141: The Hormone They Told You to Fear Is the One That Could Change Your Life with Karen Martel episode artwork

EPISODE · Apr 24, 2026 · 1H 17M

141: The Hormone They Told You to Fear Is the One That Could Change Your Life with Karen Martel

from Keeping Abreast with Dr. Jenn

In this episode of Keeping Abreast, Dr. Jenn Simmons sits down with hormone specialist Karen Martel to talk about what's really driving the metabolic chaos of perimenopause and menopause and why the solution most women need is the one they've been told to fear. They also tackle one of the most misunderstood topics in women's health: the relationship between estrogen, metabolic health, and breast cancer.What happens when a nutrition expert who helps women lose weight suddenly can't lose weight herself? Karen found out the hard way at 42, gaining 15 pounds in six months, losing her period, battling depression, and watching her skin age before her eyes. Despite eating clean, exercising, and doing everything "right," her body had other plans.This is the episode you'll want to send to every woman in your life who's been told her labs look "fine."What You'll LearnWhy you can gain weight in perimenopause without changing your diet or exercise routineThe biological aging study that found perimenopausal women are aging faster on the inside and what stops itWhy estrogen is the metabolic master hormone and what happens to your hunger signals, blood sugar, cholesterol, and muscle when it dropsWhy being asymptomatic in perimenopause does not mean nothing is happening to your heart, brain, and bonesWhy it is never too late to start hormone replacement therapyWhy insulin and insulin-like growth factor may be driving estrogen receptor positive breast cancer more than anyone is talking aboutWhy women with a history of breast cancer are not automatically disqualified from hormone replacement therapy and why most doctors have it wrongHow GLP-1s are changing the game for menopausal womenThe truth about breast cancer, estrogen receptors, and why insulin may be a bigger driver than anyone is talking aboutEpisode Timeline:01:07 Meet Karen Martel04:10 Karen's Personal Perimenopause Wake-Up Call09:09 Why You Cannot Out-Diet or Out-Exercise Hormone Loss17:21 What Estrogen Actually Does in the Body25:12 HRT Delivery Methods and Why Form Matters26:28 Breast Cancer, Estrogen Receptors, and the Insulin Connection33:48 The Vaginal Estrogen Contradiction37:08 Estrogen as the Most Powerful Anti-Aging Tool38:56 The Pharmaceutical Incentive Behind the Anti-Hormone Narrative44:35 Menopausal Weight Gain and Where GLP-1s Fit In53:13 Is It Ever Too Late to Start Hormone Replacement59:39 Women Deserve Better Standards of Care1:02:06 The Statistics That Should End the Debate1:05:38 Topical Estrogen and Why Ingredients MatterFind Karen MartelWebsite: karenmartel.comTo talk to a member of Dr. Jenn's team and learn more about working with Dr. Jenn visit: https://calendly.com/stephanie-1031/clarity-callTo get your copy of Dr. Jenn's book, The Smart Woman's Guide to Breast Cancer, visit: https://tinyurl.com/SmartWomansBreastCancerGuideConnect with Dr. Jenn:Website:  https://www.perfeqtionimaging.com/Facebook: https://www.facebook.com/DrJennSimmonsInstagram: https://www.instagram.com/drjennsimmons/YouTube: https://www.youtube.com/@dr.jennsimmons

Episode metadata supplied by the publisher feed · Published Apr 24, 2026

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In this episode of Keeping Abreast, Dr. Jenn Simmons sits down with hormone specialist Karen Martel to talk about what's really driving the metabolic chaos of perimenopause and menopause and why the solution most women need is the one they've been told to fear. They also tackle one of the most misunderstood topics in women's health: the relationship between estrogen, metabolic health, and breast cancer. What happens when a nutrition expert who helps women lose weight suddenly can't lose weigh...

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141: The Hormone They Told You to Fear Is the One That Could Change Your Life with Karen Martel

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