12 2 2024

Hi, This Week in Medicine, we will be discussing New England Journal of MedicineOverall Survival with Pembrolizumab in Early-Stage Triple-Negative Breast Cancer Fractional Doses of Pneumococcal Conjugate Vaccine — A Noninferiority Trial Nivolumab plus Ipilimumab in Microsatellite-Instability–High Metastatic Colorectal Cancer Journal of  American Medical AssociationAssociation of Severe Maternal Morbidity With Subsequent Birth Intravenous Lidocaine for Gut Function Recovery in Colonic Surgery Transcatheter Edge-to-Edge Repair for Severe Isolated Tricuspid RegurgitationThe Tri.Fr Randomized Clinical Trial  Annals of Internal MedicineAssociation of Work Control With Burnout and Career Intentions Among U.S. Physicians: A Multi-Institution Stud   British Medical JournalContemporary menopausal hormone therapy and risk of cardiovascular disease LancetBalloon guide catheters for endovascular thrombectomy in patients with acute ischaemic stroke due to large-vessel occlusion in China (PROTECT-MT): a multicentre, open-label, blinded-endpoint, randomised controlled trial  Cancer Journal for CliniciansA phase 2 study of a brachyury-targeting vaccine in combination with radiation therapy for the treatment of advanced chordoma Journal of Clinical OncologyProspective Study of Supplemental Screening With Contrast-Enhanced Mammography in Women With Elevated Risk of Breast Cancer: Results of the Prevalence Round journal of HepatologyEfficacy, tolerability and pharmacokinetics of survodutide, a glucagon/glucagon-like peptide-1 receptor dual agonist, in cirrhosis Glutaryl-CoA dehydrogenase suppresses tumor progression and shapes an anti-tumor microenvironment in hepatocellular carcinoma Gastroenterology Gut Pathobiont–Derived Outer Membrane Vesicles Drive Liver Inflammation and Fibrosis in Primary Sclerosing Cholangitis–Associated Inflammatory Bowel Disease Clinical Gastroenterology  Updated Reference Intervals for Alanine Aminotransferase in a Metabolically and Histologically Normal Population   Clinical Infectious DiseasesThe Use of Long-term Antibiotics for Suppression of Bacterial Infections  Rheumatology Implementing Patient Health Questionnaire Depression Screening in Inflammatory Arthritis Clinic   Journal of Clinical Rheumatology   CirculationErbB3 Governs Endothelial Dysfunction in Hypoxia-Induced Pulmonary Hypertension  Journals of the American College of CardiologyRecaticimab Monotherapy for Nonfamilial Hypercholesterolemia and Mixed Hyperlipemia: The Phase 3 REMAIN-1 Randomized Trial  JAMA CardiologyRoutine Protamine Administration for Bleeding in Transcatheter Aortic Valve ImplantationThe ACE-PROTAVI Randomized Clinical Trial Journal of Clinical Endocrinology & MetabolismObesity, Inflammation, and Clinical Outcomes in COVID-19: A Multicenter Prospective Cohort Study  Diabetes careCholine Metabolites and 15-Year Risk of Incident Diabetes in a Prospective Cohort of Adults: Coronary Artery Risk Development in Young Adults (CARDIA) Study   NeurologySGLT2 Inhibitor Use and Risk of Dementia and Parkinson Disease Among Patients With Type 2 Diabetes ChestRethinking Blood Eosinophils for Assessing Inhaled Corticosteroids Response in COPD   The American Journal of Respiratory and Critical Care MedicinePreacinar Arterial Dilation Mediates Outcomes of Quantitative Interstitial Abnormalities in the COPDGene Study Clinical Journal of American Society of NephrologyAcute Myocardial Infarction and Chronic Kidney Disease: A Nationwide Cohort Study on Management and Outcomes from 2010 to 2022 Kidney International reportsRandomized Trial of Patiromer on Efficacy to Reduce Episodic Hyperkalemia in Patients with ESKD Treated With Hemodialysis