20 Questions That Will Change How You Think About GLP-1s episode artwork

EPISODE · Jul 29, 2026 · 46 MIN

20 Questions That Will Change How You Think About GLP-1s

from Weight Loss And ... · host Holly Wyatt & James Hill

GLP-1 medications are the single most requested topic on the show, no contest. But with so much noise on social media, in doctors' offices, and everywhere in between, sorting fact from fiction has never been trickier. Some of what's out there is spot-on. Some of it is dangerously wrong.So this week, Holly and Jim are flipping the format. Instead of another lecture, they're putting GLP-1 knowledge to the test with a 20-question quiz covering everything from the basic biology of these medications to the questions doctors themselves don't always get right. Grab a pen, keep score, and see how you stack up.By the end of this episode, you'll have a clearer, science-backed answer to the questions you've been too afraid to ask or too confused by conflicting headlines to trust.Discussed on the episode:The surprising truth about what GLP-1 medications are actually doing to your body (hint: it's not what most people think)Whether feeling less hungry is really a sign the medication is "working"Why a stalled scale might be the most normal thing that could happen to youThe dosing myth that even well-meaning doctors sometimes get wrongWhat "success" really looks like when two people lose very different amounts of weightThe truth behind "Ozempic face" and hair loss and whether the meds are really to blameWhy almost everyone on a GLP-1 could benefit from one specific type of healthcare providerWhat to actually do (and not do) if you're eating less than 800 calories a day and still feel fineThe real answer to "can I ever come off the medication?"Why those "natural GLP-1" gummies and supplements deserve a healthy dose of skepticism

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