#28: Hidradenitis Suppurativa

In this episode of Inflammatory Content, Dr. Kellen Cavagnero explores the debilitating skin disease hidradenitis suppurativa (HS) and takes a deep dive into a recent Immunity paper that comprehensively examines the role of tertiary lymphoid structures in HS pathogenesis. HS has long defied simple classification, with prevailing disease models emphasizing hair follicle dysfunction, aberrant wound healing, or chronic inflammation. This work adds a new dimension by implicating autoimmunity as a central contributor to HS pathogenesis, further underscoring the complexity of the disease.Relevant Links:• Paper: https://pmc.ncbi.nlm.nih.gov/articles/PMC12404358/• Commentary: https://pmc.ncbi.nlm.nih.gov/articles/PMC11790253/If you enjoy Inflammatory Content and want to help me keep the conversations going, consider supporting the podcast! You can write a review, share this episode with friends and colleagues, or make a donation to help keep the show ad-free and thriving. Your contributions, big or small, go directly toward covering production costs and allow me to bring you even more Inflammatory Content. You can donate directly here: https://venmo.com/Kellen-Cavagnero.I’d love to hear from you! Feel free to reach out with questions, feedback, or topic suggestions via email at [email protected], on X @KellenCavagnero, or connect with me on LinkedIn.Stay curious and keep exploring at www.inflammatorycontent.com