119. HPA-Axis Dysfunction & The Adrenal Gland Peptide Bioregulator, Glandokort (+ A Deep Dive into How Bioregulators Work)

In this episode, we delve into the science behind peptide bioregulators, specifically focusing on Glandokort, a natural extract from the adrenal gland. We explore the unique characteristics and mechanisms of peptide bioregulators, highlighting their tissue-specific effects and role in gene regulation. Additionally, we provide an overview of the adrenal glands' anatomy and functions, and discuss how Glandokort may aid in normalizing adrenal gland protein synthesis in the context of some types of adrenal insufficiency. Understanding Peptides Definition of peptides: Short chains of amino acids Comparison of peptide bioregulators and other peptides (e.g., BPC-157) Size and function of peptide bioregulators Bioregulators penetrate the cell membrane AND the nuclear membrane Function of Peptide Bioregulators Role in restoring organ balance Tissue-specific effect Gene Regulation and Cellular Differentiation Importance of gene regulation Nuance of cell differentiation and gene expression Today's focus: gene regulation impacting a cell's functional activity Mechanism of Bioregulators Interaction with DNA and gene expression Binding to histone proteins Promotion of gene expression in tissue-specific cells History and Development of Peptide Bioregulators Early isolation from animal tissues Examples of tissues used for extraction Development of the synthetic peptide bioregulators Natural vs. Synthetic Peptide Bioregulators Availability of natural and synthetic supplements Focusing on the natural extract of the adrenal gland: Glandokort Adrenal Glands Overview Location and function of adrenal glands Division into cortex and medulla 7.1 Adrenal Cortex Zona Glomerulosa: Production of mineralocorticoids (aldosterone) Zona Fasciculata: Production of glucocorticoids (cortisol) Zona Reticularis: Production of androgens 7.2 Adrenal Medulla Production of catecholamines (adrenaline and noradrenaline) Role in 'fight or flight' response Glandokort Supplement Description: Natural adrenal gland peptides Function: Normalizing adrenal gland protein synthesis Context of HPA-axis dysfunction or "adrenal fatigue" Importance of working with a licensed medical professional More research is needed Thanks for tuning in! Get Chloe's Book Today! "⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠75 Gut-Healing Strategies & Biohacks⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠" If you liked this episode, please leave a rating and review or share it to your stories over on Instagram. If you tag @synthesisofwellness, Chloe would love to personally thank you for listening! Follow Chloe on Instagram ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@synthesisofwellness⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Follow Chloe on TikTok @chloe_c_porter Visit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠synthesisofwellness.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ to purchase products, subscribe to our mailing list, and more! Or visit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠linktr.ee/synthesisofwellness⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ to see all of Chloe's links, schedule a BioPhotonic Scanner consult with Chloe, or support the show! Thanks again for tuning in!