28. Why Your Probiotic Probably Isn't Working, And What to Take Instead episode artwork

EPISODE · Jun 21, 2026 · 1H 15M

28. Why Your Probiotic Probably Isn't Working, And What to Take Instead

from Functional Medicine Reality Podcast · host Dr. Mark Su MD, Functional Medicine Practitioner for Health and Longevity

Ready to stop guessing and finally get a clear plan?Join Dr. Su for the Ask Dr. Mark Clinical Q&A Call, a small-group call limited to about five people each month where you can bring your real questions and get real direction.Book your spot: https://go.rootseekhealth.com/askdrmarkIf you've ever taken a probiotic for weeks, felt nothing, and quietly concluded they just don't work for you, this episode is for you.You are not wrong that something isn't working. You may just have never been told that the probiotic on the shelf and the probiotic in the research paper are often not the same thing at all.Why this episode mattersThe microbiome is one of the fastest-moving areas in all of health research, and most patients are either taking nothing, taking the wrong thing, or being sold on claims that have no clinical backing. Dr. Mark Su sits down with Ben Myers, an educator and representative for Microbiome Labs, for a conversation that cuts through the noise. Ben brings years of deep education in probiotic science, strain-specific research, and the expanding connections between gut health, mental health, and women's health.This is not a product pitch. It is a conversation between two people who want you to understand what is actually happening in your gut, and why that matters for the rest of your body.What you will learnThe difference between dead-strain, live-culture, and spore-based probiotics, and why the category you are taking changes everything about your results.Why strain specificity is the single most important and most overlooked factor in probiotic selection, and how the same species name on two different bottles can mean completely different outcomes.The science behind psychobiotics, including how one specific strain has been shown in peer-reviewed human clinical trials to regulate cortisol, shift tryptophan metabolism toward serotonin and melatonin, and change brainwave patterns in people under stress.How the vaginal microbiome works, why recurring bacterial vaginosis and yeast infections keep coming back after antibiotics, and what precision probiotic therapy is starting to offer as an alternative.Why fixing the gut first is still the foundation, and how that foundational work connects to skin health, sinus health, mental health, and far more than most people expect.A moment worth notingOne of the most honest exchanges in this conversation happens early. Dr. Su acknowledges how hard it is for patients to know who to trust in the supplement space, especially when practitioners themselves sometimes have financial incentives tied to what they recommend. It is a rare moment of transparency, and it sets the tone for everything that follows.Dr. Su's perspectiveThe goal was never to overwhelm you with strain names and research codes. The goal is to give you enough of the picture that you can stop throwing things at the wall and start asking better questions. The research on the gut is not slowing down. And while we do not have every answer yet, we have more than enough to take meaningful, targeted action.Links and resourcesMicrobiome Labs: microbiomelabs.comAbout Ben MyersBen Myers is an educator and representative for Microbiome Labs with years of experience working alongside functional medicine practitioners. He came to this work through his own health journey and a deep passion for making complex science accessible. This was his first podcast appearance. It will not be his last.Ready to stop guessing and finally get a clear plan?Join Dr. Su for the Ask Dr. Mark Clinical Q&A Call, a small-group call limited to about five people each month where you can bring your real questions and get real direction.Book your spot: https://go.rootseekhealth.com/askdrmarkOr download the free Lab Results Guide if you have ever been told your labs are normal while still feeling terrible: https://labsoptin.rootseekhealth.com/labs/Connect with Dr. Surootseekhealth.com | @rootseekhealthDisclaimer: This podcast is for educational purposes only.  Information discussed is not intended for diagnosis, curing, or prevention of any disease and is not intended to replace advice given by a licensed healthcare practitioner. This podcast and its guests may have direct or indirect financial interests associated with products mentioned.

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Ready to stop guessing and finally get a clear plan? Join Dr. Su for the Ask Dr. Mark Clinical Q&A Call, a small-group call limited to about five people each month where you can bring your real questions and get real direction. Book your spot: https://go.rootseekhealth.com/askdrmark If you've ever taken a probiotic for weeks, felt nothing, and quietly concluded they just don't work for you, this episode is for you. You are not wrong that something isn't working. You may just have never ...

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28. Why Your Probiotic Probably Isn't Working, And What to Take Instead

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