#263 Ayahuasca, Trauma Healing & Plant Medicine Science | Jeff McNairy @Rythmia

Imagine throwing away your antidepressants and never needing them again. For about 85% of the people who sit with Dr. Jeff McNairy, that is exactly what happens. He is the Chief Medical Officer of Rythmia, the world's only medically licensed ayahuasca retreat, and he looks at the most stigmatized corner of mental health through a clinical lens: the chemistry, the screening, the data, and the integration work that decides whether change lasts. Meet our guest Dr. Jeff McNairy holds a doctorate in psychology and a master's in public health from UCLA. He ran locked psychiatric units in Pasadena and was administrative director of Passages Malibu before trying plant medicine himself in 2014. For 25+ years he has worked at the intersection of Western psychology and indigenous medicine, and today he runs the medical operation and Costa Rican licensing for Rythmia. Thank you to our partners Outliyr Biohacker’s Peak Performance Shop: get exclusive discounts on cutting-edge health, wellness, & performance gear Ultimate Health Optimization Deals: a database of of all the current best biohacking deals on technology, supplements, systems and more Latest Summits, Conferences, Masterclasses, and Health Optimization Events: join me at the top events around the world FREE Outliyr Nootropics Mini-Course: gain mental clarity, energy, motivation, and focus Key takeaways Ayahuasca pairs DMT with an MAOI vine so the compound survives digestion and reaches the brain It activates a gene that links the amygdala to the prefrontal cortex, letting stored trauma surface and release About 85% of guests who came off antidepressants to attend never go back on them Rythmia turns away ~22 people a day for SSRIs, benzodiazepines, heart conditions, bipolar 1, schizophrenia, or type 1 diabetes The ceremony is the start, not the finish: every guest gets a free 13-week integration program A "psychosomatic" purge (vomiting, yawning, sweating) is how the body lets go of held emotion Intention plus meditation may drive a real epigenetic effect, per emerging UK research The biggest red flag in plant medicine is a retreat without firm staff-guest boundaries Episode highlights 00:00 Intro 02:25 What ayahuasca actually is (DMT + MAOI) 05:22 What a week at Rythmia looks like 10:22 How emotions get stored in the body 12:31 85% come off antidepressants and don't go back 17:19 The free 13-week aftercare program 38:41 Foods that pull you out of the medicine 48:51 Testing biological age before and after 51:31 How Rythmia measures success (98%) 53:42 Breaking the hippie stereotype 57:59 When NOT to do ayahuasca 1:05:57 What he's building next   Links Watch it on YouTube: https://youtu.be/N6SdiFFKFTY  Full episode show notes: https://outliyr.com/263  Connect with Nick on social media Instagram Twitter (X) YouTube LinkedIn Easy ways to support Subscribe Leave an Apple Podcast review Suggest a guest Do you have questions, thoughts, or feedback for us? Let me know in the show notes above and one of us will get back to you! Be an Outliyr, Nick