11 6 2023

Hi, This Week in Medicine, we will be discussing

 New England Journal of Medicine

Sparsentan versus Irbesartan in Focal Segmental Glomerulosclerosis

 A Phase 2 Trial of Sibeprenlimab in Patients with IgA Nephropathy

 Thalidomide for Recurrent Bleeding Due to Small-Intestinal Angiodysplasia

 Pulsed Field or Conventional Thermal Ablation for Paroxysmal Atrial Fibrillation

Perioperative Durvalumab for Resectable Non–Small-Cell Lung Cancer

 Journal of Hypertension

Sedentary behavior and risk of cardiovascular disease and all-cause mortality in United States adults with hypertension

 Hypertension journal

Blood Pressure and Cardiovascular Disease Mortality Among US Adults: A Sex-Stratified Analysis, 1999–2019

 Journal of American Medical Association

Changes in Physician Electronic Health Record Use With the Expansion of Telemedicine

  Management for Opioid Use Disorder Treatment

 Annals of Internal Medicine

Chronotype, Unhealthy Lifestyle, and Diabetes Risk in Middle-Aged U.S. Women

 Suspected Bronchiectasis and Mortality in Adults With a History of Smoking Who Have Normal and Impaired Lung Function

 Journal of Clinical Oncology

Trastuzumab Deruxtecan in Patients With HER2-Mutant Metastatic Non–Small-Cell Lung Cancer: Primary Results From the Randomized, Phase II DESTINY-Lung02 Trial

  Hepatology

Effects of pegozafermin on the liver and on metabolic comorbidities in subjects with biopsy-confirmed nonalcoholic steatohepatitis

  Clinical microbiology and Infection

To evaluate the safety and efficacy of switching from intravenous (IV) to oral antimicrobial therapy in patients with Enterobacterales bacteraemia, after completion of 3–5 days of microbiologically active IV therapy.

 Journal of infectious Diseases

Sociodemographic Variables Can Guide Prioritized Testing Strategies for Epidemic Control in Resource-Limited Contexts

  Arthritis and Rheumatology

Rheumatoid Arthritis–Specific Autoimmunity in the Lung Before and at the Onset of Disease

Clinical and Biomarker Responses to BI 655064, an Antagonistic Anti-CD40 Antibody, in Patients With Active Lupus Nephritis: A Randomized, Double-Blind, Placebo-Controlled, Phase II Trial

 Circulation October 24, 2023 

Oral Anticoagulation Use and Left Atrial Appendage Occlusion in LAAOS III

American College of Cardiology

Lead Extraction and Mortality Among Patients With CIED Infection

China Tongxinluo Study for Myocardial Protection in Patients With Acute Myocardial Infarction

Relationship of Daily Step Counts to All-Cause Mortality and Cardiovascular Events

 Clinical Endocrinology & Metabolism

Thyroid Function Tests in Children and Adolescents With Trisomy 21: Definition of Syndrome-Specific Reference Ranges

  BLOOD ADVANCES

JAK2V617F mutation is highly prevalent in patients with ischemic stroke: a case-control study

 The American Journal of Respiratory and Critical Care Medicine

Improvement in Lung Clearance Index and Chest Computed Tomography Scores with Elexacaftor/Tezacaftor/Ivacaftor Treatment in People with Cystic Fibrosis Aged 12 Years and Older – The RECOVER Trial

Incorporating Effects of Time Accrued on the Waiting List into Lung Transplantation Survival Models

INTENSIVE CARE MEDICINE

Initiation of continuous renal replacement therapy versus intermittent hemodialysis in critically ill patients with severe acute kidney injury: a secondary analysis of STARRT-AKI trial

  JOURNAL OF AMERICAN SOCIETY OF MEDICINE, SURGERY

Primary Care Physician Follow-Up and 30-Day Readmission After Emergency General Surgery Admissions

Urology Journal

Acute Kidney Injury Within 90Days of Radical Cystectomy for Bladder Cancer: Incidence and Risk Factors