#275 Why "Normal" Bloodwork Misses Years of Aging Cellular Drift & Multi-Omics Testing | Dr. Adrijana Kekic @futurome

Your annual physical came back "normal," so why do you still feel foggy, tired, and stuck? Dr. Adrijana Kekic says your biology has probably been drifting for years before any standard test notices. Former Mayo Clinic pharmacogenomics specialist and Futurome founder Dr. Adrijana Kekic reveals what a standard 30 to 100 marker panel misses, how multi-omics testing catches metabolic drift early, and why women age differently after 40. After a preventable pulmonary embolism nearly killed her, she rebuilt her own health and now maps cellular aging for people who look fine on paper. Meet our guest Dr. Adrijana Kekic is a pharmacist and nutritionist trained in genetics, one of the first pharmacogenomics clinical specialists at Mayo Clinic and winner of its 2023 Innovation Award. She founded Futurome, a precision health intelligence company that reads thousands of biomarkers to map cellular aging, with a special focus on female biology. Thank you to our partners Outliyr Biohacker’s Peak Performance Shop: get exclusive discounts on cutting-edge health, wellness, & performance gear Ultimate Health Optimization Deals: a database of of all the current best biohacking deals on technology, supplements, systems and more Latest Summits, Conferences, Masterclasses, and Health Optimization Events: join me at the top events around the world FREE Outliyr Nootropics Mini-Course: gain mental clarity, energy, motivation, and focus Key takeaways Standard panels lean on late markers; fasting insulin and HOMA-IR flag metabolic trouble years earlier. Multi-omics testing reads thousands of markers across genomics, proteomics, metabolomics, and microbiome. Cellular aging spikes around 40 and 60, the windows where personalization pays off most. The highest mitochondrial density in women sits in the ovaries; decline can surface there before any blood test. Perimenopause is estrogen swinging up and down, not just falling; it hides on standard labs. Women make about 50% less gut serotonin than men, so fasting protocols should differ by sex. Foundation first: sleep, magnesium, vitamin D, movement, and a CGM before advanced interventions. Episode highlights 0:00 Normal labs, hidden aging 6:09 What standard bloodwork misses 18:24 The two aging cliffs at 40 & 60 25:33 The perimenopause you don't notice 30:27 The ICU wake-up call 40:40 Foundation before shiny objects 46:18 Why men & women differ Links Watch it on YouTube: https://youtu.be/1P-vuKmzvtw  Full episode show notes: https://outliyr.com/275 Connect with Nick on social media Instagram Twitter (X) YouTube LinkedIn Easy ways to support Subscribe Leave an Apple Podcast review Suggest a guest Do you have questions, thoughts, or feedback for us? Let me know in the show notes above and one of us will get back to you! Be an Outliyr, Nick