EPISODE · Jan 9, 2026 · 55 MIN
255 - Testosterone in 2026: What You Need to Know Now with Shalin Shah, "The Metabolic CEO" and Testosterone Expert
from The Amy Edwards Show · host Amy Edwards
Shalin Shah is the CEO of Marius Pharmaceuticals and widely known as The Metabolic CEO. He’s a leading voice in metabolic health and hormone therapy innovation, and one of the strongest advocates working to destigmatize testosterone for both men and women.In this episode, we go deep into what’s really happening with testosterone today — why levels are declining across the population, why this is not just a “male” issue, and why testosterone is foundational to metabolic health, longevity, mental health, bone density, and quality of life. Shalin breaks down complex science in a way that’s practical and empowering, and explains why testosterone deficiency is being massively underdiagnosed and undertreated.We talk about environmental toxins, sleep disruption, stress, lifestyle, and the long-term consequences of ignoring low testosterone — including cardiovascular disease, diabetes, depression, frailty, and increased all-cause mortality. We also explore the future of hormone therapy, why testing should be standard, and how innovation like oral testosterone could change access and outcomes for millions of people.This conversation is informative, eye-opening, and honestly a bit of a wake-up call — especially for anyone in midlife who wants to age strong, think clearly, and feel energized again.What we cover:Why testosterone levels are declining in men and womenTestosterone as a metabolic health marker, not a lifestyle drugThe role of sleep, stress, toxins, and modern lifeWhy fatigue, brain fog, depression, and low motivation are often hormonalThe truth about testosterone myths and stigmaWhy testing matters — and why baselines should start earlyThe difference between “normal” and “optimal” hormone levelsOral vs topical vs injectable testosteroneWhy muscle, bone health, and longevity are directly tied to hormonesWhat’s changing at the FDA — and why this moment mattersPanel: https://www.fda.gov/patients/fda-expert-panels/fda-expert-panel-testosterone-replacement-therapy-men-12102025?Comments: https://www.regulations.gov/document/FDA-2025-N-6743-0001/commentwww.kyzatrex.comhttps://www.instagram.com/themetabolicceo/Please remember to rate, review, and follow the show – and share with a friend!Check out our new Comedy Wellness Podcast: Anything But Mid, cohosted with Whitney Stropp:https://podcasts.apple.com/us/podcast/anything-but-mid/id1849386215https://www.youtube.com/@AnythingButMidFind Amy’s affiliates and discount codes: https://amyedwards.info/affiliatepageSky Rock Sedona: https://www.skyrocksedona.com/20% Discount Link:https://www.marriott.com/event-reservations/reservation-link.mi?id=1759866624184&key=CORP&app=resvlinkAll links: amyedwards.infoInstagram: @realamyedwardsFight For Her: fightforher.netTikTok: @themagicbabeYouTube: YouTube ChannelPodcast: The Amy Edwards Show PodcastFree Course: The Ageless MindsetFull Course: The Youthfulness HackWork with Amy: Book a Call Let’s get you to your HAPPIEST and most RADIANT! Book a call to apply to work together one-on-one: https://amyedwards.as.me/15mincallAmy’s hair by https://www.thecollectiveatx.comPodcast editing by https://podcastmagician.com/Get my FREE course "The Ageless Mindset: The Ultimate Guide to Look Younger and Feel Happier!" HERE: https://best-you-life.teachable.com/p/the-ageless-mindset-the-ultimate-guide-to-look-younger-feel-happierGet the full course “The Youthfulness Hack: The Secret System to Reverse Aging Fast and Create a New, Radiant You!” Out now! https://best-you-life.teachable.com/p/the-youthfulness-hack
What this episode covers
Shalin Shah is the CEO of Marius Pharmaceuticals and widely known as The Metabolic CEO. He’s a leading voice in metabolic health and hormone therapy innovation, and one of the strongest advocates working to destigmatize testosterone for both men and women.In this episode, we go deep into what’s really happening with testosterone today — why levels are declining across the population, why this is not just a “male” issue, and why testosterone is foundational to metabolic health, longevity, mental health, bone density, and quality of life. Shalin breaks down complex science in a way that’s practical and empowering, and explains why testosterone deficiency is being massively underdiagnosed and undertreated.We talk about environmental toxins, sleep disruption, stress, lifestyle, and the long-term consequences of ignoring low testosterone — including cardiovascular disease, diabetes, depression, frailty, and increased all-cause mortality. We also explore the future of hormone therapy, why testing should be standard, and how innovation like oral testosterone could change access and outcomes for millions of people.This conversation is informative, eye-opening, and honestly a bit of a wake-up call — especially for anyone in midlife who wants to age strong, think clearly, and feel energized again.What we cover:Why testosterone levels are declining in men and womenTestosterone as a metabolic health marker, not a lifestyle drugThe role of sleep, stress, toxins, and modern lifeWhy fatigue, brain fog, depression, and low motivation are often hormonalThe truth about testosterone myths and stigmaWhy testing matters — and why baselines should start earlyThe difference between “normal” and “optimal” hormone levelsOral vs topical vs injectable testosteroneWhy muscle, bone health, and longevity are directly tied to hormonesWhat’s changing at the FDA — and why this moment mattersPanel: https://www.fda.gov/patients/fda-expert-panels/fda-expert-panel-testosterone-replacement-therapy-men-12102025?Comments: https://www.regulations.gov/document/FDA-2025-N-6743-0001/commentwww.kyzatrex.comhttps://www.instagram.com/themetabolicceo/Please remember to rate, review, and follow the show – and share with a friend!Check out our new Comedy Wellness Podcast: Anything But Mid, cohosted with Whitney Stropp:https://podcasts.apple.com/us/podcast/anything-but-mid/id1849386215https://www.youtube.com/@AnythingButMidFind Amy’s affiliates and discount codes: https://amyedwards.info/affiliatepageSky Rock Sedona: https://www.skyrocksedona.com/20% Discount Link:https://www.marriott.com/event-reservations/reservation-link.mi?id=1759866624184&key=CORP&app=resvlinkAll links: amyedwards.infoInstagram: @realamyedwardsFight For Her: fightforher.netTikTok: @themagicbabeYouTube: YouTube ChannelPodcast: The Amy Edwards Show PodcastFree Course: The Ageless MindsetFull Course: The Youthfulness HackWork with Amy: Book a Call Let’s get you to your HAPPIEST and most RADIANT! Book a call to apply to work together one-on-one: https://amyedwards.as.me/15mincallAmy’s hair by https://www.thecollectiveatx.comPodcast editing by https://podcastmagician.com/Get my FREE course "The Ageless Mindset: The Ultimate Guide to Look Younger and Feel Happier!" HERE: https://best-you-life.teachable.com/p/the-ageless-mindset-the-ultimate-guide-to-look-younger-feel-happierGet the full course “The Youthfulness Hack: The Secret System to Reverse Aging Fast and Create a New, Radiant You!” Out now! https://best-you-life.teachable.com/p/the-youthfulness-hack
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255 - Testosterone in 2026: What You Need to Know Now with Shalin Shah, "The Metabolic CEO" and Testosterone Expert
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