PODCAST · science
Inflammatory Content
by Kellen Cavagnero, Ph.D.
Inflammatory Content is a podcast about immunology and biomedical sciences more broadly. UC San Diego immunologist Dr. Kellen Cavagnero PhD reviews the latest high-impact original articles and discusses all things science with leading researchers in the field. Inflammatory Content has been featured in Nature and received sponsorship from the NIH.
Episodes
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#28: Hidradenitis Suppurativa
In this episode of Inflammatory Content, Dr. Kellen Cavagnero explores the debilitating skin disease hidradenitis suppurativa (HS) and takes a deep dive into a recent Immunity paper that comprehensively examines the role of tertiary lymphoid structures in HS pathogenesis. HS has long defied…
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#27: A Surprising New Role for Neutrophils in Wound Healing
In this episode of Inflammatory Content, Dr. Kellen Cavagnero breaks down a new Nature paper showing that a subset of skin neutrophils doesn’t just fight bacteria—they also build extracellular matrix (ECM). After injury, these neutrophils rapidly assemble rings of ECM around the wound that...
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#26: Spatial Proteomics Uncovers a Lifesaving Treatment for Severe Skin Drug Reactions
In this episode of Inflammatory Content, Dr. Kellen Cavagnero dives into a landmark 2024 Nature study by Thierry Nordman and colleagues, titled “Spatial proteomics identifies JAKi as treatment for a lethal skin disease.” This cutting-edge research changes the game for patients suffering from…
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#25: Immuno-endocrinology with Dr. Dequina Nicholas, Ph.D.
In this episode, Dr. Kellen Cavagnero is joined by Dr. Dequina Nicholas. Dr. Nicholas is an Assistant Professor at the University of California Irvine in the Department of Molecular Biology and Biochemistry. Her laboratory studies endocrine diseases, including type 2 diabetes and polycystic ovary...
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#24: AI Generated Podcast on Immune-Acting Fibroblasts
Today we’re going to do a journal club, but it will not be your run of the mill journal club. Everyone who knows me knows I am always searching for the latest technology that can increase my efficiency. Lately, I have been especially attuned to the newest developments in artificial...
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#23: The PhD Fellowship Application Survival Guide
One of the most common questions I get from undergraduate and graduate students is: How do I get a Ph.D. fellowship? During my Ph.D., I was fortunate to be awarded two fellowships, and I’ve received two more as a postdoc. In this solo episode, I provide an overview of the who, what, where, when,...
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#22: Mpox (formerly monkeypox) with Dr. Aaron Oom, Ph.D.
In this episode, Kellen is joined by Dr. Aaron Oom, a Postdoctoral Scholar in the lab of Dr. Mark Mulligan at NYU Langone Health. Aaron is an expert in virology and immunology. He completed his Ph.D. in the lab of Dr. John Guatelli’s at UC San Diego. Aaron has made significant contributions to…
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#21: Functional genomics identifies a novel therapeutic target for inflammatory bowel disease
Genome-wide association studies (GWAS) have identified thousands of disease-associated genetic variants. Many of these variants lie in non-coding regions of the genome, making interpretation of GWAS difficult and leading to poor translation into therapeutics. In this episode, Kellen reviews an...
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#20: Cancer, Metabolism, T cells, and Spatial Transcriptomics with Dr. Miguel Reina-Campos, Ph.D.
Dr. Miguel Reina-Campos is an Assistant Professor at the La Jolla Institute for Immunology in La Jolla, California. The Reina lab seeks to understand the underlying principles governing tissue immune networks that enable robust and long-term protection against infection and tumors. In this...
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#19: Lymphatics, stem cells, and postdocs with Dr. Shiri Gur-Cohen, Ph.D.
Dr. Gur-Cohen is an Assistant Professor of Medicine in the Division of Regenerative Medicine at the University of California, San Diego. Dr. Gur-Cohen’s work has unearthed the lymphatic capillary network as a novel stem cell niche component, and her multidisciplinary strategy has advanced our...
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#18: Unconventional T cells with Dr. Mitchell Kronenberg, Ph.D.
In this episode, Kellen speaks with Dr. Mitchell Kronenberg. Mitch is the chief scientific officer of the La Jolla Institute for Immunology, an adjunct professor at UC San Diego, and the co-director of a collaborative effort between the La Jolla Institute and UC San Diego called the Program in...
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#17: Gut microbiome therapeutics with Dr. Amir Zarrinpar, M.D. Ph.D.
In this episode, Kellen speaks with Dr. Amir Zarrinpar. Amir is a board-certified gastroenterologist and an assistant professor at UC San Diego in the department of medicine. He completed his undergrad at Harvard, M.D. and Ph.D. at UCSD, and postdoc at the Salk Institute in Satchin Panda’s lab.…
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#16: Inflammatory bowel disease and proteomics with Dr. David Gonzalez, Ph.D.
In this episode, Kellen speaks with Dr. David Gonzalez. David is an associate professor at UC San Diego in the pharmacology department of the school of medicine and the Skaggs school of pharmacy. He’s also the founder and director of the UCSD collaborative center for multiplexed proteomics. The...
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#15: Antimicrobial resistance with Dr. Victor Nizet, M.D.
In this episode, Kellen interviews Dr. Victor Nizet, a distinguished professor of pediatrics and pharmaceutical sciences at UCSD and the vice chair of basic research in the department of pediatrics at UCSD. Kellen and Victor discuss one of the Nizet lab’s recent publications (led by Josh Sun,...
