelated Insights:Neuromodulation as a pharmaceutical replacement: the Spyro asthma thesisCuffless ambulatory blood pressure monitoring and the BioBeat opportunityWhy the best people won't work for paper and how to structure equity properlyThe "tone from the top" principle and cutting underperformers earlyCore Challenges:Founders are paralysed by dilution fear, leading to undercapitalisation and slow execution.Raymonds's view: sell 85% on day one if that's what it takes to win.Too many startups pursue incremental innovation or enter crowded markets "the fifth person in a four-man race."Strategic acquirers beyond Boston Scientific have been passive, limiting exit options and slowing capital recycling in the ecosystem.🎧 Tune in now to hear how a 40-year medtech veteran thinks about building, buying, and betting big.

Raymond Cohen has spent 40+ years in medtech, never at a big company but always building. After taking Axonics from whiteboard to $500M in revenue and a Boston Scientific exit, he's now chairman of multiple high-growth ventures.In this episode, he breaks down what actually makes a company acquirable, why founders need to get over their fear of dilution, and the immigrant work ethic that's driven his entire career.Key Topics:Why Boston Scientific is outpacing every other strategic acquirer right nowThe "go big or go home" fundraising philosophy behind Spyro Medical's $67M Series AWhat "having the goods" actually means and why most founders don't know if they have themRaymond's criteria for joining a board: clinical problem, addressable market, and the right peopleHow LSI is filling the gap JP Morgan left for private medtech companiesRelated Insights:Neuromodulation as a pharmaceutical replacement: the Spyro asthma thesisCuffless ambulatory blood pressure monitoring and the BioBeat opportunityWhy the best people won't work for paper and how to structure equity properlyThe "tone from the top" principle and cutting underperformers earlyCore Challenges:Founders are paralysed by dilution fear, leading to undercapitalisation and slow execution.Raymonds's view: sell 85% on day one if that's what it takes to win.Too many startups pursue incremental innovation or enter crowded markets "the fifth person in a four-man race."Strategic acquirers beyond Boston Scientific have been passive, limiting exit options and slowing capital recycling in the ecosystem.🎧 Tune in now to hear how a 40-year medtech veteran thinks about building, buying, and betting big.

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100% of Nothing is Nothing with Raymond Cohen

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This episode is 1 hour and 3 minutes long.

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This episode was published on February 24, 2026.

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Raymond Cohen has spent 40+ years in medtech, never at a big company but always building. After taking Axonics from whiteboard to $500M in revenue and a Boston Scientific exit, he's now chairman of multiple high-growth ventures.In this episode, he...

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