12 16 2024

Hi, This Week in Medicine, we will be discussing

 New England Journal of Medicine

PCI in Patients Undergoing Transcatheter Aortic-Valve Implantation

Insulin Efsitora versus Degludec in Type 2 Diabetes without Previous Insulin Treatment

Bedaquiline Monotherapy for Multibacillary Leprosy

Obecabtagene Autoleucel in Adults with B-Cell Acute Lymphoblastic Leukemia

 CRISPR-Cas9 Gene Editing with Nexiguran Ziclumeran for ATTR Cardiomyopathy

Journal of  American Medical Association

Electronic Sepsis Screening Among Patients Admitted to Hospital Wards

Early Restrictive vs Liberal Oxygen for Trauma Patients: The TRAUMOX2 Randomized Clinical Trial

 Annals of Internal Medicine

Development and Evaluation of a Comprehensive Prediction Model for Incident Coronary Heart Disease Using Genetic, Social, and Lifestyle–Psychological Factors: A Prospective Analysis of the UK Biobank

British Medical Journal

Contemporary menopausal hormone therapy and risk of cardiovascular disease: Swedish nationwide register based emulated target trial

Lancet

National-level and state-level prevalence of overweight and obesity among children, adolescents, and adults in the USA, 1990–2021, and forecasts up to 2050

Journal of Clinical Oncology

Clinical Outcomes and Histologic Findings of Patients With Hepatocellular Carcinoma With Durable Partial Response or Durable Stable Disease After Receiving Atezolizumab Plus Bevacizumab

Hepatology

Low-to-moderate alcohol consumption is associated with increased fibrosis in individuals with metabolic dysfunction-associated steatotic liver disease

 Gastroenterology

 Exon-Skipping–Based Subtyping of Colorectal Cancers

Rheumatology 

Revisiting the Link Between HLA-DRB1 Alleles and Autoantibodies in Rheumatoid Arthritis: Association of non-Shared Epitope Alleles *09 and *15 With High Levels of Anti–Citrullinated Peptide/Protein Antibodies

 Journal of Clinical Rheumatology 

Periprosthetic Joint Infection in Patients With Inflammatory Arthritis: Optimal Tests to Differentiate From Flares

 Circulation

Randomized Invitation to Systematic NT-proBNP and ECG Screening in 75-Year-Olds to Detect Atrial Fibrillation: STROKESTOP II

  Journals of the American College of Cardiology

Hospitalization of Symptomatic Patients With Heart Failure and Moderate to Severe Functional Mitral Regurgitation Treated With MitraClip: Insights From RESHAPE-HF2

Endocrinology

 Diabetes care

Initiation of Intermittently Scanned Continuous Glucose Monitoring Is Associated With Reduced Hospitalization for Acute Diabetes Events and Cardiovascular Complications in Adults With Type 1 Diabetes

Chest

Impact of Dyspnea on Adults With Respiratory Symptoms Without a Defined Diagnosis

Comparison of Early and Late Norepinephrine Administration in Patients With Septic Shock

The American Journal of Respiratory and Critical Care Medicine

Application of the European Respiratory Society/American Thoracic Society Spirometry Standards and Race-Neutral Equations in the COPDGene Study

Next we will be discussing articles In the field of Nephrology

Clinical Journal of American Society of Nephrology

Bioimpedance-Guided Fluid Removal in Continuous KRT: The VENUS Randomized Clinical Trial

Kidney International reports

Anti Phospholipase A2 Receptor 1 Antibodies and Membranous Nephropathy Recurrence After Kidney Transplantation

Combination Therapy With Rituximab and Low-Dose Cyclophosphamide and Prednisone in Membranous Nephropathy