EPISODE · Jun 13, 2026 · 17 MIN
1124-周细胞：组织形态发生的器官特异性调节因子
from 聊聊Sci
这项研究利用小鼠遗传学和单细胞转录组测序技术，揭示了周细胞（Pericytes）作为器官特异性信号中心在组织发育中的关键作用。研究发现，周细胞分泌的旁路信号分子具有明显的器官差异性：在肺部，周细胞产生的HGF和BDNF通过与上皮细胞和内皮细胞互动，驱动肺泡化及血管生成。而在脑部，这些因子并不重要，取而代之的是由周细胞分泌的Nodal蛋白，它直接调控脑血管的生长、屏障功能以及星形胶质细胞与小胶质细胞的稳态。实验证明，缺失这些特定因子会导致肺发育受阻或诱发脑部炎症反应及血管渗漏。总之，该研究确立了周细胞在不同生理环境下调控器官形态发生的特异性功能机制。References:Rasouli, S.J., Kruse, K., Diéguez-Hurtado, R. et al. Pericytes are organ-specific regulators of tissue morphogenesis. Nat Commun 17, 4229 (2026). https://doi.org/10.1038/s41467-026-71643-1前往小宇宙评论区与主播互动
Embed this episode
Ready to play
1124-周细胞：组织形态发生的器官特异性调节因子
0:00
17:22
1×
No transcript for this episode yet
Similar Episodes
No similar episodes found.
Similar Podcasts
Forfeiture Book Review: Ecocide and Sci-Fi
JP et al.
A whizz bang review of the complex themes in the new ecological Sci-Fi novel, FORFEITURE by JP Nebra
Deep Dream State
Neural Nets And Pretty Patterns
Deep Dream State is a full-cast dystopian sci-fi and desire horror audio drama by Neural Nets and Pretty Patterns. As the originating work of desire horror, it locates the uncanny inside wanting itself. While conventional horror positions you against a threat, desire horror implicates you in it. The horror emerges from recognition: the realization of why characters stay, and why surrender feels like relief. Since 2017, the show has used research in dream science, surveillance studies, behavioral economics, and advertising technology to examine systems of control through immersive sound design and full-cast performance.
Frequently Asked Questions
How long is this episode of 聊聊Sci?
This episode is 17 minutes long.
When was this 聊聊Sci episode published?
This episode was published on June 13, 2026.
Can I download this 聊聊Sci episode?
Yes. Use the download control on the episode player to save the publisher-provided media file.
URL copied to clipboard!