EPISODE · Aug 8, 2026 · 25 MIN
1405-Atp8a2调控神经元磷脂酰丝氨酸外露与退行性病变研究
from 聊聊Sci
这份研究揭示了 Atp8a2 蛋白在维持成熟神经元结构完整性与存活中的核心作用。研究发现，在兴奋性中毒及多种神经退行性疾病模型中，Atp8a2 的表达显著下降，导致磷脂酰丝氨酸（PS）在树突分支点等关键结构区域异常暴露。实验表明，Atp8a2 并非仅通过其磷脂翻转酶活性调节膜对称性，其表达水平本身对于稳定神经元骨架至关重要。增加 Atp8a2 的表达能有效抵御神经损伤，为治疗神经退行性疾病提供了新的神经保护靶点。References:Schneider A, Merkel A B, Perta N, et al. Loss of Atp8a2 drives neurodegeneration through the dysregulation of spatiotemporal phosphatidylserine externalization in mature neurons[J]. Cell Death & Disease, 2026, 17(1): 652.前往小宇宙评论区与主播互动
Embed this episode
Ready to play
1405-Atp8a2调控神经元磷脂酰丝氨酸外露与退行性病变研究
0:00
25:31
1×
No transcript for this episode yet
Similar Episodes
No similar episodes found.
Similar Podcasts
Forfeiture Book Review: Ecocide and Sci-Fi
JP et al.
A whizz bang review of the complex themes in the new ecological Sci-Fi novel, FORFEITURE by JP Nebra
Deep Dream State
Neural Nets And Pretty Patterns
Deep Dream State is a full-cast dystopian sci-fi and desire horror audio drama by Neural Nets and Pretty Patterns. As the originating work of desire horror, it locates the uncanny inside wanting itself. While conventional horror positions you against a threat, desire horror implicates you in it. The horror emerges from recognition: the realization of why characters stay, and why surrender feels like relief. Since 2017, the show has used research in dream science, surveillance studies, behavioral economics, and advertising technology to examine systems of control through immersive sound design and full-cast performance.
Frequently Asked Questions
How long is this episode of 聊聊Sci?
This episode is 25 minutes long.
When was this 聊聊Sci episode published?
This episode was published on August 8, 2026.
Can I download this 聊聊Sci episode?
Yes. Use the download control on the episode player to save the publisher-provided media file.
URL copied to clipboard!