11 7 2024

Hi, This Week in Medicine, we will be discussing  New England Journal of MedicineInvasive Treatment Strategy for Older Patients with Myocardial Infarction Randomized Trial of Very Early Medication AbortionNeoadjuvant Nivolumab and Ipilimumab in Resectable Stage III MelanomaFinal Results for Adjuvant Dabrafenib plus Trametinib in Stage III Melanoma  Journal of  American Medical AssociationPostmarketing Surveillance of Inferior Vena Cava Filters Among US Medicare BeneficiariesThe SAFE-IVC Study A Digital Health Behavior Intervention to Prevent Childhood ObesityThe Greenlight Plus Randomized Clinical Trial  Annals of Internal MedicineEnsuring Safe Practice by Late Career Physicians: Institutional Policies and Implementation Experiences British Medical JournalSGLT-2 inhibitors and mortality among patients with heart failure with reduced ejection fraction  LancetOptimal timing of anticoagulation after acute ischaemic stroke with atrial fibrillation (OPTIMAS): a multicentre, blinded-endpoint, phase 4, randomised controlled trial  Cancer Journal for CliniciansEpidemiology, treatment patterns, and clinical outcomes in de novo oligometastatic hormone-sensitive prostate cancer Journal of Clinical OncologyAddition of Metastasis-Directed Therapy to Systemic Therapy for Oligometastatic Pancreatic Ductal Adenocarcinoma (EXTEND): A Multicenter, Randomized Phase II Trial  journal of HepatologyDiagnostic performance of non-invasive tests in patients with MetALD in a health check-up cohort Histological improvements following energy restriction and exercise: The role of insulin resistance in resolution of MASH Gastroenterology Gluten-Dependent Activation of CD4+ T Cells by MHC Class II–Expressing Epithelium Clinical Gastroenterology  Vonoprazan is Efficacious for Treatment of Heartburn in Non-erosive Reflux Disease: A Randomized Trial Clinical Infectious DiseasesSuccessful Treatment of Carbapenem-Resistant Acinetobacter baumannii Meningitis With Sulbactam-Durlobactam Rheumatology Comprehensive Enteroviral Serology Links Infection and Anti‐Melanoma Differentiation‐Associated Protein 5 Dermatomyositis Journal of Clinical Rheumatology  Factors Associated With Successful Withdrawal of Biologic Agents in Children With Colchicine-Resistant Familial Mediterranean Fever   CirculationContemporary Outcomes and Trends for the Transseptal Mitral Valve-in-Valve Procedure Using Balloon Expandable Transcatheter Valves in the United States  Journals of the American College of CardiologyReaffirmation of Mechanistic Proteomic Signatures Accompanying SGLT2 Inhibition in Patients With Heart Failure: A Validation Cohort of the EMPEROR Program Leadless Ultrasound-Based Cardiac Resynchronization System in Heart Failure  Journal of Clinical Endocrinology & MetabolismIncreased Prevalence of Germline Pathogenic CHEK2 Variants in Individuals With Pituitary Adenomas  Diabetes careHealth Care Utilization and Costs Associated With Empagliflozin in Older Adults With Type 2 Diabetes NeurologyFrequency and Longitudinal Course of Behavioral and Neuropsychiatric Symptoms in Participants With Genetic Frontotemporal Dementia  ChestPrimary Ciliary Dyskinesia in Adult Bronchiectasis  American Journal of Respiratory and Critical Care MedicineDiscovery and Validation of a Volatile Signature of Eosinophilic Airway Inflammation in Asthma Clinical Journal of American Society of NephrologyUrine Output and Acute Kidney Injury in Neonates/Younger Children: A Prospective Study of Cardiac Surgery Patients with Indwelling Urinary Catheters Large Discordance between Creatinine-Based and Cystatin C–Based eGFRs is Associated with Falls, Hospitalizations, and Death in Older Adults  Kidney International reportsSystematic Review of Individual Patient Data COVID-19 Infection and Vaccination–Associated Thrombotic Microangiopathy