EPISODE · Jun 1, 2026 · 17 MIN
1061-植物Raf激酶复合体调控质膜质子泵机制
from 聊聊Sci
本研究揭示了植物质膜质子泵（PM H+-ATPase）激活的核心分子机制，重点关注其C端Thr881位点的磷酸化过程。研究发现，由C5-Raf和C7-Raf两种Raf类蛋白激酶组成的异源复合体是直接驱动该位点磷酸化的关键。在拟南芥中，Raf36通过此途径调节植物整体生长，而HT1激酶则在保卫细胞中与CBC1/2协作，响应光照和二氧化碳浓度变化以诱导气孔开放。这种激酶调节模块从苔藓类植物到被子植物都具有高度的进化保守性。该发现不仅完善了光诱导气孔运动的信号传导模型，还为通过基因工程手段提升农作物产量提供了新的理论支撑。References:Takase H, Nagano A, Yamauchi S, et al. Raf-like protein kinase heterocomplexes directly regulate the plant plasma membrane H+-ATPase[J]. Science, 2026, 392(6799): 755-760.前往小宇宙评论区与主播互动
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1061-植物Raf激酶复合体调控质膜质子泵机制
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