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#14: Fibrosis in CNS autoimmunity with Dr. Richard Daneman, Ph.D.
In this episode, Kellen sits down for a conversation with Richard Daneman, an associate professor of neurosciences and pharmacology at UCSD. Kellen and Rich discuss the Daneman lab’s recent paper identifying a novel role of fibroblasts in the central nervous system as well as Rich’s philosophies...
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#13: Immune fibroblastic cells with Dr. Richard Gallo, M.D. Ph.D.
In this episode, Kellen is joined by his thesis advisor Dr. Richard Gallo, a Distinguished Professor and the Founding Chairman of the Department of Dermatology at the University of California, San Diego. Kellen and Rich discuss two recent publications from the Gallo lab related to the host…
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#12: Omental fat, the “policeman of the abdomen”
Omental adipose tissue has been considered an important component of host defense since at least 1906 when it was deemed “the policeman of the abdomen”. The precise mechanisms underlying omental host defense, however, remain elusive. Here, Kellen discusses a recent publication investigating how...
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#11: Microbiome therapeutics with Dr. Alan O’Neill, Ph.D.
This is a special episode of Inflammatory Content as it is our first episode with a guest! Dr. Alan O’Neill, Ph.D. joins Kellen to discuss his work on microbiome therapeutics—highlighting his recent report in eLife (link below)—as well as his overall scientific journey. Dr. O’Neill’s recent...
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#10: Cuts, commensals, and chemokines
Getting physically injured is no fun—it can often take long periods of time to recover. What if we could accelerate the wound healing process? Here, Kellen dissects an original article, titled “The commensal skin microbiota triggers type I IFN-dependent innate repair responses in injured skin”,...
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#9: ILC2s and cancer
Cutting-edge approaches to combat tumor development involve transplantation of anti-tumor T cells and natural killer cells. Natural killer (NK) cells belong to a greater family of innate lymphoid cells which includes the more recently described group 1, 2, and 3 innate lymphoid cells (ILCs).…
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#8: Epigenome editing
Fragile X syndrome is a genetic disorder and the leading cause of intellectual disability and autism. There is no treatment. In this episode, Kellen discusses recent gene therapy advances for treating Fragile X syndrome. The article highlighted in this episode was written by X. Shawn Liu and...
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#7: COVID19 PSA and unconventional T cells
Medical systems around the world need our help with COVID19. After sharing an important PSA, Kellen dives into the topic of unconventional T cells. These novel immune subsets have unique functions with great therapeutic potential. In this episode, a seminal paper by Michael Crowther and…
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#6: Biofilm architecture
Antibiotic resistance is an enormous public health problem. The prevalence of superbugs is increasing over time, whereas the number of drugs available to treat these microbes is not. Bacterial communities called biofilms harbor strains of bacteria that persist in the face of antibiotic therapy....
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#5: Bacteria and immunotherapy
Engineering bacteria to kill cancer cells… Sounds like science fiction, right? Well, it’s actually all science, no fiction! Sreyan Chowdhury and colleagues from Tal Danino’s lab at Columbia University describe this novel therapeutic approach in their recent Nature Medicine publication,...
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#4: ILC2s and neutrophils
In this episode, Kellen covers a topic near and dear to his heart – group two innate lymphoid cells, or ILC2s. Specifically, Kellen discusses the original article titled “Neutrophils restrain allergic airway inflammation by limiting ILC2 function and monocyte–dendritic cell antigen presentation”,...
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#3: Commensal viruses
When most people think of viruses, they usually think of the negative aspect of viruses –- agents of infectious disease. We, however, are not most people! Not only are viruses useful biotechnological tools, but they are also capable of promoting health outcomes in disease models. In this episode,...
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#2: Plant medicine
Plants are a great source of fiber and micronutrients, which makes them an important component of a heathy diet. However, it was recently shown that there is another aspect of plants that allows them to contribute to well-being –- exosomes. In this episode, Kellen reviews a paper published in…
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#1: Introduction
Brief introduction of what this podcast will entail and the reason behind its creation. To help us spread science, please consider writing a review, sharing this episode with your friends and colleagues, or donating to support our work (Venmo @Kellen-Cavagnero). Please reach out to us via email...
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ABOUT THIS SHOW
Inflammatory Content is a podcast about immunology and biomedical sciences more broadly. UC San Diego immunologist Dr. Kellen Cavagnero PhD reviews the latest high-impact original articles and discusses all things science with leading researchers in the field. Inflammatory Content has been featured in Nature and received sponsorship from the NIH.
HOSTED BY
Kellen Cavagnero, Ph.D.
CATEGORIES
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Frequently Asked Questions
How many episodes does Inflammatory Content have?
Inflammatory Content currently has 28 episodes available on PodParley. New episodes are automatically indexed when they're published to the podcast feed.
What is Inflammatory Content about?
Inflammatory Content is a podcast about immunology and biomedical sciences more broadly. UC San Diego immunologist Dr. Kellen Cavagnero PhD reviews the latest high-impact original articles and discusses all things science with leading researchers in the field. Inflammatory Content has been featured...
How often does Inflammatory Content release new episodes?
Inflammatory Content has 28 episodes. Check the episode list to see recent publication dates and frequency.
Where can I listen to Inflammatory Content?
You can listen to Inflammatory Content on PodParley by clicking any episode. We provide an embedded audio player for direct listening, and you can also subscribe via your preferred podcast app using the RSS feed.
Who hosts Inflammatory Content?
Inflammatory Content is created and hosted by Kellen Cavagnero, Ph.D..
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