269// Is the MTHFR gene mutation really keeping you from healing? with Jaclyn Downs episode artwork

EPISODE · Jun 19, 2025 · 51 MIN

269// Is the MTHFR gene mutation really keeping you from healing? with Jaclyn Downs

from THE BETTER BELLY PODCAST - Natural Constipation Remedies, Acid Reflux, Hormones, Gut Health, Functional Medicine

Do you have the MTHFR gene mutation, and feel like it may be what's holding you back from healing?Or - do you not know if you have the MTHFR gene SNP, but wonder if you have it, how much it might be impacting you healing, and what the best testing is for it? If you have ANY question as to how much the MTHFR gene may be impacting your healing, then you DON'T want to miss today's episode. On today's episode, I'm interviewing Functional Genomics expert, Jaclyn Downs, on all things MTHFR and gene mutations. I met Jaclyn recently in the Instagram comments section of my profile when she offered up some free help to someone asking a question about genes. I love Jaclyn's response so much, and upon doing some quick stalking, fell even more in love with her knowledge and approach to genes. Naturally - I just had to have her on the podcast to share her with you all.  A bit about Jaclyn: Jaclyn has a master's degree in Holistic Nutrition, a functional nutrigenomics certification from the NutriGenetic Research Institution, and is the author of the academically published book Enhancing Fertility Through Functional Medicine: Using Nutrigenomics to Solve ‘Unexplained’ Infertility. On top of gaining her functional nutrigenomics certification from the NutriGenetic Research Institution, Jaclyn helped to create the very same program by working a researcher for Bob Miller, a top genetics researcher, to help create his practitioner certification program. Whether you are new to the conversation on how genes impact our health, or you've been in it a while, I hope my conversation today with Jaclyn is going to help you feel empowered and hopeful that no matter what genes you have - you CAN heal your body.  TIMESTAMPS:00:00 - Introduction to MTHFR Gene Mutation 00:52 - Meet Jacqueline Downs: Functional Genomics Expert 01:38 - Podcast Introduction and Host Background 02:42 - Diving into MTHFR Gene Mutation 04:15 - Understanding Gene Expression vs. Gene Mutation 16:27 - The Role of Cofactors in Gene Function 20:46 - Practical Advice on Vitamin B Dosing 26:37 - Navigating Supplement Dosages and Deficiencies 27:42 - Genetic Testing vs. Functional Lab Testing 28:59 - Cost-Effective Testing Strategies 30:53 - Comprehensive Testing Bundles 32:05 - The Importance of Bile in Detoxification 33:02 - Choosing the Right Genetic Test 33:52 - The Role of Clinically Validated SNPs 38:02 - Personalized Genetic Concierge Services 40:21 - Evaluating Popular Genetic Experts 45:24 - How to Connect and Work with JacquelineEPISODES MENTIONED:214// Is this Gene Mutation Making Your ADHD Worse?216// ADHD and COMT Gene Mutation: Why You Need to Know CONNECT WITH THE GUEST:Follow on Instagram: @functionalgenomicsJaclyn's WebsiteGet Jaclyn's Free PDF: The "Big 3" Most Important GenesHave a 23andme report already and want Jaclyn to interpret it? Click here!Want Jaclyn to order her favorite genetic testing for you and interpret it? Click here! HEAL YOUR GUT:Option #1) 👉 Join the Better Belly Blueprint today!Want to learn how BBB works? Watch this FREE training walking you through how to heal, once and for all!Option #2) 👉 Work long-term, 1:1 with me as a Better Belly VIP client (Pay-in-full and payment plan options available)Want to make sure that VIP is right for you? Book a FREE 20 Min Application Call! RESOURCES:Get Full Access to my Liver Detox Protocol for only $7!Download my Free Constipation Relief GuideDownload the entire Better Belly Podcast Vault!Get the Functional Blood Chemistry Analysis Spreadsheet LINKS:JOIN → Join our FREE Facebook Group FOLLOW → @betterbellytherapies ASK → Ask a Question for the PodcastWORK WITH US → betterbellytherapies.com SHOW US YOUR LOVE:If this podcast episode positively impacted you, please leave a Rating and Review for the podcast. It'd mean so much! ❤️ *This episode was first published at BetterBellyTherapies.com/269 Mentioned in this episode:🚨 50% OFF BBB until Aug. 31 @ 11:59 PM EST 🚨 Have you been trying to fix your bloating, constipation, acid reflux, or PMS — and nothing has worked? If so, this is for you! Better Belly Blueprint is 50% OFF!! and you'll also get $588 in fast-track bonuses, free: ✅ 3 months of live group coaching with me ✅ Upload your labs → get your personalized healing plan in minutes ✅ 100+ recipes built around your exact food sensitivities ✅ A pocket coach you can text anytime, so you always know your next step 👉 Go to betterbellytherapies.com/blueprint to get 50% off healing NOW + $588 in fast-track bonuses. Ends Aug. 31 @ 11:59 PM EST!

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269// Is the MTHFR gene mutation really keeping you from healing? with Jaclyn Downs

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