#22- Tired but Wired After 40 Why Stress Hits Differently in Midlife (and What Actually Helps) episode artwork

EPISODE · Dec 17, 2025 · 31 MIN

#22- Tired but Wired After 40 Why Stress Hits Differently in Midlife (and What Actually Helps)

from The Modern Midlife Collective · host Dr. Ade Akindipe, DNP, MBA, APRN, FNP-C and Dr. Jillian Woodruff, MD, FACOG, NCMP

Feeling exhausted but unable to shut your brain off at night? Waking up tired, crashing in the afternoon, and feeling constantly on edge—even though you’re taking care of yourself?In this episode, Dr. Jill and Dr. Ade explain why stress feels different in midlife and why strategies that used to work often stop working after 40. They break down how cortisol is supposed to function, how hormonal shifts change the stress response, and why many women feel dismissed when labs come back “normal.”This is a clear, physiology-based conversation about what’s actually happening in the midlife stress system—and how to support it without blaming yourself or chasing quick fixes.📩 Have a question or comment? Email us at [email protected]—we’d love to feature your thoughts in a future episode! Follow us on Instagram for updates and behind-the-scenes content.#TiredButWired #MidlifeStress #Perimenopause #WomenOver40 #ModernMidlifeCollective #MidlifeHealth #StressInMidlife #Cortisol #HormoneHealth #Perimenopause #MenopauseSupport #WomensHealth #NervousSystemHealth #ModernMidlifeCollective

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#22- Tired but Wired After 40 Why Stress Hits Differently in Midlife (and What Actually Helps)

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