12 18 2023

Hi, This Week in Medicine, we will be discussing New England Journal of MedicineSemaglutide and Cardiovascular Outcomes in Obesity without Diabetes Efficacy and Safety of an mRNA-Based RSV PreF Vaccine in Older Adults Recombinant or Standard-Dose Influenza Vaccine in Adults under 65 Years of Age Three-Year Overall Survival with Tebentafusp in Metastatic Uveal Melanoma  Annals of Internal MedicineDevelopment and Validation of the CANHEART Population-Based Laboratory Prediction Models for Atherosclerotic Cardiovascular Disease Nature MedicineInhibition of the KCa2 potassium channel in atrial fibrillation: a randomized phase 2 trial  LancetPembrolizumab plus chemotherapy versus chemotherapy in untreated advanced pleural mesothelioma in Canada, Italy, and France: a phase 3, open-label, randomised controlled trial  Journal of Clinical OncologyHigh-Dose Methotrexate as CNS Prophylaxis in High-Risk Aggressive B-Cell Lymphoma  journal of HepatologyBifidobacterium pseudolongum-generated acetate suppresses non-alcoholic fatty liver disease-associated hepatocellular carcinoma Incidence and outcomes of acute kidney injury including hepatorenal syndrome in hospitalized patients with cirrhosis in the US Clinical GastroenterologyReflux Symptoms Increase Following Sleeve Gastrectomy Despite Triage of Symptomatic Patients to Roux-en-Y Gastric Bypass Safety and Efficacy of Endoscopic Full Thickness Resection of Upper Gastrointestinal Lesions Using a Full Thickness Resection Device: A Systematic Review and Meta-analysis  Clinical Infectious DiseasesPatient Characteristics, Microbiology, and Mortality of Infective Endocarditis After Transcatheter Aortic Valve Implantation Temporal Trends in Hepatitis C–Related Hospitalizations, United States, 2000–2019  Journal of Clinical Rheumatology Unintentional Monotherapy in Rheumatoid Arthritis Patients Receiving Tofacitinib and Drug Survival Rate of Tofacitinib Arthritis and RheumatologyA Randomized, Double-Blind, Sham-Controlled, Clinical Trial of Auricular Vagus Nerve Stimulation for the Treatment of Active Rheumatoid Arthritis  CirculationRivaroxaban Plus Aspirin Versus Aspirin Alone After Endovascular Revascularization for Symptomatic PAD: Insights From VOYAGER PAD American College of Cardiology Predictors of Outcomes in Mild Pulmonary Hypertension  Safety and Tolerability of Inclisiran for Treatment of Hypercholesterolemia in 7 Clinical Trials Journal of Clinical Endocrinology & MetabolismDI/cle, a Measure Consisting of Insulin Sensitivity, Secretion, and Clearance, Captures Diabetic States Tissue Glucocorticoid Metabolism in Adrenal Insufficiency: A Prospective Study of Dual-release Hydrocortisone Therapy Neurology:Association of Neighborhood-Level Socioeconomic Factors With Delay to Hospital Arrival in Patients With Acute Stroke ChestCT Scan Differences of Pulmonary TB According to Presence of Pleural Effusion  The American Journal of Respiratory and Critical Care MedicineImpact of Undiagnosed Chronic Obstructive Pulmonary Disease and Asthma on Symptoms, Quality of Life, Healthcare Use, and Work Productivity  Clinical Gastroenterology AND HepatologyLong-term Risks of Recurrence After Hospital Discharge for Acute Lower Gastrointestinal Bleeding: A Large Nationwide Cohort Study  Clinical Journal of American Society of Nephrology.Cystatin C–Based eGFR Changes during Gender-Affirming Hormone Therapy in Transgender Individuals   Kidney International reportsSex/Gender-Based Disparities in Early Transplant Access by Attributed Cause of Kidney Disease–Evidence from a Multiregional Cohort in the Southeast United States