11 7 2024

Hi, This Week in Medicine, we will be discussing

 New England Journal of Medicine

Invasive Treatment Strategy for Older Patients with Myocardial Infarction

Randomized Trial of Very Early Medication Abortion

Neoadjuvant Nivolumab and Ipilimumab in Resectable Stage III Melanoma

Final Results for Adjuvant Dabrafenib plus Trametinib in Stage III Melanoma

  Journal of  American Medical Association

Postmarketing Surveillance of Inferior Vena Cava Filters Among US Medicare Beneficiaries

The SAFE-IVC Study

A Digital Health Behavior Intervention to Prevent Childhood Obesity

The Greenlight Plus Randomized Clinical Trial

  Annals of Internal Medicine

Ensuring Safe Practice by Late Career Physicians: Institutional Policies and Implementation Experiences

 British Medical Journal

SGLT-2 inhibitors and mortality among patients with heart failure with reduced ejection fraction

  Lancet

Optimal timing of anticoagulation after acute ischaemic stroke with atrial fibrillation (OPTIMAS): a multicentre, blinded-endpoint, phase 4, randomised controlled trial

  Cancer Journal for Clinicians

Epidemiology, treatment patterns, and clinical outcomes in de novo oligometastatic hormone-sensitive prostate cancer

 Journal of Clinical Oncology

Addition of Metastasis-Directed Therapy to Systemic Therapy for Oligometastatic Pancreatic Ductal Adenocarcinoma (EXTEND): A Multicenter, Randomized Phase II Trial

  journal of Hepatology

Diagnostic performance of non-invasive tests in patients with MetALD in a health check-up cohort

Histological improvements following energy restriction and exercise: The role of insulin resistance in resolution of MASH

 Gastroenterology

Gluten-Dependent Activation of CD4+ T Cells by MHC Class II–Expressing Epithelium

 Clinical Gastroenterology

 Vonoprazan is Efficacious for Treatment of Heartburn in Non-erosive Reflux Disease: A Randomized Trial

 Clinical Infectious Diseases

Successful Treatment of Carbapenem-Resistant Acinetobacter baumannii Meningitis With Sulbactam-Durlobactam

 Rheumatology 

Comprehensive Enteroviral Serology Links Infection and Anti‐Melanoma Differentiation‐Associated Protein 5 Dermatomyositis

 Journal of Clinical Rheumatology 

 Factors Associated With Successful Withdrawal of Biologic Agents in Children With Colchicine-Resistant Familial Mediterranean Fever

   Circulation

Contemporary Outcomes and Trends for the Transseptal Mitral Valve-in-Valve Procedure Using Balloon Expandable Transcatheter Valves in the United States

  Journals of the American College of Cardiology

Reaffirmation of Mechanistic Proteomic Signatures Accompanying SGLT2 Inhibition in Patients With Heart Failure: A Validation Cohort of the EMPEROR Program

Leadless Ultrasound-Based Cardiac Resynchronization System in Heart Failure

  Journal of Clinical Endocrinology & Metabolism

Increased Prevalence of Germline Pathogenic CHEK2 Variants in Individuals With Pituitary Adenomas 

 Diabetes care

Health Care Utilization and Costs Associated With Empagliflozin in Older Adults With Type 2 Diabetes

 Neurology

Frequency and Longitudinal Course of Behavioral and Neuropsychiatric Symptoms in Participants With Genetic Frontotemporal Dementia

  Chest

Primary Ciliary Dyskinesia in Adult Bronchiectasis

  American Journal of Respiratory and Critical Care Medicine

Discovery and Validation of a Volatile Signature of Eosinophilic Airway Inflammation in Asthma

 Clinical Journal of American Society of Nephrology

Urine Output and Acute Kidney Injury in Neonates/Younger Children: A Prospective Study of Cardiac Surgery Patients with Indwelling Urinary Catheters

Large Discordance between Creatinine-Based and Cystatin C–Based eGFRs is Associated with Falls, Hospitalizations, and Death in Older Adults

  Kidney International reports

Systematic Review of Individual Patient Data COVID-19 Infection and Vaccination–Associated Thrombotic Microangiopathy