#132 - Rapamycin, Metformin, Senolytics & Exercise: How to Add DECADES to Your Life episode artwork

EPISODE · May 27, 2025 · 53 MIN

#132 - Rapamycin, Metformin, Senolytics & Exercise: How to Add DECADES to Your Life

from The Dr. Joy Kong Podcast · host Dr. Joy Kong

Everyone wants to live longer and feel better, but the flood of information on supplements, drugs, and fitness can feel overwhelming.I invited Siim Land, an expert and 8-time bestselling author on longevity, to cut through the noise and share simple, evidence-based strategies that really move the needle when it comes to health and lifespan.Siim shares incredible, science-based tips on how we can enhance our healthspan and lifespan without getting lost in the hype.We dig into why exercise, especially combining strength training with cardio, is the single most powerful anti-aging tool. Siim explains how even small changes in daily activity can dramatically reduce your risk of chronic disease and help you live longer.We also talk about what everyone is curious about - Rapamycin, Metformin, Senolytics, and more - and I’m excited to share what the research really says about these popular longevity compounds. Siim also shares why having strong social relationships may be even more important than any pill.If you want clear, practical guidance on living healthier and longer, this episode is for you. Click play and join us for a deep dive into real, sustainable longevity strategies!Key Takeaways:Introduction (00:00)Siim Land's background and journey to longevity (00:30)Exercise is the top anti-aging intervention (05:31)Benefits of moderate daily activity (08:38)Importance of resistance training for muscle and metabolism (10:42)Cardiorespiratory fitness explained with heart rate zones (15:24)Thoughts on supplement overload and key supplements (26:19)Concerns about fish oil oxidation (29:06)Sunscreen vs antioxidants debate (35:53)Senolytics and longevity drugs overview (39:05)Metformin benefits (43:15)Calorie restriction and body composition for longevity (47:11)Social relationships are key to life satisfaction (50:18)Additional Resources: ✨ Connect with Siim LandBooks: https://www.amazon.com/stores/Siim-Land/author/B019H1Z14M?Instagram: https://www.instagram.com/siimland/?hl=enFacebook: https://www.facebook.com/thesiimlandYouTube: https://www.youtube.com/c/siimland—✨ Learn more about how to live a long and pain-free life: https://joykongmd.com/ ✨ Follow me on Facebook: https://www.facebook.com/stemcelldrjoy/ ✨ Follow me on Instagram: https://www.instagram.com/dr_joy_kong/ —Dr. Joy Kong is a regenerative medicine and anti-aging expert. Her podcast is part of her mission to reduce suffering and elevate happiness. Join us every week for the latest holistic health insights that will help you live a long and pain-free life.

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#132 - Rapamycin, Metformin, Senolytics & Exercise: How to Add DECADES to Your Life

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This episode was published on May 27, 2025.

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Everyone wants to live longer and feel better, but the flood of information on supplements, drugs, and fitness can feel overwhelming.I invited Siim Land, an expert and 8-time bestselling author on longevity, to cut through the noise and share...

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