146 Clonidine

Episode 146 – Clonidine   Welcome to the first in a little duo of episodes on oral alpha 2 agonists. This week, I'll be talking about clonidine, and next week, I'm going to talk about guanfacine – another oral alpha 2 agonist – and compare and contrast the 2 for you in terms of use and indications. Clonidine is a really useful psychopharmacological agent that is quite commonly used as both an event medication as well as a daily adjunct to baseline medications.   So, I thought we'd do a bit of a deep dive into clonidine and the things you, as professionals, need to know about this medication.   Here's what you'll learn: ·         Indications for and uses of clonidine as both an event- and a daily adjunctive medication in Veterinary Behaviour Medicine. ·         Why clonidine might be a good choice for hyper-aroused, hyper-active and hyper-vigilant patients. ·         When clonidine might be a better choice than guanfacine. ·         Potential drug interactions and contraindications.   Here are the 2 published papers I mention in the episode: Ogata, N. and Dodman, N.H., 2011. The use of clonidine in the treatment of fear-based behavior problems in dogs: an open trial. Journal of Veterinary Behavior, 6(2), pp.130-137.   Pflaum, K., Albright, J., Cox, S. and Smith, J., 2026. Pharmacokinetics of Orally Administered Clonidine in Dogs. Journal of Veterinary Pharmacology and Therapeutics.   This is a bit of a whistlestop tour into clonidine, but if you'd like to dive even deeper, I've got you covered – My PSYCHOACTIVE course contains everything you need to know: https://katrin-jahn.mykajabi.com/psychoactive   And here is the Professional Guides E-Book I mention in the episode, which includes a handout about clonidine: https://katrin-jahn.mykajabi.com/trinity-ebook   If you liked this episode of the show, Veterinary Behaviour Chat, please LEAVE A 5-STAR REVIEW, like, share, and subscribe!   Facebook Group: Join The Veterinary Behaviour Community on Facebook   You can CONNECT with me: Website: Visit my website Trinity Veterinary Behaviour Instagram: Follow Trinity Veterinary Behaviour on Instagram Trinity Veterinary Behaviour Facebook: Join us on Trinity Veterinary Behaviour's Facebook page Trinity Veterinary Behaviour YouTube: Subscribe to Trinity Veterinary Behaviour on YouTube LinkedIn Profile: Connect with me on LinkedIn   Thank you for tuning in!