270. 口腔感染与阿尔茨海默病之关联 episode artwork

EPISODE · Sep 9, 2025 · 17 MIN

270. 口腔感染与阿尔茨海默病之关联

from 知为谁 · host 知为谁

ScienceAlert 网站上的一篇文章探讨了阿尔茨海默病可能源于感染的惊人假设,而不仅仅是衰老大脑的疾病。文章着重介绍了2019年一项研究的发现,该研究将牙周病与阿尔茨海默病联系起来,指出导致慢性牙周病的病原体——牙龈卟啉单胞菌——存在于阿尔茨海默病患者的大脑中。该研究通过小鼠实验进一步证明,这种口腔感染可能导致淀粉样蛋白-β的产生增加,淀粉样蛋白-β是与阿尔茨海默病相关的蛋白质。研究人员甚至在未被诊断出阿尔茨海默病但存在相关病理的个体大脑中发现了细菌分泌的毒性酶,这表明感染可能是疾病的早期事件,而非晚期表现。尽管需要进一步研究,但这些发现为阿尔茨海默病的病因提供了一个强有力的调查方向。内容来源:https://www.sciencealert.com/the-cause-of-alzheimers-could-be-coming-from-within-your-mouth

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270. 口腔感染与阿尔茨海默病之关联

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