140: How to Support Your Immune System With a Mushroom Compound Backed by 100+ Studies

Most of the mushroom supplements you'll find on Amazon are ground-up fruiting bodies or myceliated grain in a capsule. AHCC is something entirely different. It's a patented fermented extract from shiitake mycelia that has been used in over 1,000 cancer clinics worldwide, backed by more than 100 published studies, and studied specifically for its effects on natural killer cells, HPV clearance, autoimmune conditions, and liver disease. I'd never heard of it until Mimi Lindquist introduced me to it. Lindquist is the co-founder of The Medicine alongside her husband, Chase. She started as a clinical dental hygienist in Seattle, where she observed firsthand how oral health mirrors systemic health, and eventually followed a thread from a patient's HPV recovery all the way to a research compound developed at the University of Tokyo in 1986. In this episode, Lindquist explains what AHCC actually is, how its manufacturing process makes it fundamentally different from any other mushroom product on the market, and why the clinical research behind it is unusually robust for a supplement. The mechanism that makes AHCC interesting is that it doesn't just boost the immune system indiscriminately. It modulates it. For healthy individuals with normal NK cell counts, it doesn't artificially raise them. For people dealing with HPV, cancerous tumors, or autoimmune conditions where the immune system needs more information, it does. This adaptogenic quality is why AHCC can support both an overactive immune response (as in autoimmune) and an underactive one (as in immune suppression from chronic illness or aging) without contradicting itself. I pushed back on this in the conversation because AHCC is a processed product that requires industrial manufacturing to produce, which doesn't fit neatly into an ancestral framework. Lindquist's response was honest: if we were living 100 years ago without microplastics, glyphosate in the rain, and the chronic stress loads of modern life, we probably wouldn't need it. But that's not the world we live in, and the thousands of testimonials she's received from people who had tried everything else and found relief with AHCC are hard to dismiss. Dosing is two capsules daily for general immune support, four for conditions like HPV, Lyme, or autoimmune, and six to eight for serious situations like tumors or advanced liver disease. Their product, Immune Intel AHCC, uses 750 milligrams per capsule with nothing else added. About Mimi Lindquist:  Meagan (Mimi) Lindquist is the co-founder of The Medicin, alongside her husband Chase. With her background as a clinical dental hygienist, culinary nutrition guide, and AHCC educator, she has been helping others prevent disease for over 12 years. Now, Mimi has dedicated herself entirely to sharing the benefits of Immune Intel AHCC, a mushroom supplement unlike any other, to as many people as possible. Instagram: https://www.instagram.com/mimi_themedicin/ Website: https://www.themedicin.com Podcast: https://feeds.captivate.fm/themedicin/ [Discount Code] Use code PRIMALSHIFT for 10% off Mimi's products → https://www.themedicin.com Thank you to this episode's sponsor, Peluva! Peluva makes minimalist shoes to support optimal foot, back and joint health. I started wearing Peluvas several months ago, and I haven't worn regular shoes since. I encourage you to consider trading your sneakers or training shoes for a pair of Peluvas, and then watch the health of your feet and lower back improve while reducing your risk of injury.  To learn more about why I love Peluva barefoot shoes, check out my in-depth review: https://michaelkummer.com/health/peluva-review/  And use code MICHAEL to get 10% off your first pair: https://michaelkummer.com/go/peluva  In this episode: 00:00 Intro  04:24 From dental health to holistic  07:47 Oral microbiome and inflammation  11:58 How AHCC entered her life  16:58 What AHCC actually is  19:17 Origins and NK cell research  28:13 Immune modulation explained  30:40 Fungal network intelligence  32:30 Primal vs processed supplements  36:15 Modern stress and immune support  40:10 Dosing for different needs  41:19 Kids and pets success stories  43:13 Industrial consistency vs foraging  47:37 How long until results  56:10 Final thoughts Find me on social media for more health and wellness content: Website: https://michaelkummer.com/ YouTube: https://www.youtube.com/@MichaelKummer Instagram: https://www.instagram.com/primalshiftpodcast/ Pinterest: https://www.pinterest.com/michaelkummer/ Twitter/X: https://twitter.com/mkummer82 Facebook: https://www.facebook.com/realmichaelkummer/ [Medical Disclaimer] The information shared on this video is for educational purposes only, is not a substitute for the advice of medical doctors or registered dietitians (which I am not) and should not be used to prevent, diagnose, or treat any condition. Consult with a physician before starting a fitness regimen, adding supplements to your diet, or making other changes that may affect your medications, treatment plan, or overall health. [Affiliate Disclaimer] I earn affiliate commissions from some of the brands and products I review on this channel. While that doesn't change my editorial integrity, it helps make this channel happen. If you'd like to support me, please use my affiliate links or discount code.