EPISODE · Aug 1, 2026 · 18 MIN
1370-珊瑚共利共生演化中的溶酶体机制作用
from 聊聊Sci
这篇文章探讨了珊瑚与海葵如何通过改造自身的溶酶体系统，演化出维持其生存的共生体细胞器。研究人员利用蛋白质组学技术发现，宿主细胞并非简单地阻止溶酶体降解藻类，而是共同选择了溶酶体蛋白来构建复杂的代谢通道。其中，他们鉴定出一种关键的转运蛋白 SLC26A11，它负责为细胞内的藻类提供光合作用所需的无机碳和硫酸盐。通过 CRISPR/Cas9 基因编辑技术，实验证明缺失该蛋白会导致共生关系破裂，使藻类密度显著下降。这一发现揭示了不同生物体在演化光合共生关系时，存在一条利用现有溶酶体机制的通用路径。该研究不仅深化了对珊瑚礁生态系统分子基础的理解，也为解析细胞内复杂细胞器的起源提供了新视角。References:Maruyama S, Henderson C F, Swinhoe N, et al. Co-option of lysosomal machinery shapes the evolution of the intracellular photosymbiosis supporting coral reefs[J]. Cell, 2026.前往小宇宙评论区与主播互动
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1370-珊瑚共利共生演化中的溶酶体机制作用
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