EPISODE · Jun 20, 2025 · 6 MIN
2025 biology talkshow : 救命藥物的生物工廠-基因轉殖生物製藥 (選修生物I)
from 雷比特生物空中講 · host 雷比特老師
探討基因轉殖技術在生物製藥領域的應用，解釋如何透過將特定基因導入生物體，使其成為生產藥物的「生物工廠」。首先區分兩種主要的生產平台：微生物（如大腸桿菌和酵母菌）因其高效、低成本的優勢，適合生產結構相對簡單的蛋白質，例如胰島素。相對地，哺乳動物細胞（如CHO細胞）則因能提供複雜的後轉譯修飾，成為生產如單株抗體等高階藥物的首選。此外，也提到昆蟲細胞、基因轉殖動物和植物等其他潛在的生產平台，並強調選擇何種「生物工廠」需綜合考量藥物複雜性、成本效益、產品品質及法規等因素。 Powered by Firstory Hosting
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2025 biology talkshow : 救命藥物的生物工廠-基因轉殖生物製藥 (選修生物I)
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