2025 biology talkshow: 顫抖的雙手-帕金森氏症 episode artwork

EPISODE · Dec 11, 2025 · 16 MIN

2025 biology talkshow: 顫抖的雙手-帕金森氏症

from 雷比特生物空中講 · host 雷比特老師

介紹帕金森氏症(Parkinson's Disease, PD)從發現至今的百年歷程與最新的治療突破。文章首先回溯了該病在 1817 年由詹姆斯·帕金森首次描述,並解了該病在生理層面的核心機制,即黑質中多巴胺神經元的死亡。闡述路易氏體 (Lewy Bodies) 是由錯誤摺疊的 alpha突觸核蛋白堆積而成,是導致神經元死亡的主要原因。同時,也探討腸腦軸線假說,指出該病可能始於腸道,而非大腦本身。最後,著重於現代治療的進展,包括經典的 左多巴 (L-DOPA) 療法、深腦刺激術 (DBS),以及 2024-2025 年的生物標記革命(如 alpha Syn-SAA)與具備疾病修飾潛力的老藥新用(如 GLP-1 激動劑)等新興曙光。 聽完後可以自主進行線上測驗,檢視學習成效喔~(需要登入gemini) 測驗網址  https://gemini.google.com/share/8eebbeb5ddbe Powered by Firstory Hosting

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2025 biology talkshow: 顫抖的雙手-帕金森氏症

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