#195 Antibiotic Duration & BALANCE Trial: Beyond Journal Club with NEJM Group episode artwork

EPISODE · Dec 10, 2025 · 21 MIN

#195 Antibiotic Duration & BALANCE Trial: Beyond Journal Club with NEJM Group

from Core IM | Internal Medicine Podcast · host Core IM Team

Antibiotic duration for bacteremia is something most of us learned by habit, not by trial data. In this episode, we walk through the BALANCE trial and use it as a lens to revisit how 1) host, 2) organism, and 3) source should guide treatment. When shorter really is enough, and when it isn’t?🔹 Sponsor: Oakstone CMEUse the code "CORE30" for 30% off: https://www.coreimpodcast.com/MKSAP 🔹 Transcript and ShownotesTimestamp(02:58) | Host, Organism, Source: The Core Framework Behind Duration(09:02) | How Evidence Shifted Practice(11:27) | The BALANCE Trial: Short-Course vs Standard-Course Therapy(18:55) | Where does this leave us?Tags: CoreIM, Internal Medicine, Infectious disease, Evidence-Based Medicine, Clinical Reasoning, Hospital Medicine, Medical EducationFind the best disability insurance for you: https://www.patternlife.com/disability-insurance?campid=497840Our Sponsors:* Check out ElevenReader and use my code PODCAST for a great deal: https://elevenreader.io* Check out FIGS and use my code FIGSRX for a great deal: https://wearfigs.comAdvertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

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#195 Antibiotic Duration & BALANCE Trial: Beyond Journal Club with NEJM Group

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