212: When the Innovator Becomes the Patient: Manufacturing Reality vs. Patient Urgency with Jesús Zurdo - Part 2 episode artwork

EPISODE · Dec 4, 2025 · 22 MIN

212: When the Innovator Becomes the Patient: Manufacturing Reality vs. Patient Urgency with Jesús Zurdo - Part 2

from Smart Biotech Scientist | The CMC and Biomanufacturing Podcast for Bioprocess Development and Manufacturing Leaders · host David Brühlmann - CMC Development Leader, Biotech C-level Advisor, Business Strategist

What happens when cell therapy innovation meets real patient urgency? In this conversation, the barriers between scientist and patient all but vanish, bringing clarity—and a new sense of mission—to some of the biggest problems facing advanced therapy manufacturing and delivery.Meet Jesús Zurdo, a biotech leader whose three decades of experience in innovation took on a whole new perspective when he became a leukemia patient himself. Seamlessly straddling the worlds of industry and patient care, Jesús Zurdo brings a refreshingly honest, systems-level view to cell therapies, manufacturing bottlenecks, and the realities of getting therapies from the lab to bedside.Topics discussed:Experiences and lessons from stem cell registries and point-of-care manufacturing models (03:15)Challenges and potential of autologous and allogeneic cell therapies, including scalability and accessibility (06:08)The promise and limitations of in vivo cell therapy, delivery risks and patient safety (07:06)Reflections on current trends in manufacturing automation, delivery platforms, and the risk of overengineering (09:49)Barriers to wider adoption of advanced cell therapies, including hospital infrastructure and economic constraints (13:31)The case for earlier lines of treatment with new modalities and value in learning from actual patient experiences (14:30)The importance of integrating voices of patients, clinicians, and developers when solving complex problems (17:31)Why urgency and remembering our future roles as patients should guide therapy development (18:51)Ready for bioprocessing to serve patients, yours included? For more insights and hands-on support, please subscribe so you never miss the next perspective-shifting episode.Connect with Jesús Zurdo:LinkedIn: https://www.linkedin.com/in/jesuszurdoEmail: [email protected] step:Need fast CMC guidance? New on-demand CMC advisory → Learn more hereSupport the show

What happens when cell therapy innovation meets real patient urgency? In this conversation, the barriers between scientist and patient all but vanish, bringing clarity—and a new sense of mission—to some of the biggest problems facing advanced therapy manufacturing and delivery. Meet Jesús Zurdo, a biotech leader whose three decades of experience in innovation took on a whole new perspective when he became a leukemia patient himself. Seamlessly straddling the worlds of industry and patient car...

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212: When the Innovator Becomes the Patient: Manufacturing Reality vs. Patient Urgency with Jesús Zurdo - Part 2

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This episode was published on December 4, 2025.

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What happens when cell therapy innovation meets real patient urgency? In this conversation, the barriers between scientist and patient all but vanish, bringing clarity—and a new sense of mission—to some of the biggest problems facing advanced...

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