#253 COVID-19 Vaccines with Dr Monica Gandhi

Answer all your burning questions (and your patients’ burning questions) about the different COVID-19 vaccines currently authorized in the US. Infectious diseases / HIV expert, Dr Monica Gandhi @MonicaGandhi9 (UCSF) joins us to cover: the Pfizer-BioNTech and Moderna novel mRNA vaccine mechanisms, trial data, and practicalities of who should receive them.  We discuss data around the Oxford-AstraZeneca adenovirus vaccine, which is authorized in the UK and India, and may be available in the US later this year.  Feel confident recommending COVID-19 vaccines to your patients! Episodes | Subscribe | Spotify | Swag! | Top Picks | Mailing List | [email protected] | Free CME! Credits Written and Produced by: Molly Heublein, MD Cover Art: Chris Chiu, MD, FACP, FAAP Infographic: Tima Karginov Hosts: Chris Chiu, MD, FACP, FAAP; Molly Heublein, MD; Paul Williams, MD, FACP Editor: Emi Okamoto MD (written materials); Clair Morgan of Nodderly.com (audio) Guest: Monica Gandhi, MD, MPH Sponsor: Panacea Financial This episode is supported by Panacea Financial, digital banking built for doctors, by doctors. At Panacea Financial you can have your own free personal banker and a support team that works around the clock- just like you do. Open your free checking account today at panaceafinancial.com Panacea Financial, a Division of Sonabank, Member FDIC Sponsor: VCU Health CEThe Curbsiders are partnering with VCU Health Continuing Education to offer FREE continuing education credits for physicians and other healthcare professionals. Visit curbsiders.vcuhealth.org. Time Stamps Intro, disclaimer, guest bio - 00:00  Guest one-liner, book recommendation - 3:40 Authorized vaccines in the US - 8:30 AstraZeneca vaccine mechanism- 9:26 mRNA vaccine mechanism - 10:30 Vaccine distribution issues (cold chain) - 16:05 mRNA safety - 18:24 mRNA vaccine efficacy/data from phase 3 trials - 19:40 How did we get this so quickly - 23:40 Vaccine impact on asymptomatic infection - 26:18 AstraZeneca trials - 28:20 Pregnancy - 35:10 Anaphylaxis - 37:10 Prior COVID-19 infection - 39:07 Side effects - 42:05 Pediatric patients - 45:12 Phases of role outs in the US -46:50 Herd immunity - 48:16 Thoughts of how to make this happen - 52:45 Preexisting conditions - 53:40 How long will immunity last - 57:15 Mutant strains - 58:25 Future of mRNA vaccines - 1:00:30 Take home points and Outro - 1:02:12