128: The Truth About GLP-1 Drugs and Who Should (and Shouldn’t) Take Them with Dr. Susan Brian

In this episode of Keeping Abreast, Dr. Jenn Simmons is joined by Dr. Susan Brian, an Ivy League–trained endocrinologist, certified menopause specialist, and researcher, to discuss how GLP-1 medications are transforming the treatment of metabolic dysfunction.They explore how therapies like semaglutide and tirzepatide work beyond weight loss, why metabolic disease often goes undiagnosed for years, and how GLP-1s impact diabetes, fatty liver disease, cardiovascular risk, and body composition. The conversation addresses appropriate versus inappropriate use, real risks versus media-driven fear, and why resistance training is essential to protect muscle during weight loss.Dr. Brian also discusses emerging questions around GLP-1s in cancer outcomes and longevity, emphasizing the importance of individualized prescribing, proper screening, and patient education.In This Episode, You’ll LearnWhy GLP-1 medications have fundamentally changed metabolic medicineHow GLP-1s compare to older treatments like metforminWho is an appropriate candidate for GLP-1 therapyHow GLP-1–related weight loss may impact breast cancerWhy early screening for metabolic dysfunction mattersHow to preserve muscle while losing weightWhen microdosing or maintenance dosing may make senseHow to avoid common side effects linked to rapid weight lossEpisode Timeline:00:00 Introduction to GLP-1 and Metabolic Health06:32 Appropriate vs. Inappropriate Use of GLP-112:29 Understanding Metabolic Dysfunction18:18 Menopause and Metabolic Health31:42 Understanding Cardiovascular Protection and Hormonal Treatments38:13 The Role of Newer Drugs in Weight Loss and Fatty Liver48:50 The Importance of Appetite Regulation in Weight Management53:26 Microdosing GLP-1s for Longevity: A New Frontier01:00:19 Safe dosing, rate of weight loss, and best practicesTo talk to a member of Dr. Jenn's team and learn more about working privately with Dr. Jenn visit: https://calendly.com/stephanie-1031/clarity-callTo get your copy of Dr. Jenn's book, The Smart Woman's Guide to Breast Cancer, visit: https://tinyurl.com/SmartWomansBreastCancerGuideTo purchase the auria breast cancer screening test go here https://auria.care/ and use the code DRJENN20 for 20% Off.Connect with Dr. Jenn:Website: https://www.jennsimmonsmd.com/Facebook: https://www.facebook.com/DrJennSimmonsInstagram: https://www.instagram.com/drjennsimmons/YouTube: https://www.youtube.com/@dr.jennsimmons