1540-裸盖菇素与大脑状态的场景对齐研究 episode artwork

EPISODE · Sep 4, 2026 · 27 MIN

1540-裸盖菇素与大脑状态的场景对齐研究

from 聊聊Sci

这项研究通过对62名成年人进行大规模神经影像实验,揭示了赛洛西宾(psilocybin)如何重塑大脑功能。研究利用功能磁共振成像(fMRI)和脑电图(EEG)技术,发现在药物作用下,大脑在静息、冥想、听音乐和观看电影等不同情境中展现出高度结构化且与环境一致的活动模式。这种被称为“情境对齐”(context alignment)的神经重组,打破了以往认为致幻剂仅导致脑部无序或熵增的观点。数据表明,个体感受到的自我溶解和边界感消失越强烈,其大脑活动与当前环境的对齐程度就越高,这种状态被称为“嵌入感”(embeddedness)。此外,这种神经模式的转变与参与者在服药次日所表现出的心态积极变化密切相关。最终,该研究通过机器学习分析证明,致幻剂引发的大脑重组并非杂乱无章,而是将神经生物学变化与深刻的主观体验及行为转变联系在了一起。References:Stoliker D, Novelli L, Khajehnejad M, et al. Psychedelics align brain activity with context[J]. Nature, 2026: 1-12.前往小宇宙评论区与主播互动

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1540-裸盖菇素与大脑状态的场景对齐研究

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