EPISODE · Aug 21, 2026 · 18 MIN
1467-抗生素诱导的细菌膜囊泡介导蛋白质水平转移
from 聊聊Sci
这项研究揭示了细菌在抗生素压力下通过膜囊泡进行蛋白质水平转移的新机制。研究人员开发了一套Cre-loxP遗传系统，成功证实了这种转移不仅发生在大肠杆菌内部，还存在于不同菌种之间。实验发现，抗生素诱导细菌群体分化为两种状态：一种是激活膜应激反应并分泌囊泡的供体细胞，另一种是抑制该反应并摄取蛋白质的受体细胞。这种蛋白质的传递能显著增强受体细菌的抗生素持久性，帮助它们在致命药物浓度下存活。该发现为理解细菌耐药性提供了新视角，并可能催生针对持久性细胞的新型治疗策略。References:Wen A X, Bos J, Panda D, et al. Antibiotics stimulate protein transfer to persister cells[J]. Science, 2026, 392(6805): eadx3972.前往小宇宙评论区与主播互动
Embed this episode
Ready to play
1467-抗生素诱导的细菌膜囊泡介导蛋白质水平转移
0:00
18:59
1×
No transcript for this episode yet
Similar Episodes
No similar episodes found.
Similar Podcasts
Forfeiture Book Review: Ecocide and Sci-Fi
JP et al.
A whizz bang review of the complex themes in the new ecological Sci-Fi novel, FORFEITURE by JP Nebra
Deep Dream State
Neural Nets And Pretty Patterns
Deep Dream State is a full-cast dystopian sci-fi and desire horror audio drama by Neural Nets and Pretty Patterns. As the originating work of desire horror, it locates the uncanny inside wanting itself. While conventional horror positions you against a threat, desire horror implicates you in it. The horror emerges from recognition: the realization of why characters stay, and why surrender feels like relief. Since 2017, the show has used research in dream science, surveillance studies, behavioral economics, and advertising technology to examine systems of control through immersive sound design and full-cast performance.
Frequently Asked Questions
How long is this episode of 聊聊Sci?
This episode is 18 minutes long.
When was this 聊聊Sci episode published?
This episode was published on August 21, 2026.
Can I download this 聊聊Sci episode?
Yes. Use the download control on the episode player to save the publisher-provided media file.
URL copied to clipboard!