3 17 2025

Hi, This Week in Medicine, we will be discussing

New England Journal of Medicine

Axillary Surgery in Breast Cancer — Primary Results of the INSEMA Trial

Antibiotic Treatment for 7 versus 14 Days in Patients with Bloodstream Infections

Liberal or Restrictive Transfusion Strategy in Aneurysmal Subarachnoid Hemorrhage

 Journal of  American Medical Association

Atezolizumab in High-Risk Locally Advanced Squamous Cell Carcinoma of the Head and Neck

A Randomized Clinical Trial

Adjuvant PD-1 Blockade With Camrelizumab for Nasopharyngeal Carcinoma

The DIPPER Randomized Clinical Trial

 British Medical Journal

Projections for prevalence of Parkinson’s disease and its driving factors in 195 countries and territories to 2050

 Lancet

Global, regional, and national prevalence of adult overweight and obesity, 1990–2021, with forecasts to 2050: a forecasting study for the Global Burden of Disease Study 2021

  journal of Hepatology

Frailty and risk of metabolic dysfunction-associated steatotic liver disease and other chronic liver diseases

Non-invasive assessment of severe liver fibrosis in patients with Fontan-associated liver disease: The VALDIG-EASL FONLIVER cohort

 Gastroenterology

Creeping Fat–Derived Free Fatty Acids Induce Hyperplasia of Intestinal Muscularis Propria Muscle Cells: A Novel Link Between Fat and Intestinal Stricture Formation in Crohn’s Disease

 Clinical Gastroenterology

Preinjection With Ligation-Assisted Endoscopic Mucosal Resection for Barrett’s Dysplasia and Early Esophageal Adenocarcinoma: Characteristic Histological Features of the Depth of Resection

 Rheumatology 

Changes in Long‐Term Glucocorticoid Use Among Older Adults After New Diagnosis of Late‐Onset Rheumatoid Arthritis

 Journal of Clinical Rheumatology 

Risk of Malignancy Related to Ixekizumab in Patients With Psoriatic Arthritis or Axial Spondyloarthropathy: Systematic Review and Meta-analysis

  Circulation

 Long-Term Efficacy and Safety of Acoramidis in ATTR-CM: Initial Report From the Open-Label Extension of the ATTRibute-CM Trial

 Journals of the American College of Cardiology

Predictors of Outcomes of Reintervention After Transcatheter Aortic Valve Replacement

 Journal of Clinical Endocrinology & Metabolism

Weight-Specific Grip Strength as a Novel Indicator Associated With Cardiometabolic Risk in Children: The EMSNGS Study

 Diabetes care

The Association Between Cost-Related Insulin Rationing and Health Care Utilization in U.S. Adults With Diabetes

 The American Journal of Respiratory and Critical Care Medicine

Impact of Fluid Balance on the Development of Lung Injury

  Clinical Journal of American Society of Nephrology

Perspectives and Experiences of Patients with AKI: A Systematic Review

 Kidney International reports

Randomized Trial of Pegmolesatide for the Treatment of Anemia in Patients With Nondialysis CKD

Influence of Individual- and Area-Level Social Determinants of Health on Likelihood of Living Versus Deceased Donor Kidney Transplantation