11 6 2023

Hi, This Week in Medicine, we will be discussing New England Journal of MedicineSparsentan versus Irbesartan in Focal Segmental Glomerulosclerosis A Phase 2 Trial of Sibeprenlimab in Patients with IgA Nephropathy Thalidomide for Recurrent Bleeding Due to Small-Intestinal Angiodysplasia Pulsed Field or Conventional Thermal Ablation for Paroxysmal Atrial FibrillationPerioperative Durvalumab for Resectable Non–Small-Cell Lung Cancer   Journal of HypertensionSedentary behavior and risk of cardiovascular disease and all-cause mortality in United States adults with hypertension Hypertension journalBlood Pressure and Cardiovascular Disease Mortality Among US Adults: A Sex-Stratified Analysis, 1999–2019 Journal of American Medical AssociationChanges in Physician Electronic Health Record Use With the Expansion of Telemedicine  Management for Opioid Use Disorder Treatment Annals of Internal MedicineChronotype, Unhealthy Lifestyle, and Diabetes Risk in Middle-Aged U.S. Women  Suspected Bronchiectasis and Mortality in Adults With a History of Smoking Who Have Normal and Impaired Lung Function Journal of Clinical OncologyTrastuzumab Deruxtecan in Patients With HER2-Mutant Metastatic Non–Small-Cell Lung Cancer: Primary Results From the Randomized, Phase II DESTINY-Lung02 Trial  HepatologyEffects of pegozafermin on the liver and on metabolic comorbidities in subjects with biopsy-confirmed nonalcoholic steatohepatitis   Clinical microbiology and Infection To evaluate the safety and efficacy of switching from intravenous (IV) to oral antimicrobial therapy in patients with Enterobacterales bacteraemia, after completion of 3–5 days of microbiologically active IV therapy. Journal of infectious DiseasesSociodemographic Variables Can Guide Prioritized Testing Strategies for Epidemic Control in Resource-Limited Contexts  Arthritis and RheumatologyRheumatoid Arthritis–Specific Autoimmunity in the Lung Before and at the Onset of Disease Clinical and Biomarker Responses to BI 655064, an Antagonistic Anti-CD40 Antibody, in Patients With Active Lupus Nephritis: A Randomized, Double-Blind, Placebo-Controlled, Phase II Trial Circulation October 24, 2023 Oral Anticoagulation Use and Left Atrial Appendage Occlusion in LAAOS III American College of CardiologyLead Extraction and Mortality Among Patients With CIED Infection China Tongxinluo Study for Myocardial Protection in Patients With Acute Myocardial Infarction Relationship of Daily Step Counts to All-Cause Mortality and Cardiovascular Events Clinical Endocrinology & MetabolismThyroid Function Tests in Children and Adolescents With Trisomy 21: Definition of Syndrome-Specific Reference Ranges  BLOOD ADVANCESJAK2V617F mutation is highly prevalent in patients with ischemic stroke: a case-control study The American Journal of Respiratory and Critical Care MedicineImprovement in Lung Clearance Index and Chest Computed Tomography Scores with Elexacaftor/Tezacaftor/Ivacaftor Treatment in People with Cystic Fibrosis Aged 12 Years and Older – The RECOVER Trial Incorporating Effects of Time Accrued on the Waiting List into Lung Transplantation Survival Models INTENSIVE CARE MEDICINEInitiation of continuous renal replacement therapy versus intermittent hemodialysis in critically ill patients with severe acute kidney injury: a secondary analysis of STARRT-AKI trial  JOURNAL OF AMERICAN SOCIETY OF MEDICINE, SURGERYPrimary Care Physician Follow-Up and 30-Day Readmission After Emergency General Surgery Admissions  Urology JournalAcute Kidney Injury Within 90Days of Radical Cystectomy for Bladder Cancer: Incidence and Risk Factors