EPISODE · Aug 25, 2026 · 25 MIN
1489-大脑螺旋：小鼠皮层旋转波的结构与协调
from 聊聊Sci
这项研究利用大规模脑成像与电生理技术，揭示了小鼠大脑中普遍存在的一种名为“旋转波（rotating waves）”的神经活动模式。这些电信号波在大脑皮层上呈圆形轨迹传播，且主要以体感皮层为中心，其形成机制与该区域特有的环形轴突排列结构密切相关。研究发现，这种旋转活动在左右半球及感官与运动区域之间呈镜像对称，并与丘脑、纹状体等深层脑结构的神经元放电高度同步。通过行为实验，研究者证实旋转波受觉醒状态调节，可由触觉刺激诱发，并与视觉-运动任务中的正确表现显著相关。这表明旋转波是跨越多个脑区的分布式组织原则，通过轴突连接的几何布局引导神经信号的流动，从而协调感知与行动。References:Ye Z, Ladd A E, MacKenzie N, et al. Brain-wide topographic coordination of rotating waves[J]. Science, 2026, 392(6804): eadx1369.前往小宇宙评论区与主播互动
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1489-大脑螺旋：小鼠皮层旋转波的结构与协调
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