29: From Monoclonals to Gene Therapy: Tips for Biopharma Process Development w/ Neil Templeton - Part 1

In this enlightening episode, we're joined by Neil Templeton, Director in Upstream Process Development at Solid Biosciences, who pulls back the curtain on the intricate world of bioprocess development and manufacturing. Neil delves into the shifting paradigms of the industry, sharing his expert insights on overcoming the unique challenges that surface when transitioning from R&D to GMP production. This episode is packed full of invaluable knowledge that's crucial for anyone looking to succeed in this field. Key points we discuss include: Strategies and solutions for overcoming the obstacles faced when transitioning from R&D to GMP production. The importance and application of Design of Experiment (DOE) approaches, and their role in understanding critical process parameters. The role of metabolite analysis in optimizing processes and ensuring their robustness. Get connected with Neil Templeton: LinkedIn: https://www.linkedin.com/in/neil-templeton Next Step: Elevate your bioprocess development strategy — Grab your free assessment now: https://bruehlmann-consulting.com Free 5-day email course, The CMC Failure Chain: the five recurring CMC mistakes that put your promising program at risk → Get it here Support the show