288: Anti-depressant news, Ruined by dating a hot guy, Finding a dream job

In today's show, the Dr's discuss new evidence about anti-depressant treament and then discuss the following questions:  I think I have messed up my dopamine reward system and I don't know how to fix it or if I want to. I am early 40's, single and have been in many relationships. I don't have trouble attracting men. I think if I just decided it was time then I would settle for one but to me it is boring and mundane and I only feel excited by unpredictable, magnetic dynamics with men. For the last couple of years I've had an online FWB who lives overseas. He has a bit of a high profile and so the reward I felt from attracting him and engaging with him long term has been really high. Now that I attracted someone so unattainable I can't get excited about anyone else. I didn't used to be like this. I had plenty of loser bfs in the past. Wtf is wrong with me? And if I don't fix it, will I end up alone and be a miserable old person? My partner's parents are in their early 70s and still love what they do, jumping out of bed to start work each day as they did 40 years ago. Both work in creative fields.  It's not clear if they found the perfect careers, or if they would take the same excitable, have-at-it attitude to any path they had followed.  Are people who find their dream job genetically predisposed to do so? Is it in their own personalities to work with such passion and positivity or does everyone have that potential, if the right job comes along?