272 Slowing Biological Aging Naturally: Autophagy, Diet and Longevity with Leslie Kenny

What if one of the most powerful anti-aging tools already exists within your body? This episode explores autophagy, the body's natural cellular renewal system, and how activating it can support healthy aging and longevity. Longevity expert Leslie Kenny shares her personal journey of reversing autoimmune disease and translating cutting-edge science into practical strategies. Listeners will discover how autophagy promoting spermidine, proper nutrition, and baseline lifestyle habits influence cellular repair, resilience, and biological aging.  Leslie Kenny is the founder of Oxford Healthspan, a company focused on translating longevity science into practical health solutions. She is a longevity researcher with expertise in cellular aging, autophagy, and immune system modulation. Her career includes work in finance and policy before a personal medical crisis led her to transition into health science. She specializes in spermidine research and its role in activating autophagy and influencing the hallmarks of aging. She is co-founder of the Oxford Longevity Project, a nonprofit dedicated to education in healthy aging.  Episode Timeline  00:00 – Welcome and introduction  02:00 – Reframing aging as a modifiable biological process  03:50 – Leslie Kenny's autoimmune diagnosis and turning point  10:50 – Limitations of modern healthcare and the need for prevention  14:50 – What autophagy is and why it matters for longevity  17:00 – Spermidine and its role in cellular renewal pathways  21:30 – Nutrition, mushrooms, and dietary sources of spermidine  24:30 – Hallmarks of aging and systemic cellular decline  31:00 – Development of Primadine and supplement formulation science  37:00 – Practical strategies: fasting, diet, and supplementation  41:30 – Key takeaways on influencing biological agin  Connect with Leslie Kenny  https://oxfordhealthspan.com  Instagram: @lesliesnewprime @oxfordhealthspan @oxfordlongevityproject To try Primadine Spermidine Supplement:Code: GOLY15 Link: https://www.oxfordhealthspan.com/GOLY15 Please note that Dr. Lockitch retired from medical practice and does not diagnose, prescribe for or treat any medical conditions. Before ordering any product discussed in these podcasts, consult your health care practitioner. Connect with Dr. Gillian Lockitch  at https://www.askdrgill.com/ or email: [email protected]  Subscribe to Growing Older Living Younger on your favorite podcast platform and leave a review to help others discover the show.   Join the Growing Older Living Younger Community at https://www.facebook.com/groups/growingolderlivingyoungercommunity  Download Guide to Nature's Colorful Antioxidants 2026