#180 Beta-Blockers & REDUCE-AMI Trial: Beyond Journal Club Segment with NEJM Group episode artwork

EPISODE · Jun 25, 2025 · 26 MIN

#180 Beta-Blockers & REDUCE-AMI Trial: Beyond Journal Club Segment with NEJM Group

from Core IM | Internal Medicine Podcast · host Core IM Team

How much do beta blockers help after a heart attack, even when the heart’s pumping well? In this episode, we revisit the origins of beta blockers in post-MI care, examine how evidence evolved, and explore the REDUCE-AMI trial, which questions whether beta blockers are still needed for all.Listen to this latest episode of Beyond Journal Club, a collaboration between Core IM and NEJM Group, where we put research into context tracing the arc of evidence, dissecting the clinical question, and exploring what the findings could mean for real-world patient care🔹 Sponsor: NEJM Fellowship Program, click here to learn more and/or apply!🔹 Transcript and Show NotesTimestamps:(00:48) | Background on Beta Blockers and Their Mechanism(02:41) | Historical Context of Beta Blockers in Heart Disease(04:56) | Capricorn Trial and Its Impact(07:17) | Emergence of Doubts About Beta Blockers(10:09) | Introduction to the REDUCED-AMI Trial(15:52) | Discussion on Trial Interpretation and Clinical Implications(16:18) | Comparison with Other Trials and Future DirectionsTags:  CoreIM, Internal Medicine, Primary Care, Medical Education, IMCore, Physician Assistant, Nurse Practitioner, Medical Student, Cardiology Find the best disability insurance for you: https://www.patternlife.com/disability-insurance?campid=497840Our Sponsors:* Check out Branch Basics and use my code branchbasics.com/COREIM for a great deal: https://branchbasics.com* Check out FIGS and use my code FIGSRX for a great deal: https://wearfigs.com* Check out Quince for high-quality clothes with affordable pricing and use code quince.com/coreim Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

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#180 Beta-Blockers & REDUCE-AMI Trial: Beyond Journal Club Segment with NEJM Group

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How long is this episode of Core IM | Internal Medicine Podcast?

This episode is 26 minutes long.

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This episode was published on June 25, 2025.

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How much do beta blockers help after a heart attack, even when the heart’s pumping well? In this episode, we revisit the origins of beta blockers in post-MI care, examine how evidence evolved, and explore the REDUCE-AMI trial, which questions...

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